CANCER – MELANOMA

CANCER – MELANOMA: (results are mixed, using just CBD might be better in melanoma.)

• 2024
• Examining 1-year mortality risk among patients with malignant melanoma undergoing immune checkpoint inhibitor therapy with a history of cannabis use. https://ascopubs.org/doi/10.1200/JCO.2024.42.16_suppl.11046 
• Examining the risk of immune checkpoint inhibitor-related toxicity among patients with melanoma and their history of cannabis use. https://ascopubs.org/doi/10.1200/JCO.2024.42.16_suppl.e21539
• 2023
• In-Vitro Anti-proliferative effects of cannabis extract PHEC-66 on Melanoma cell lines. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605078/ 
• Neuronal Cannabinoid CB1 receptors suppress the growth of melanoma brain metastases by inhibiting glutamatergic signalling. https://www.mdpi.com/2072-6694/15/9/2439 
• Gene profiling of Cannabis sativa mediated apoptosis in human melanoma cells. https://ar.iiarjournals.org/content/43/3/1221 
• 2022
• Experience with Medical Marijuana for Cancer Patients in Palliative Setting.https://pubmed.ncbi.nlm.nih.gov/35915672/ 
• Study Explores How Different Marijuana Extracts Kill Types Of Cancer Cells:  https://www.marijuanamoment.net/study-explores-how-different-marijuana-extracts-kill-types-of-cancer-cells/
• The heterogeneity and complexity of Cannabis extracts as antitumor agents:  http://www.oncotarget.com/index.php?
• A randomized trial of medical cannabis (MC) in patients with advanced cancer (AC) to assess impact on opioid use and cancer-related symptoms:  https://ascopubs.org/doi/abs/10.1200/JCO.2019.37.31_suppl.109
• Best 4 Cannabinoids For Treating Cancer: https://www.youtube.com/watch?time_continue=1&v=SrN6vsN5ccc&feature=emb_logo
• 2019
• Cannabinoid Signaling in the Skin: Therapeutic Potential of the "C(ut)annabinoid" System. (Hungary, full, 2019) https://www.mdpi.com/1420-3049/24/5/918/htm
• Cannabidiol-from Plant to Human Body: A Promising Bioactive Molecule with MultiTarget Effects in Cancer. (Romania, full, 2019) https://pubmed.ncbi.nlm.nih.gov/31775230/ 
• Cannabinoids as a Potential New and Novel Treatment for Melanoma: A Pilot Study in a Murine Model. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/30691796/ 
• 2018
• The Therapeutic Potential of Cannabinoids in Dermatology. (USA, full, 2018) http://www.skintherapyletter.com/dermatology/cannabinoids-potential/ 
• The role of lipid signaling in the progression of malignant melanoma. (Hungary/ Germany, abstract, 2018) https://link.springer.com/article/10.1007/s10555-018-9729-x 
• Review of Common Alternative Herbal "Remedies" for Skin Cancer. (USA, abstract, 2018) https://www.semanticscholar.org/paper/Review-of-Common-Alternative-Herbal-%E2%80%9CRemedies%E2%80%9D-for-Li-Kampp/05c443601d26801066563b63eae4582abf514d24 
• Dermatology-Related Uses of Medical Cannabis Promoted by Dispensaries in Canada, Europe, and the United States. (Canada, abstract, 2018) https://journals.sagepub.com/doi/abs/10.1177/1203475418808761?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&journalCode=cmsa& 
• 2017
• Pharmaceuticals containing cannabinoids may be effective against skin diseases, say researchers (news–2017) http://www.news-medical.net/news/20170418/Pharmaceuticals-containing-cannabinoids-may-be-effective-against-skin-diseases-say-researchers.aspx
• Topical cannabinoids may help to treat skin diseases (news–2017) http://www.medicalnewstoday.com/articles/316968.php
• Should I prescribe marijuana for my patients? Senior users weigh in (news–2017) http://www.jweekly.com/2017/06/18/should-i-prescribe-marijuana-for-my-patients-senior-users-weigh-in/
• Standardized Cannabis sativa extract attenuates tau and stathmin gene expression in the melanoma cell line. (Iran, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673704/ 
• Cannabidiol upregulates melanogenesis through CB1 dependent pathway by activating p38 MAPK and p42/44 MAPK. (Republic of Korea, abstract, 2017) https://www.sciencedirect.com/science/article/abs/pii/S0009279716304343?via%3Dihub 
• Tumor-promoting effects of cannabinoid receptor type 1 in human melanoma cells. (Italy, abstract, 2017) https://www.sciencedirect.com/science/article/abs/pii/S0887233317300188  
• 2016
• Marijuana to fight skin cancer in major human trial (news–2016) http://blog.sfgate.com/smellthetruth/2016/07/06/marijuana-to-fight-skin-cancer-in-major-human-trial/
• Preclinical and Clinical Assessment of Cannabinoids as Anti-Cancer Agents. (USA/ Egypt, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054289/ 
• 2015
• Exploiting Cannabinoid-Induced Cytotoxic Autophagy to Drive Melanoma Cell Death. (UK/ Italy/ Spain, full, 2015) https://www.jidonline.org/article/S0022-202X(15)37287-0/fulltext 
• Differential role of cannabinoids in the pathogenesis of skin cancer. (Germany, link to download, 2015) https://www.alchimiaweb.com/blogfr/wp-content/uploads/2015/10/2014-LS-Differential-role-CB-skin-cancer-Glodde-N-Differential-role-of-cannabinoids-in-the-pathogenesis-of-skin-cancer-.pdf 
• AM251 induces apoptosis and G2/M cell cycle arrest in A375 human melanoma cells. (Italy, abstract, 2015) https://www.semanticscholar.org/paper/AM251-induces-apoptosis-and-G2%2FM-cell-cycle-arrest-Carpi-Fogli/1b03691f73edcd6ac8683e7e757ab66331c74700 
• Melanoma research in Hungary: promising results in a previously orphan tumor (Hungary, abstract in English, link to PDF of full in Hungarian, 2015) https://www.researchgate.net/publication/287009446_Melanoma_research_in_Hungary_Promising_results_in_a_previously_orphan_tumor