COLITIS

COLITIS: also see Bowel Disorders

• 2024
• Cannabis and Stomach Pain: https://realmofcaring.org/cannabis-and-stomach-pain/?utm_source=Klaviyo&utm_medium=campaign&utm_campaign=08%2F08%20Cannabis%20and%20Stomach%20Pain&_kx=pQ9r0zLSMIUHWYqd0TqbvxV_DAPx16hhlJ43MlrVzik.UvV543
• Therapeutics effects of Cannabinoids on Ulcerative Colitis: A systematic review and meta analysis of Randomized Controlled Trials. https://jhsmr.org/index.php/jhsmr/article/view/1041 
• 2023
• Dietary cannabidiol activates PKA/AMPK signaling and attenuates chronic inflammation and leaky gut in DSS-induced colitis mice. https://onlinelibrary.wiley.com/doi/full/10.1002/mnfr.202300446 
• Cannabis improves clinical outcomes and Quality of life in patients with chronic pouchitis. https://journals.lww.com/acgcr/fulltext/2023/08000/cannabis_improves_clinical_outcomes_and_quality_of.20.aspx 
• 2019
• Use of Medical Cannabis in Patients With Inflammatory Bowel Disease (interview–2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366240/
• Medical Marijuana For Ulcerative Colitis (news–2019) https://www.marijuanadoctors.com/conditions/ulcerative-colitis/
• In-hospital outcomes of inflammatory bowel disease in cannabis users: a nationwide propensity-matched analysis in the United States. (USA, full, 2019) http://atm.amegroups.com/article/view/25637/24217 
• Members of the endocannabinoid system are distinctly regulated in inflammatory bowel disease and colorectal cancer. (Austria/ Germany, full, 2019) https://www.nature.com/articles/s41598-019-38865-4 
• Insights into the role of cannabis in the management of inflammatory bowel disease. (Canada, full, 2019) https://journals.sagepub.com/doi/full/10.1177/1756284819870977 
• A Quantitative Analysis of Colonic Mucosal Oxylipins and Endocannabinoids in Treatment-Naïve and Deep Remission Ulcerative Colitis Patients and the Potential Link With Cytokine Gene Expression. (Norway/ Sweden, full, 2019) https://academic.oup.com/ibdjournal/article/25/3/490/5198657 
• Association between cannabis use and complications related to ulcerative colitis in hospitalized patients: A propensity matched retrospective cohort study. (USA, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708902/ 
• Use of Medical Cannabis in Patients With Inflammatory Bowel Disease. (USA, interview, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366240/ 
• The non-euphoric phytocannabinoid cannabidivarin counteracts intestinal inflammation in mice and cytokine expression in biopsies from UC pediatric patients. (Italy/ Canada/ Malta, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S1043661819311077?via%3Dihub 
• Effects of O-1602 and CBD on TNBS-induced colonic disturbances. (China, abstract, 2019) https://onlinelibrary.wiley.com/doi/abs/10.1111/nmo.13756 
• 2018
• Cannabis and cannabis oil for the treatment of ulcerative colitis. (news – 2018)
  https://www.cochrane.org/CD012954/IBD_cannabis-and-cannabis-oil-treatment-ulcerative-colitis
• Cannabis for the treatment of ulcerative colitis. (Canada, full in English & Spanish, 2018) https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD012954.pub2/full 
• The Use of Complementary and Alternative Medicine in Patients With Inflammatory Bowel Disease. (USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111500/ 
• Intestinal P-glycoprotein exports endocannabinoids to prevent inflammation and maintain homeostasis. (USA/ UK, full, 2018) https://www.jci.org/articles/view/96817 
• Can We Target Endogenous Anti-inflammatory Responses as a Therapeutic Strategy for Inflammatory Bowel Disease? (UK/ USA, full, 2018) https://academic.oup.com/ibdjournal/article/24/10/2123/5055343 
• Cannabis, cannabinoids and the endocannabinoid system – is there therapeutic potential for inflammatory bowel disease? (UK, full, 2018) https://academic.oup.com/ecco-jcc/article/13/4/525/5173479 
• The Role of Cannabis in the Management of Inflammatory Bowel Disease: A Review of Clinical, Scientific, and Regulatory Information: Commissioned by the Crohn’s and Colitis Foundation. (USA, full, 2018) https://academic.oup.com/ibdjournal/article/25/3/427/5144402 
• The Use of Cannabinoids in Colitis: A Systematic Review and Meta-Analysis. (UK, link to PDF, 2018) https://www.researchgate.net/publication/322738763_The_Use_of_Cannabinoids_in_Colitis_A_Systematic_Review_and_Meta-Analysis 
• 2017
• Active ingredients in both hot peppers and cannabis calm the gut’s immune system (news–2017) https://medicalxpress.com/news/2017-04-ingredients-hot-peppers-cannabis-calm.html
• Chili peppers, marijuana may reduce gut inflammation (news–2017) http://www.medicalnewstoday.com/articles/317128.php
• To Calm the Gut, Look to Weed and Hot Peppers (news–2017) https://www.inverse.com/article/30714-marijuana-weed-spicy-food-gut
• Cannabinoid Chewing Gum Enters Phase II Trial (news–2017) https://www.technologynetworks.com/tn/news/cannabinoid-chewing-gum-enters-phase-ii-trial-286694
• We are not alone: a case for the human microbiome in extra intestinal diseases. (India, full, 2017) https://gutpathogens.biomedcentral.com/articles/10.1186/s13099-017-0163-3 
• Cannabidiol restores intestinal barrier dysfunction and inhibits the apoptotic process induced by Clostridium difficile toxin A in Caco-2 cells. (Italy, full, 2017) https://journals.sagepub.com/doi/full/10.1177/2050640617698622 
• Host-probiotic interaction: new insight into the role of the endocannabinoid system by in vivo and ex vivo approaches. (Italy, full, 2017) https://www.nature.com/articles/s41598-017-01322-1 
• Cannabinoids for treating inflammatory bowel diseases: where are we and where do we go? (Germany/ Austria, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388177/ 
• Anti-Inflammatory Activity in Colon Models Is Derived from Δ9- Tetrahydrocannabinolic Acid That Interacts with Additional Compounds in Cannabis Extracts. (Israel, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627671/ 
• Elevation of arachidonoylethanolamide levels by activation of the endocannabinoid system protects against colitis and ameliorates remote organ lesions in mice. (China, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740744/ 
• G protein-coupled receptor 55 (GPR55) expresses differently in patients with Crohn's disease and ulcerative colitis. (Poland, abstract, 2017) https://www.tandfonline.com/doi/abs/10.1080/00365521.2017.1298834?journalCode=igas20& 
• 2016
• Cannabis as a Treatment for Inflammatory Bowel Disease (news–2016) https://www.marijuanatimes.org/cannabis-as-a-treatment-for-inflammatory-bowel-disease/
• Abnormal cannabidiol attenuates experimental colitis in mice, promotes wound healing and inhibits neutrophil recruitment. (Canada/ Poland/ Germany, full, 2016) https://journal-inflammation.biomedcentral.com/articles/10.1186/s12950-016-0129-0 
• Endocannabinoids in the Gut. (USA, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940133/ 
• The CB2 receptor and its role as a regulator of inflammation. (Canada, full, 2016) https://link.springer.com/article/10.1007/s00018-016-2300-4 
• Anti-inflammatory effect of cannabinoid agonist WIN55, 212 on mouse experimental colitis is related to inhibition of p38MAPK. (China, full, 2016) https://www.wjgnet.com/1007-9327/full/v22/i43/9515.htm 
• An Orally Active Cannabis Extract with High Content in Cannabidiol attenuates Chemically-induced Intestinal Inflammation and Hypermotility in the Mouse. (Italy, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047908/ 
• Activation of Cannabinoid Receptor 2 Ameliorates DSS-Induced Colitis through Inhibiting NLRP3 Inflammasome in Macrophages. (China/ USA, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017608/ 
• Therapeutic Use of Cannabis in Inflammatory Bowel Disease. (USA, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193087/ 
• Role of cannabinoids in gastrointestinal mucosal defense and inflammation. (Hungary, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333598/ 
• Fatty acid amide hydrolase (FAAH) blockade ameliorates experimental colitis by altering microRNA expression and suppressing inflammation. (USA, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154806/ 
• Cannabis in Inflammatory Bowel Diseases: from Anecdotal Use to Medicalization? (Israel, link to PDF, 2016) https://www.ima.org.il/FilesUploadPublic/IMAJ/0/228/114217.pdf 
• Dietary Supplement Therapies for Inflammatory Bowel Disease: Crohn's Disease and Ulcerative Colitis. (USA, link to PDF, 2016) https://www.researchgate.net/publication/283729505_Dietary_Supplement_Therapies_for_Inflammatory_Bowel_Disease_Crohn's_Disease_and_Ulcerative_Colitis 
• Cannabinoid Receptor 2 Functional Variant Contributes to the Risk for Pediatric Inflammatory Bowel Disease. (Italy, click “sativaistacated” for download, 2016) https://www.sativaisticated.com/wp-content/uploads/2017/06/Cannabinoid-Receptor-2-Functional-Variant-Contributes-to-the-Risk-for-Pediatric-Inflammatory-Bowel-Disease-Cannabis-Marijuana-Research-for-nflammatory-Bowel-Disease-IBD.pdf 
• Application of carbon nanotubes as the carriers of the cannabinoid, 2- arachidonoylglycerol: Towards a novel treatment strategy in colitis. (Iran, abstract, 2016) https://www.sciencedirect.com/science/article/abs/pii/S002432051630666X  
• 2015
• What ailments does medical marijuana help? (news–2015) http://www.mnn.com/health/fitness-well-being/stories/what-ailments-does-medical-marijuana-help
• Monoglyceride lipase deficiency causes desensitization of intestinal cannabinoid receptor type 1 and increased colonic μ-opioid receptor sensitivity. (Austria/ Germany, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556478/ 
• The GPR55 antagonist CID16020046 protects against intestinal inflammation. (Austria/ Germany, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587547/ 
• Conformational Restriction Leading to a Selective CB2 Cannabinoid Receptor Agonist Orally Active Against Colitis. (France/ Belgium, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329582/    
• 2014
• L. Acidophilus and the CB2 Receptor (news–2014) https://www.sclabs.com/l-acidophilus-and-the-cb2-receptor/