CANCER - BONE

CANCER - BONE:

• 2023
• The Synergistic, anti-cancer effect of CBD and DOX in Osteosarcoma.  https://link.springer.com/article/10.1007/s12094-023-03119-3 
• 2022
• Experience with Medical Marijuana for Cancer Patients in Palliative Setting.https://pubmed.ncbi.nlm.nih.gov/35915672/ 
• Pre-Clinical Study Suggests CBG Is More Effective Than CBGA on Stomach and Bone Cancers:  https://www.cannabisbusinesstimes.com/article/study-suggests-cbg-more-effective-than-cbga-on-stomach-bone-cancer/
• Study Explores How Different Marijuana Extracts Kill Types Of Cancer Cells:  https://www.marijuanamoment.net/study-explores-how-different-marijuana-extracts-kill-types-of-cancer-cells/
• The heterogeneity and complexity of Cannabis extracts as antitumor agents:  http://www.oncotarget.com/index.php?
• A randomized trial of medical cannabis (MC) in patients with advanced cancer (AC) to assess impact on opioid use and cancer-related symptoms:  https://ascopubs.org/doi/abs/10.1200/JCO.2019.37.31_suppl.109
• Best 4 Cannabinoids For Treating Cancer: https://www.youtube.com/watch?time_continue=1&v=SrN6vsN5ccc&feature=emb_logo
• 2019
• Paradoxical effects of JZL184, an inhibitor of monoacylglycerol lipase, on bone remodelling in healthy and cancer-bearing mice. (UK/ France/ Italy/ Cyprus/ Switzerland, full, 2019) https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(19)30356-1/fulltext
• The Endocannabinoid/Endovanilloid System in Bone: From Osteoporosis to Osteosarcoma. (Italy, full, 2019) https://www.mdpi.com/1422-0067/20/8/1919/htm 
• WIN55,212-2-Induced Expression of Mir-29b1 Favours the Suppression of Osteosarcoma Cell Migration in a SPARC-Independent Manner. (Italy, full, 2019) https://www.mdpi.com/1422-0067/20/20/5235/htm 
• Cannabinoid receptor 2-selective agonist JWH015 attenuates bone cancer pain through the amelioration of impaired autophagy flux induced by inflammatory mediators in the spinal cord. (China, link to PDF, 2019) https://www.spandidos-publications.com/10.3892/mmr.2019.10772 
• 2018
• Anti-Tumorigenic Properties of Omega-3 Endocannabinoid Epoxides. (USA, click “researchgate” for download, 2018) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Antitumorigenic+Properties+of+Omega-3+Endocannabinoid+Epoxides&btnG 
• Bortezomib And Endocannabinoid/Endovanilloid System: A Synergism In Osteosarcoma. (Italy, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S1043661818310387 
• 2017
• Anti-proliferative, pro-apoptotic and anti-invasive effect of EC/EV system in human osteosarcoma. (Italy, full, 2017) https://www.oncotarget.com/article/17089/
• Recent advances in understanding and managing cancer pain. (USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482325/ 
• A peripherally restricted cannabinoid 1 receptor agonist as a novel analgesic in cancer-induced bone pain. (USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095738/#__ffn_sectitle 
• Emerging therapeutic targets in cancer induced bone disease: A focus on the peripheral type 2 cannabinoid receptor. (UK, link to download, 2017) http://eprints.whiterose.ac.uk/113366/ 
• Morin Suppresses Astrocyte Activation and Regulates Cytokine Release in Bone Cancer Pain Rat Models. (China, abstract, 2017) https://pubmed.ncbi.nlm.nih.gov/28618070/ 
• Bufalin attenuates cancer-induced pain and bone destruction in a model of bone cancer. (China, abstract, 2017) https://link.springer.com/article/10.1007%2Fs00210-017-1419-7 
• 2016
• The role of mifamurtide in chemotherapy-induced osteoporosis of children with osteosarcoma. (Italy, link to PDF, 2016) https://www.researchgate.net/publication/311792373_The_Role_of_Mifamurtide_in_Chemotherapy-induced_Osteoporosis_of_Children_with_Osteosarcoma 
• A Single Intrathecal or Intraperitoneal Injection of CB2 Receptor Agonist Attenuates Bone Cancer Pain and Induces a Time-Dependent Modification of GRK2. (China, abstract, 2016) https://link.springer.com/article/10.1007%2Fs10571-016-0349-0 
• Inhibition of autophagy and enhancement of endoplasmic reticulum stress increase sensitivity of osteosarcoma Saos-2 cells to cannabinoid receptor agonist WIN55,212-2. (China, abstract, 2016) https://www.semanticscholar.org/paper/Inhibition-of-autophagy-and-enhancement-of-stress-Zhang-Bi/cb61b9c8b50355a776a461ca04b1cf3b8f4ad9a1 
• 2015
• Potentiation of the antitumor activity of adriamycin against osteosarcoma by cannabinoid WIN-55,212-2. (China, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580018/ 
• The secreted protein acidic and rich in cysteine is a critical mediator of cell death program induced by WIN/TRAIL combined treatment in osteosarcoma cells. (Italy/ Canada, full, 2015) https://www.spandidos-publications.com/ijo/48/3/1039 
• Intrathecal Injection of JWH-015 Attenuates Bone Cancer Pain Via Time-Dependent Modification of Pro-inflammatory Cytokines Expression and Astrocytes Activity in Spinal Cord. (China, abstract, 2015) https://link.springer.com/article/10.1007/s10753-015-0168-3    
• 2013
• New Study: Cannabis Can Inhibit The Pain Associated With Bone Cancer (news–2013) https://www.theweedblog.com/new-study-cannabis-can-inhibit-the-pain-associated-with-bone-cancer/