DEPRESSION

DEPRESSION:

• 2026
• New community resource for behavioral health:
  • https://www.apghealth.com/ Empowering Minds, Transforming Lives: At APG Health, we provide comprehensive mental health services designed to help you thrive. Whether you’re seeking innovative treatments, compassionate counseling, or expert medication management, we’re here to support your journey toward improved mental well-being. Explore our core services below.
• 2025
• Chronic cannabidiol administration modulates depressive and cognitive alterations induced by social isolation in male mice. https://www.sciencedirect.com/science/article/abs/pii/S0166432824005643
• 2024
• Novel Insight into the antidepressant effect of cannabidiol: possible involvement of the 5-HT1A, CB1, GPR55, and PPARy receptors. https://academic.oup.com/ijnp/advance-article/doi/10.1093/ijnp/pyae064/7918373?login=false
• Alterations in plasma endocannabinoid concentrations among individuals with major depression treated with electroconvulsive therapy. https://pubmed.ncbi.nlm.nih.gov/38796933/ 
• Cannabinoids in the treatment of selected mental illnesses: practical approach and overview of the literature. https://www.thieme-connect.de/products/ejournals/html/10.1055/a-2256-0098 
• Effectiveness of Medical Cannabis for the treatment of Depression: A naturalistic outpatient study. https://www.thieme-connect.com/products/ejournals/abstract/10.1055/a-2215-6114 
• 2023
• Cross-disorder GWAS meta analysis of endocannabinoid DNA variations in major depressive disorder, bipolar disorder, attention deficit hyperactivity disorder, autism spectrum disorder and schizophrenia. https://pubmed.ncbi.nlm.nih.gov/37924773/ 
• Physician-Guided medical cannabis treatment for co-morbid anxiety and depression disorders in a Canadian Multidisciplinary clinic: A retrospective review. https://www.endocannabinoidmedicine.com/academicarticle/physician-guided-medical-cannabis-treatment-for-comorbid-anxiety-and-depression-disorders-in-a-canadian-multidisciplinary-clinic-a-retrospective-review/ 
• Psilocybin shows promising and sustained antidepressant effects in patients with Major Depressive Disorder. https://www.endocannabinoidmedicine.com/news/psilocybin-shows-promising-and-sustained-antidepressant-effects-in-patients-with-major-depressive-disorder/
• Psilocybin, an effective treatment for major depressive disorder in Adults - a systematic review. https://www.cpn.or.kr/journal/view.html?uid=1577&vmd=Full& 
• Possible Effects of the Endocannabinoid system on the Pathophysiology of depression: Medical Treatment approached based on this system. https://cms.turkmedstudj.com/Uploads/Article_60707/tmsj-10-86-En.pdf 
• Under the umbrella of depression and Alzheimer's disease pathophysiology: Can cannabinoids be a Dual pleiotropic therapy? https://www.sciencedirect.com/science/article/pii/S1568163723001575 
• Best marijuana strains for depression: https://cannigma.com/strain/best-marijuana-strains-for-depression/?utm_source=The%20Cannigma%20B2B&utm_medium=email&utm_campaign=Newsletter%2016.05.23%20%2801H0CN6Y1H4AMHXCT1KMYNCMFG%29&_kx=_uv58WsEi9s6bfI1NDeC26zVRyr2jgRfDXqxHEq9LD4%3D.J8JtEm
• Assessment of Clinical Outcomes of medicinal cannabis therapy for depression: analysis from the UK medical Cannabis Registry. https://pubmed.ncbi.nlm.nih.gov/36573268/
• Cannabidiol in the Treatment of Post-Traumatic Stress Disorder: A case series: (USA, Abstract, 2019) https://www.liebertpub.com/doi/full/10.1089/acm.2018.0437 
• The therapeutic role of Cannabidiol in mental health: a systematic review:  https://link.springer.com/article/10.1186/s42238-019-0012-y#Sec15
• Does cannabis use modify the effect of post-traumatic stress disorder on severe depression and suicidal ideation? Evidence from a population-based cross-sectional study of Canadians    https://journals.sagepub.com/doi/full/10.1177/0269881119882806
• Cannabis could help alleviate depression and suicidality among people with PTSD:  https://www.med.ubc.ca/news/cannabis-could-help-alleviate-depression-and-suicidality-among-people-with-ptsd/
• Cannabis shows potential for treating PTSD: New study: https://www.toronto.com/opinion-story/9681557-cannabis-shows-potential-for-treating-ptsd-new-study/
• 2020
• Medicinal cannabis for psychiatric disorders: a clinically-focused systematic review. (Australia/ UK, full, 2020) https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12888-019-2409-8 
• Experiencing sexual harassment by males and associated substance use & poor mental health outcomes among adolescent girls in the US. (USA, full, 2020) https://www.sciencedirect.com/science/article/pii/S2352827318302842?via%3Dihub 
• Dual pharmacological inhibitor of endocannabinoid degrading enzymes reduces depressive-like behavior in female rats. (USA/ India, full, 2020) https://www.sciencedirect.com/science/article/abs/pii/S0022395619307356?via%3Dihub 
• Cannabidiol prescription in clinical practice: an audit on the first 400 patients in New Zealand. (New Zealand, link to PDF, 2020) https://www.researchgate.net/publication/339046590_Cannabidiol_prescription_in_clinical_practice_an_audit_on_the_first_400_patients_in_New_Zealand 
• Antidepressant-like effects of β-caryophyllene on restraint plus stress-induced depression. (Republic of Korea, abstract, 2020) https://www.sciencedirect.com/science/article/pii/S0166432819313348?via%3Dihub 
• Depressive symptoms moderate cannabis use for young adults in a Text-Delivered randomized clinical trial for cannabis use disorder. (USA, abstract, 2020) https://www.sciencedirect.com/science/article/abs/pii/S0306460319313279?via%3Dihub 
• Relationship between cannabis use frequency and major depressive disorder in adolescents: Findings from the National Survey on Drug Use and Health 2012-2017. (USA, abstract, 2020) https://www.sciencedirect.com/science/article/abs/pii/S0376871620300326 
• Negative mood as a mediator of the association between insomnia severity and marijuana problems in college students. (USA, abstract, 2020) https://pubmed.ncbi.nlm.nih.gov/31997499/ 
• Antidepressant-like effects of pharmacological inhibition of FAAH activity in socially isolated female rats. (Italy, abstract, 2020) https://www.sciencedirect.com/science/article/abs/pii/S0924977X20300018 
• Dietary intake of polyunsaturated fatty acids alleviates cognition deficits and depression-like behaviour via cannabinoid system in sleep deprivation rats. (China, abstract, 2020) https://www.sciencedirect.com/science/article/pii/S0166432819317218 
• 2019
• New link between endocannabinoids and exercise may help in treatment of depression.
  (news/ abst – 2019) https://neurosciencenews.com/depression-exercise-endocannabinoids-14714/
• Medical marijuana can help your stress-induced depression. (news – 2019)
  https://www.thegrowthop.com/cannabis-health/medical-marijuana-can-help-your-stress-induced-depression
• Comorbid tobacco and other substance use and symptoms of anxiety and depression among hospitalised orthopaedic trauma patients. (Australia, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337866/ 
• Characterizing chronic pain in late adolescence and early adulthood: prescription opioids, marijuana use, obesity, and predictors for greater pain interference. (USA, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344139/ 
• From Substance Use Disorders in Life to Autopsy Findings: A Combined Case-Record and Medico-Legal Study. (Sweden, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427694/ 
• Benefit of Tetrahydrocannabinol versus Cannabidiol for Common Palliative Care Symptoms. (USA/ Canada, full, 2019) https://www.liebertpub.com/doi/full/10.1089/jpm.2018.0658?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed& 
• Depression as a Neuroendocrine Disorder: Emerging Neuropsychopharmacological Approaches beyond Monoamines. (Venezuela/ Colombia/ USA, full, 2019) https://www.hindawi.com/journals/aps/2019/7943481/ 
• Cannabis and Mood Disorders. (USA/ Canada, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329464/ 
• Diabesity and mood disorders: Multiple links through the microbiota-gut-brain axis. (Austria, full, 2019) https://www.sciencedirect.com/science/article/pii/S0098299718300748?via%3Dihub 
• Influence of the CB1 and CB2 cannabinoid receptor ligands on the activity of atypical antidepressant drugs in the behavioural tests in mice. (Poland, full, 2019) https://www.sciencedirect.com/science/article/pii/S0091305719304873?via%3Dihub 
• A National Survey of Marijuana Use Among US Adults With Medical Conditions, 2016- 2017. (USA, full, 2019) https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2751558 
• Management of chronic pain with Jalaprakshalana (water-wash) Shodhita (processed) Bhanga (Cannabis sativa L.) in cancer patients with deprived quality of life: An openlabel single arm clinical trial. (Jalaprakshalana = water curing until water is clear.- GSC) (India, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891996/ 
• Marijuana use and major depressive disorder are additively associated with reduced verbal learning and altered cortical thickness. (USA, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933749/ 
• Serum Endocannabinoid and Mood Changes after Exercise in Major Depressive Disorder. (USA, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727944/ 
• Cannabidiol (CBD) for Treatment of Neurofibromatosis-related Pain and Concomitant Mood Disorder: A Case Report. (Canada, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944157/ 
• Preclinical and Clinical Evidence Supporting Use of Cannabidiol in Psychiatry. (Italy/ Greece, full, 2019) https://www.hindawi.com/journals/ecam/2019/2509129/ 
• The Potential Benefits of Palmitoylethanolamide in Palliation: A Qualitative Systematic Review. (USA, link to PDF, 2019) https://www.researchgate.net/publication/333265797_The_Potential_Benefits_of_Palmitoylethanolamide_in_Palliation_A_Qualitative_Systematic_Review 
• Brain region-dependent changes in the expression of endocannabinoid-metabolizing enzymes in rats following antidepressant drugs. (Poland, link to PDF, 2019) https://www.researchgate.net/publication/338298063_Brain_region-dependent_changes_in_the_expression_of_endocannabinoid-metabolizing_enzymes_in_rats_following_antidepressant_drugs 
• Relationship of Cannabis Use to Patient-Reported Symptoms in Cancer Patients Seeking Supportive/Palliative Care. (USA, download, 2019) https://www.cannabisskunksense.co.uk/uploads/site-files/Relationship_of_cannabis_use.pdf 
• Effects of cannabidiol in males and females in two different rat models of depression. (Israel/ USA, click “researchgate” for download, 2019) https://scholar.google.com/scholar?q=%22Effects+of+cannabidiol+in+males+and+females+in+two+different+rat+models+of+depression%22&hl=en&as_sdt=0&as_vis=1&oi=scholart 
• Stimulation of Peroxisome Proliferator-Activated Receptor-α by NPalmitoylethanolamine Engages Allopregnanolone Biosynthesis to Modulate Emotional Behavior. (USA, click “researchgate” for download, 2019) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Stimulation+of+Peroxisome+Proliferator-Activated+Receptor-%CE%B1+by+N-Palmitoylethanolamine+Engages+Allopregnanolone+Biosynthesis+to+Modulate+Emotional+Behavior.%22&btnG 
• A longitudinal analysis of cannabis use and mental health symptoms among gay, bisexual, and other men who have sex with men in Vancouver, Canada. (Canada/ USA, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0165032718319293?via%3Dihub 
• Depressive Symptoms and Suicidality in Adolescents Using e-Cigarettes and Marijuana: A Secondary Data Analysis From the Youth Risk Behavior Survey. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/30688723/ 
• Anxiolytic and antidepressant effects of ACPA and harmaline co-treatment. (Iran, abstract, 2019) https://www.sciencedirect.com/science/article/pii/S0166432818316735?via%3Dihub 
• The association between substance use and depressive symptomatology in nursing university students in Mexico. (Mexico/ USA, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S1471595317306777?via%3Dihub 
• Emerging evidence for the antidepressant effect of cannabidiol and the underlying molecular mechanisms. (Brazil/Denmark, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0891061818302114?via%3Dihub 
• Patient-reported use of medical cannabis for pain, anxiety, and depression symptoms: Systematic review and meta-analysis. (USA, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0277953619303272?via%3Dihub 
• MEDICAL MARIJUANA DEPENDENCE AMONG CHRONIC PAIN PATIENTS SUFFERING FROM DEPRESSION AND ANXIETY. (Israel, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31339242/ 
• Association between history of concussion and substance use is mediated by mood disorders. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31359826/ 
• A functional variant of CB2 receptor gene interacts with childhood trauma and FAAH gene on anxious and depressive phenotypes. (Hungary/ UK, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0165032719303623?via%3Dihub 
• Repetitive high-frequency transcranial magnetic stimulation reverses depressive-like behaviors and protein expression at hippocampal synapses in chronic unpredictable stress-treated rats by enhancing endocannabinoid signaling. (China, abstract, 2019) https://www.sciencedirect.com/science/article/pii/S0091305719301376?via%3Dihub 
• Anhedonia in depression symptomatology: Appetite dysregulation and defective brain reward processing. (Italy, abstract, 2019) https://www.sciencedirect.com/science/article/pii/S0166432819303225?via%3Dihub 
• Cannabidiol (CBD) use in psychiatric disorders: A systematic review. (UK/ Italy, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0161813X19300774?via%3Dihub 
• Plasma concentrations of oleoylethanolamide in a primary care sample of depressed patients are increased in those treated with selective serotonin reuptake inhibitor-type antidepressants. (Spain, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0028390819300590 
• The "entourage effect": Terpenes coupled with cannabinoids for the treatment of mood disorders and anxiety disorders. (Israel, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31481004/ 
• Endocannabinoid modulation of inflammatory hyperalgesia in the IFN-α mouse model of depression. (Ireland, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0889159119306063?via%3Dihub 
• An overview of the heterogeneity of major depressive disorder: Current knowledge and Future prospective. (India, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31573890/ 
• Role of endocannabinoid system in dopamine signalling within the reward circuits affected by chronic pain. (Poland, abstract, 2019) https://www.semanticscholar.org/paper/Role-of-endocannabinoid-system-in-dopamine-within-Mlost-W%C4%85sik/8ead21c33539fa530f887472c42bec2c88969902 
• N-Palmitoylethanolamide Exerts Antidepressant-Like Effects in Rats: Involvement of PPARα Pathway in the Hippocampus. (China, abstract, 2019) https://jpet.aspetjournals.org/content/369/1/163.long 
• Nutrition and immunology in mental health: Precision medicine and integrative approaches to address unmet clinical needs in psychiatric treatments. (UK/ Taiwan, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0889159119312322?via%3Dihub 
• Role of palmitoylethanolamide (PEA) in depression: Translational evidence: Special Section on “Translational and Neuroscience Studies in Affective Disorders”. (Italy/ Canada, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0165032718315994?via%3Dihub 
• Neuropeptide Y and cannabinoids interaction in the amygdala after exposure to shock and reminders model of PTSD. (Israel/ USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31622603/ 
• Ligands of the CB2 cannabinoid receptors augment activity of the conventional antidepressant drugs in the behavioural tests in mice. (Poland, abstract, 2019) https://www.sciencedirect.com/science/article/pii/S0166432819311891?via%3Dihub 
• Cannabis use behaviors and prevalence of anxiety and depressive symptoms in a cohort of Canadian medicinal cannabis users. (Canada, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0022395618304783 
• Does cannabis use modify the effect of post-traumatic stress disorder on severe depression and suicidal ideation? Evidence from a population-based cross-sectional study of Canadians. (Canada/ USA, abstract, 2019) https://journals.sagepub.com/doi/abs/10.1177/0269881119882806?journalCode=jopa& 
• Perceived Efficacy of Medical Cannabis in the Treatment of Co-Occurring HealthRelated Quality of Life Symptoms. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31693457/ 
• Potential new therapies against a toxic relationship: neuroinflammation and Parkinson's disease. (Brazil / Spain, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31703030/ 
• Depressive symptoms and cannabis use in a placebo-controlled trial of N-Acetylcysteine for adult cannabis use disorder. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31712969/ 
• Cannabis Use in Persons With Inflammatory Bowel Disease and Vulnerability to Substance Misuse. (Canada, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31725152/ 
• The association of endocannabinoid receptor genes (CNR1 and CNR2) polymorphisms with depression: A meta-analysis. (China, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31725603/ 
• Psychological and endocannabinoid responses to aerobic exercise in substance use disorder patients. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31729933/ 
• Link between personality and response to THC exposure. (Israel, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31734264/ 
• Adverse childhood experience patterns, major depressive disorder, and substance use disorder in older adults. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31769297/ 
• Rapid increase in the prevalence of cannabis use among persons with depression in the U.S., 2005-2017: the role of differentially changing risk perceptions. (USA, abstract, 2019) https://onlinelibrary.wiley.com/doi/abs/10.1111/add.14883 
• 2018
• Medicinal cannabis use can help mitigate symptoms of PTSD, study says. (news – 2018)
  https://www.theglobeandmail.com/canada/article-medicinal-cannabis-use-can-help-mitigate-symptoms-of-ptsd-study-says/
• Veterans are left out of medical marijuana protections. (news – 2018)
  https://thehill.com/opinion/healthcare/394083-veterans-are-left-out-of-medical-marijuana-protections
• When It Comes to Medical Marijuana, Veterans Often Have to Improvise. (news – 2018)
  https://www.military.com/daily-news/2018/09/02/when-it-comes-medical-marijuana-veterans-often-have-improvise.html
• Use of Protective Behavioral Strategies among Young Adult Veteran Marijuana Users. (USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947861/ 
• Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis cohort. (Canada/ USA, full, 2018) https://link.springer.com/article/10.1186/s10194-018-0862-2 
• Detection of Significant Association Between Variants in Cannabinoid Receptor 1 Gene (CNR1) and Personality in African-American Population. (USA/ China, full, 2018) https://www.frontiersin.org/articles/10.3389/fgene.2018.00199/full 
• Negative urgency partially accounts for the relationship between major depressive disorder and marijuana problems. (USA, full, 2018) https://bpded.biomedcentral.com/articles/10.1186/s40479-018-0087-7 
• Prolonged Cannabidiol Treatment Effects on Hippocampal Subfield Volumes in Current Cannabis Users. (Australia, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908414/ 
• A naturalistic examination of the perceived effects of cannabis on negative affect. (USA, full, 2018) https://www.sciencedirect.com/science/article/pii/S0165032718303100 
• A Cross-Sectional Study of Cannabidiol Users. (USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043845/ 
• Cognitive and Mental Health Predictors of Withdrawal Severity During an Active Attempt to Cut Down Cannabis Use. (Netherlands, full, 2018) https://www.frontiersin.org/articles/10.3389/fpsyt.2018.00301/full 
• An Inflammation-Centric View of Neurological Disease: Beyond the Neuron. (Italy, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871676/ 
• The Consumption of Cannabis by Fibromyalgia Patients in Israel. (Israel, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081591/ 
• New Perspectives on the Use of Cannabis in the Treatment of Psychiatric Disorders. (Italy/ USA, full, 2018) https://www.mdpi.com/2305-6320/5/4/107/htm 
• Evaluating the Long-Term Effectiveness of School-Based Depression, Anxiety, and Substance Use Prevention Into Young Adulthood: Protocol for the Climate School Combined Study. (Australia, full, 2018) https://www.researchprotocols.org/2018/11/e11372/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+ResProtoc+%28JMIR+Research+Protocols%29 
• Mental Health Issues and Substance Use in the United States: Pulling the Power Levers. (USA, full, 2018) https://pubmed.ncbi.nlm.nih.gov/30406713/ 
• Transcriptomic Characterization of the Human Habenula Highlights Drug Metabolism and the Neuroimmune System. (Canada/ USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220030/ 
• Exploiting the Multifaceted Effects of Cannabinoids on Mood to Boost Their Therapeutic Use Against Anxiety and Depression. (Italy, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256035/ 
• Marijuana Use and Depressive Symptoms; Gender Differences in African American Adolescents. (USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250838/ 
• Adult cellular neuroadaptations induced by adolescent THC exposure in female rats are rescued by enhancing anandamide signaling. (Italy, full, 2018) https://academic.oup.com/ijnp/article/21/11/1014/5047132 
• Medicinal versus Recreational Cannabis Use among Returning Veterans. (USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037171/ 
• Adolescent THC exposure in female rats leads to cognitive deficits through a mechanism involving chromatin modifications in the prefrontal cortex. (Italy, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837889/ 
• Substance Use and Suicide in Pacific Islander, American Indian, and Multiracial Youth. (USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706273/ 
• The role of depressive symptoms in treatment of adolescent cannabis use disorder with N-Acetylcysteine. (USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082384/ 
• The Effect of Age of Initiation of Cannabis Use on Psychosis, Depression, and Anxiety among Youth under 25 Years. (Canada, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591882/ 
• Supporting Transgender and Gender Diverse Youth: Protection Against Emotional Distress and Substance Use. (USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501838/ 
• Cannabinoids prevent depressive-like symptoms and alterations in BDNF expression in a rat model of PTSD. (Israel, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294292/ 
• Psychological Functioning of Women Taking Illicit Drugs during Pregnancy and the Growth and Development of Their Offspring in Early Childhood. (USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202263/ 
• Itch and psyche: psychiatric aspects of pruritus. (USA, full, 2018) https://onlinelibrary.wiley.com/doi/full/10.1111/ijd.14081 
• Risks and Benefits of Marijuana Use: A National Survey of U.S. Adults. (USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157909/ 
• Sex Differences in the Association Between Cannabis Use and Suicidal Ideation and Attempts, Depression, and Psychological Distress Among Canadians. (Canada, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591888/ 
• Characteristics and Patterns of Marijuana Use in Community-Dwelling Older Adults. (USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476562/ 
• Integrating endocannabinoid signaling in the regulation of anxiety and depression. (China/ Canada, full, 2018) https://www.nature.com/articles/s41401-018-0051-5 
• Cannabis Essential Oil: A Preliminary Study for the Evaluation of the Brain Effects. (Italy, link to full, 2018) https://www.hindawi.com/journals/ecam/2018/1709182/ 
• Prospects of Cannabidiol for Easing Status Epilepticus-Induced Epileptogenesis and Related Comorbidities. (USA/ India/ Brazil, link to PDF, 2018) https://www.researchgate.net/publication/322709612_Prospects_of_Cannabidiol_for_Easing_Status_Epilepticus-Induced_Epileptogenesis_and_Related_Comorbidities 
• Antidepressant-like effect induced by Cannabidiol is dependent on brain serotonin levels. (Brazil, link to PDF, 2018) https://www.researchgate.net/publication/325611730_Antidepressant-like_effect_induced_by_Cannabidiol_is_dependent_on_brain_serotonin_levels 
• Marijuana use during and after pregnancy and association of prenatal use on birth outcomes: A population-based study. (USA, link to PDF, 2018) https://www.researchgate.net/publication/324093683_Marijuana_use_during_and_after_pregnancy_and_association_of_prenatal_use_on_birth_outcomes_A_population-based_study 
• Relationships between substance abuse/dependence and psychiatric disorders based on polygenic scores. (Spain, link to PDF, 2018) https://www.semanticscholar.org/paper/Associations-between-Polygenic-Risk-for-Psychiatric-Carey-Agrawal/7efd0879f4a8da6a6043f52cdf2dcb1dbe4958b7 
• Trajectories of alcohol and marijuana use among primary versus secondary psychopathy variants within an adjudicated adolescent male sample. (USA, link to PDF, 2018) https://www.researchgate.net/publication/326856425_Trajectories_of_Alcohol_and_Marijuana_Use_Among_Primary_Versus_Secondary_Psychopathy_Variants_Within_an_Adjudicated_Adolescent_Male_Sample 
• Association of Cannabis With Long-Term Clinical Symptoms in Anxiety and Mood Disorders: A Systematic Review of Prospective Studies. (Canada/ Israel, link to PDF, 2018) https://www.researchgate.net/publication/325589498_Association_of_Cannabis_With_Long-Term_Clinical_Symptoms_in_Anxiety_and_Mood_Disorders_A_Systematic_Review_of_Prospective_Studies 
• The endocannabinoid system in mental disorders: Evidence from human brain studies. (Spain, link to PDF, 2018) https://www.researchgate.net/publication/326451892_The_endocannabinoid_system_in_mental_disorders_Evidence_from_human_brain_studies 
• Impacts of cannabinoid receptor ligands on nicotine- and chronic mild stress-induced cognitive and depression-like effects in mice. (Poland, link to download, 2018) https://isiarticles.com/bundles/Article/pre/pdf/154964.pdf 
• Developmental pathways of adolescent cannabis use: Risk factors, outcomes and sex-specific differences. (USA, click “researchgate” for download, 2018) https://www.researchgate.net/publication/328767762_Developmental_pathways_of_adolescent_cannabis_use_Risk_factors_outcomes_and_sex-specific_differences 
• Maternal separation increases alcohol-drinking behaviour and reduces endocannabinoid levels in the mouse striatum and prefrontal cortex. (Spain, click “upf” for download, 2018) https://repositori.upf.edu/bitstream/handle/10230/35712/portero-ene-mate.pdf?sequence=1&isAllowed=y 
• Developmental sensitivity to cannabis use patterns and risk for major depressive disorder in mid-life: findings from 40 years of follow-up. (UK, full, 2018) https://eprints.kingston.ac.uk/id/eprint/40172/1/Theobald-D-40172-AAM.pdf 
• Cannabidiol Induces Rapid and Sustained Antidepressant-Like Effects Through Increased BDNF Signaling and Synaptogenesis in the Prefrontal Cortex. (Brazil/ Denmark, full, 2018) https://www.drperlmutter.com/wp-content/uploads/2018/12/CBD-BDNF.pdf 
• CB1 cannabinoid receptor ligands augment the antidepressant-like activity of biometals (magnesium and zinc) in the behavioural tests. (Poland, abstract, 2018) https://pubmed.ncbi.nlm.nih.gov/29380383/ 
• Impaired glucocorticoid-mediated HPA axis negative feedback induced by juvenile social isolation in male rats. (Italy, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0028390818300510 
• Functional effects of synthetic cannabinoids versus Δ9 -THC in mice on body temperature, nociceptive threshold, anxiety, cognition, locomotor/exploratory parameters and depression. (Israel, abstract, 2018) https://www.semanticscholar.org/paper/Functional-effects-of-synthetic-cannabinoids-versus-Schreiber-Bader/bdcc732eca01fb98bf65981d65180ad3c9839dd5 
• Cannabinoid Receptors, Mental Pain and Suicidal Behavior: a Systematic Review. (Spain/ USA, abstract, 2018) https://www.semanticscholar.org/paper/Cannabinoid-Receptors%2C-Mental-Pain-and-Suicidal-a-Colino-Herranz-Herrer/aa390e07cd21931ef32b3b141ae8b22a8a50e400 
• Reduced levels of the endocannabinoid arachidonylethanolamide (AEA) in hair in patients with borderline personality disorder - a pilot study. (Germany, abstract, 2018) https://pubmed.ncbi.nlm.nih.gov/29546791/ 
• The association between lifetime cannabis use and dysthymia across six birth decades. (Israel/ Canada/ USA, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0165032717324369 
• Circulating endocannabinoids and affect regulation in human subjects. (USA/ Canada, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0306453017315470 
• Inhibition of Fatty Acid Amide Hydrolase Improves Depressive-Like Behaviors Independent of Its Peripheral Antinociceptive Effects in a Rat Model of Neuropathic Pain. (China, abstract, 2018) https://pubmed.ncbi.nlm.nih.gov/29863609/ 
• The relationship of endocannabinoidome lipid mediators with pain and psychological stress in women with fibromyalgia – a case control study. (Sweden, abstract, 2018) https://www.jpain.org/article/S1526-5900(18)30197-4/fulltext 
• Effects of rTMS on Hippocampal Endocannabinoids and Depressive-like Behaviors in Adolescent Rats. (China, abstract, 2018) https://link.springer.com/article/10.1007/s11064-018-2591-y 
• Orbitofrontal connectivity is associated with depression and anxiety in marijuana-using adolescents. (USA, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0165032718300557 
• Cannabinoids in depressive disorders. (Poland, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0024320518306040?via%3Dihub 
• Interrelationships among depression, anxiety, flourishing, and cannabis use in youth. (Canada, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0306460318304301 
• Predictors of drug use during pregnancy: The relative effects of socioeconomic, demographic, and mental health risk factors. (Canada, abstract, 2018) https://content.iospress.com/articles/journal-of-neonatal-perinatal-medicine/npm1814 
• 2017
• 10 Types of Marijuana That’ll Make You More Optimistic (news–2017) https://thefreshtoast.com/cannabis/10-types-of-marijuana-thatll-make-you-more-optimistic/#sthash.Dn5m1bN9.dpuf
• A Veteran Returned Home With PTSD And Pain, So He Became A Medical Marijuana Patient (news–2017) http://www.huffingtonpost.com/entry/leo-bridgewater-medical-marijuana-vets-ptsd_us_58fe630fe4b018a9ce5dd083
• CBD Oil Actually Helped With My Anxiety (news–2017) http://nymag.com/thecut/2017/04/what-cannabidiol-oil-did-for-me.html
• A Mother With Stage 4 Colon Cancer: How Marijuana Helped (news–2017) https://thefreshtoast.com/cannabis/a-mother-with-stage-4-colon-cancer-how-marijuana-helped/#sthash.wTX7QKIa.dpuf
• Natural chemical helps brain adapt to stress (news–2017) https://www.sciencedaily.com/releases/2017/03/170329140945.htm
• How marijuana edibles keeps this guy focused and working (news–2017) http://www.salon.com/2017/05/07/how-marijuana-edibles-keeps-this-guy-focused-and-working_partner-2/
• Cannabis is an Effective Treatment for PTSD (news–2017) https://www.marijuanatimes.org/cannabis-is-an-effective-treatment-for-ptsd/
• Changes in the Brain Endocannabinoid System in Rat Models of Depression. (Poland, full, 2017) https://link.springer.com/article/10.1007/s12640-017-9708-y 
• Palmitoylethanolamide Reduces Neuropsychiatric Behaviors by Restoring Cortical Electrophysiological Activity in a Mouse Model of Mild Traumatic Brain Injury. (USA, full, 2017) https://www.frontiersin.org/articles/10.3389/fphar.2017.00095/full 
• Endocannabinoid signalling modulates susceptibility to traumatic stress exposure. (USA, full, 2017) https://www.nature.com/articles/ncomms14782 
• Plastic and Neuroprotective Mechanisms Involved in the Therapeutic Effects of Cannabidiol in Psychiatric Disorders. (Brazil/ Spain/ USA, full, 2017) https://www.frontiersin.org/articles/10.3389/fphar.2017.00269/full 
• Residential Mobility, Transience, Depression, and Marijuana Use Initiation Among Adolescents and Young Adults. (USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457171/ 
• Adolescent Exposure to the Synthetic Cannabinoid WIN 55212-2 Modifies Cocaine Withdrawal Symptoms in Adult Mice. (Spain, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486147/ 
• Cannabis as a substitute for prescription drugs - a cross-sectional study. (USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422566/ 
• Abnormalities in Dynamic Brain Activity Caused by Mild Traumatic Brain Injury Are Partially Rescued by the Cannabinoid Type-2 Receptor Inverse Agonist SMM-189. (USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562300/ 
• Targeting the Endocannabinoid/CB1 Receptor System For Treating Major Depression Through Antidepressant Activities of Curcumin and Dexanabinol-Loaded Solid Lipid Nanoparticles. (China, full, 2017) https://www.karger.com/Article/FullText/480001 
• An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies. (Germany, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569602/ 
• Effects of cannabis use and subclinical depression on the P3 event-related potential in an emotion processing task. (USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371467/ 
• Selectively Impaired Endocannabinoid-Dependent Long-Term Depression in the Lateral Habenula in an Animal Model of Depression. (Republic of Korea, full, 2017) https://www.sciencedirect.com/science/article/pii/S221112471730863X 
• Cannabinoid type 2 receptors in dopamine neurons inhibits psychomotor behaviors, alters anxiety, depression and alcohol preference. (USA/ Japan/ Brazil, full, 2017) https://www.nature.com/articles/s41598-017-17796-y 
• Schizophrenia and depression, two poles of endocannabinoid system deregulation. (Spain, full, 2017) https://www.nature.com/articles/s41398-017-0029-y 
• Cannabinoid Modulation of the Stressed Hippocampus. (Brazil, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742214/ 
• Use of ketamine for acute suicidal ideation in a patient with chronic pain on prescribed cannabinoids. (USA, full, 2017) https://casereports.bmj.com/content/2017/bcr-2017-222059.long 
• Associations of anxiety sensitivity and emotional symptoms with the subjective effects of alcohol, cigarettes, and cannabis in adolescents. (USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515287/ 
• Examination of cumulative effects of early adolescent depression on cannabis and alcohol use disorder in late adolescence in a community-based cohort. (USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633491/ 
• Mechanisms Underlying Sex Differences in Cannabis Use. (USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828236/ 
• Prolonged cannabis withdrawal in young adults with lifetime psychiatric illness. (USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572754/ 
• Nucleus Accumbens Functional Connectivity at Age 20 is Associated with Trajectory of Adolescent Cannabis Use and Predicts Psychosocial Functioning in Young Adulthood. (USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633503/ 
• Chronic CB1 cannabinoid receptor antagonism persistently increases dendritic spine densities in brain regions important to zebra finch vocal learning and production in an antidepressant-sensitive manner. (USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661891/ 
• Adolescent peer networks and the moderating role of depressive symptoms on developmental trajectories of cannabis use. (USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614846/ 
• Amplification of mGlu5-endocannabinoid signaling rescues behavioral and synaptic deficits in a mouse model of adolescent and adult dietary polyunsaturated fatty acids imbalance. (France, full, 2017) https://www.jneurosci.org/content/37/29/6851.full 
• Effects of extended cannabis abstinence on clinical symptoms in cannabis dependent schizophrenia patients versus non-psychiatric controls. (Canada, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603819/ 
• Integrating Endocannabinoid Signaling and Cannabinoids into the Biology and Treatment of Posttraumatic Stress Disorder. (USA/ Canada/ Italy, full, 2017) https://www.nature.com/articles/npp2017162 
• The effects of synthetic cannabinoids on executive function. (Israel/ Hungary, link to PDF, 2017) https://www.researchgate.net/publication/313320166_The_effects_of_synthetic_cannabinoids_on_executive_function 
• Endocannabinoid and Mood Responses to Exercise in Adults with Varying Activity Levels. (USA, link to PDF, 2017) https://www.researchgate.net/publication/315436386_Endocannabinoid_and_Mood_Responses_to_Exercise_in_Adults_with_Varying_Activity_Levels 
• Emotional disorders induced by Hemopressin and RVD-hemopressin(α) administration in rats. (Italy/ Hungary, link to PDF, 2017) https://www.researchgate.net/publication/317858765_Emotional_disorders_induced_by_Hemopressin_and_RVD-hemopressina_administration_in_rats 
• Antibiotic-induced microbiota perturbation causes gut endocannabinoidome changes, hippocampal neuroglial reorganization and depression in mice. (Italy, link to PDF, 2017) https://www.researchgate.net/publication/319590700_Antibiotic-induced_microbiota_perturbation_causes_gut_endocannabinoidome_changes_hippocampal_neuroglial_reorganization_and_depression_in_mice 
• Cannabis use and mental health-related quality of life among individuals with depressive disorders. (Israel/ Germany/ Canada, download, 2017) https://isiarticles.com/bundles/Article/pre/pdf/60067.pdf 
• Role of orbitofrontal sulcogyral pattern on lifetime cannabis use and depressive symptoms. (Australia/ Netherlands/ Spain/ UK, click “uow” for download, 2017) https://ro.uow.edu.au/cgi/viewcontent.cgi?article=4143&context=sspapers 
• Is cannabis treatment for anxiety, mood, and related disorders ready for prime time? (Canada, click “therocus” for download, 2017) https://onlinelibrary.wiley.com/doi/abs/10.1002/da.22664 
• User characteristics and effect profile of Butane Hash Oil: An extremely high-potency cannabis concentrate. (Australia/ UK, full, 2017)  https://discovery.ucl.ac.uk/id/eprint/1563617/1/Freeman_Chan%20et%20al.%202017.pdf 
• Activation of cannabinoid receptors elicits antidepressant-like effects in a mouse model of social isolation stress. (Iran, full, 2017) http://eprints.skums.ac.ir/169/1/1-s2.0-S0361923016303100-main.pdf 
• Role of the endocannabinoid system in the formation and development of depression. (China, click “ingentaconnectcom” for download, 2017) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Role+of+the+endocannabinoid+system+in+the+formation+and+development+of+depression.%22&btnG 
• Role of cannabinoid receptor 1-mediated synaptic plasticity in neuropathic pain and associated depression. (China, abstract, 2017) https://pubmed.ncbi.nlm.nih.gov/28364110/ 
• Cannabis Use and Risk for Substance Use Disorders and Mood or Anxiety Disorders. (USA, abstract, 2017) https://jamanetwork.com/journals/jama/article-abstract/2610319 
• FAAH Inhibition Produces Antidepressant-like efforts of Mice to Acute Stress via Synaptic Long-term Depression. (Canada/ China, abstract, 2017) https://www.semanticscholar.org/paper/FAAH-inhibition-produces-antidepressant-like-of-to-Wang-Zhang/96fbdee29bffa8d030b4d8f8e386d4b059ba69c4 
• Associations between substance use disorders and suicide or suicide attempts in people with mental illness: A Danish nationwide, prospective, register-based study of patients diagnosed with schizophrenia, bipolar disorder, unipolar depression or personality disorder. (Denmark, abstract, 2017) https://onlinelibrary.wiley.com/doi/abs/10.1111/add.13788 
• Cannabinoids as therapeutic for PTSD. (USA, abstract, 2017) https://www.sciencedirect.com/science/article/pii/S2352250X16302342 
• Electroconvulsive therapy enhances endocannabinoids in the cerebrospinal fluid of patients with major depression: a preliminary prospective study. (Germany, abstract, 2017) https://www.semanticscholar.org/paper/Electroconvulsive-therapy-enhances-endocannabinoids-Kranaster-Hoyer/54805dc0791bf9c61590fdc9dc30b9a2f7b3ad96 
• Prefrontal endocannabinoids, stress controllability and resilience: A hypothesis. (USA/ Canada, abstract, 2017) https://www.sciencedirect.com/science/article/abs/pii/S0278584616302470?via%3Dihub 
• Properties of the corticostriatal long term depression induced by medial prefrontal cortex high frequency stimulation in vivo. (Argentina, abstract, 2017) https://www.sciencedirect.com/science/article/abs/pii/S0028390817301971 
• Interferon-γ causes mood abnormalities by altering cannabinoid CB1 receptor function in the mouse striatum. (Italy, abstract, 2017) https://www.sciencedirect.com/science/article/abs/pii/S0969996117301717?via%3Dihub 
• CHANGES IN THE CANNABINOIDS RECEPTORS IN RATS FOLLOWING TREATMENT WITH ANTIDEPRESSANTS. (Poland, abstract, 2017) https://www.sciencedirect.com/science/article/abs/pii/S0161813X17301717 
• Depression and anxiety among chronic pain patients receiving prescription opioids and medical marijuana. (Israel, abstract, 2017) https://www.sciencedirect.com/science/article/abs/pii/S0165032716320018?via%3Dihub 
• 2016
• Marijuana Could Help Treat Drug Addiction and Mental Health Problems (news & abst–2016) http://neurosciencenews.com/addiction-mental-health-marijuana-5536/
• Treating Depression in Alcoholics (news & abst–2016) http://neurosciencenews.com/alcoholism-depression-psychology-3541/
• Cannabis Compares Favorably to Conventional PTSD Treatments (news–2016) http://www.prweb.com/releases/2016/03/prweb13244763.htm
• Smoking cannabis DOESN’T cause clinical anxiety or depression, study finds (news–2016) http://www.dailymail.co.uk/news/article-3456326/Smoking-cannabis-DOESN-T-cause-clinical-anxietydepression.html#ixzz45lywpZ11
• An elderly couple found help for a brain injury through marijuana – then police found 20 pot plants growing at their home (news–2016) http://www.nashvillescene.com/nashville/an-elderly-couple-found-help-for-a-brain-injury-throughmarijuana-andmdash-then-police-found-20-pot-plants-growing-at-their-home/Content?oid=6798313
• Marijuana Appears to Benefit Mental Health: Study (news–2016) http://time.com/4573129/marijuana-cannabis-mental-health/
• Cyclooxygenase-2 inhibition reduces stress-induced affective pathology. (USA, full, 2016) https://elifesciences.org/articles/14137 
• Putative Epigenetic Involvement of the Endocannabinoid System in Anxiety- and Depression-Related Behaviors Caused by Nicotine as a Stressor. (Japan, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942073/ 
• Fluorinated Cannabidiol Derivatives: Enhancement of Activity in Mice Models Predictive of Anxiolytic, Antidepressant and Antipsychotic Effects. (Israel/ Brazil, full, 2016) https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0158779 
• Endocannabinoid-Mediated Plasticity in Nucleus Accumbens Controls Vulnerability to Anxiety after Social Defeat Stress. (France, full, 2016) https://www.cell.com/cell-reports/fulltext/S2211-1247(16)30851-8 
• The relationship between cannabis use and measures of anxiety and depression in a sample of college campus cannabis users and non-users post state legalization in Colorado. (USA, full, 2016) https://peerj.com/articles/2782/ 
• Ketamine and MAG Lipase Inhibitor-Dependent Reversal of Evolving Depressive Behavior during Forced Abstinence from Alcohol Drinking. (USA, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908652/ 
• Lipids in psychiatric disorders and preventive medicine. (Germany/ USA, full, 2016) https://www.sciencedirect.com/science/article/pii/S0149763415303353 
• The association of specific traumatic experiences with cannabis initiation and transition to problem use: Differences between African-American and European-American women. (USA, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833569/ 
• Target-specific modulation of the descending prefrontal cortex inputs to the dorsal raphe nucleus by cannabinoids. (USA/ Canada, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868450/ 
• Endocannabinoid system: Role in depression, reward and pain control (Review). (China, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042796/ 
• Bidirectional Associations Between Cannabis Use and Depressive Symptoms From Adolescence Through Early Adulthood Among At-Risk Young Men. (USA, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803661/ 
• Dose-dependent cannabis use, depressive symptoms, and FAAH genotype predict sleep quality in emerging adults: a pilot study. (USA, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289074/ 
• Splendor in the Grass? A Pilot Study Assessing the Impact of Medical Marijuana on Executive Function. (USA, full, 2016) https://www.frontiersin.org/articles/10.3389/fphar.2016.00355/full 
• Beyond the CB1 Receptor: Is Cannabidiol the Answer for Disorders of Motivation? (USA, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818147/ 
• Comparing adults who use cannabis medically with those who use recreationally: Results from a national sample. (USA, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915997/ 
• The genetic basis of the comorbidity between cannabis use and major depression. (USA, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148647/ 
• Genetically reduced FAAH activity may be a risk for the development of anxiety and depression in persons with repetitive childhood trauma. (Hungary, full, 2016) https://www.sciencedirect.com/science/article/pii/S0924977X16000778 
• Sevoflurane Prevents Stroke-induced Depressive and Anxiety Behaviors by Promoting Cannabinoid Receptor Subtype I-dependent Interaction Between β-Arrestin 2 and ERK1/2 in the Rat Hippocampus. (China, full, 2016) https://onlinelibrary.wiley.com/doi/full/10.1111/jnc.13613 
• Pharmacological inhibition of FAAH activity in rodents: a promising pharmacological approach for psychological - cardiac comorbidity? (Italy/ Australia/ USA, link to PDF, 2016) https://www.researchgate.net/publication/301734639_Pharmacological_inhibition_of_FAAH_activity_in_rodents_A_promising_pharmacological_approach_for_psychological-cardiac_comorbidity 
• The endocannabinoid system and NGF are involved in the mechanism of action of resveratrol: a multi-target nutraceutical with therapeutic potential in neuropsychiatric disorders. (Iran, link to PDF, 2016) https://www.researchgate.net/publication/291185238_The_endocannabinoid_system_and_NGF_are_involved_in_the_mechanism_of_action_of_resveratrol_A_multi-target_nutraceutical_with_therapeutic_potential_in_neuropsychiatric_disorders 
• Cannabidiol, neuroprotection and neuropsychiatric disorders. (Brazil, link to download, 2016) https://static1.squarespace.com/static/57faf399cd0f68a69b4c670c/t/5839e5e4e58c622c253519e9/1480189413826/Cannabidiol%2C+neuroprotection+and+neuropsychiatric+disorders.pdf 
• Potential Biomarkers for Depression Associated with Coronary Artery Disease: A Critical Review. (Canada, link to download, 2016) https://www.eurekaselect.com/138787/article 
• Cannabidiol reduces neuroinflammation and promotes neuroplasticity and functional recovery after brain ischemia. (Brazil, click “researchgate” for download, 2016) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Cannabidiol+reduces+neuroinflammation+and+promotes+neuroplasticity+and+functional+recovery+after+brain+ischemia%22&btnG 
• Medical cannabis and mental health: A guided systematic review. (Canada/ USA, click “ubcca” for download, 2016) http://blogs.ubc.ca/walshlab/files/2015/06/Review-Article.pdf 
• The Anxiolytic Actions of 2-Arachidonoylglycerol: Converging Evidence From Two Recent Genetic Endocannabinoid Deficiency Models. (USA, 1st page, 2016) https://www.biologicalpsychiatryjournal.com/article/S0006-3223(15)00532-6/fulltext 
• Role of hypothalamic cannabinoid receptors in post-stroke depression in rats. (China, abstract, 2016) https://www.sciencedirect.com/science/article/abs/pii/S0361923016300065 
• Antidepressant-like effect of cannabidiol injection into the ventral medial prefrontal cortex – possible involvement of 5-HT1A and CB1 receptors. (Brazil, abstract, 2016) https://www.sciencedirect.com/science/article/pii/S0166432816300298 
• Anandamide reverses depressive-like behavior, neurochemical abnormalities and oxidative-stress parameters in streptozotocin-diabetic rats: Role of CB1 receptors. (Brazil, abstract, 2016) https://www.sciencedirect.com/science/article/abs/pii/S0924977X1630164X 
• Sex and age specific effects of delta-9-tetrahydrocannabinol during the periadolescent period in the rat: The unique susceptibility of the prepubescent animal. (USA, abstract, 2016) https://www.sciencedirect.com/science/article/abs/pii/S0892036216300101?via%3Dihub 
• Gender Differences in Associations Between Attention-Deficit/Hyperactivity Disorder and Substance Use Disorder. (Denmark/Norway, abstract, 2016) https://www.semanticscholar.org/paper/Gender-Differences-in-Associations-Between-Disorder-Ottosen-Petersen/86e5674b13ccbccc152be48f60a96762f9d50c24 
• Exercise deprivation increases negative mood in exercise-addicted subjects and modifies their biochemical markers. (Brazil, abstract, 2016) https://www.sciencedirect.com/science/article/abs/pii/S0031938416300269 
• Medical marijuana use in head and neck squamous cell carcinoma patients treated with radiotherapy. (USA, abstract, 2016) https://www.redjournal.org/article/S0360-3016(14)02729-1/fulltext 
• Prohedonic Effect of Cannabidiol in a Rat Model of Depression. (Israel/ USA, abstract, 2016) https://www.semanticscholar.org/paper/Prohedonic-Effect-of-Cannabidiol-in-a-Rat-Model-of-Shoval-Shbiro/c0e3c58433e19601581b85347d747a449f687844 
• Anxiety, depression and risk of cannabis use: Examining the internalising pathway to use among Chilean adolescents. (Australia/ UK, abstract, 2016) https://www.sciencedirect.com/science/article/abs/pii/S0376871616301806 
• Contribution of health motive to cannabis use among high-school students. (France, abstract, 2016) https://www.sciencedirect.com/science/article/abs/pii/S0306460316302829 
• Chronic stress leads to epigenetic dysregulation of neuropeptide-Y and cannabinoid CB1 receptor in the mouse cingulate cortex. (Germany, abstract, 2016) https://www.sciencedirect.com/science/article/abs/pii/S0028390816304580 
• Chronic FAAH inhibition during nicotine abstinence alters habenular CB1 receptor activity and precipitates depressive-like behaviors. (France/ Italy, abstract, 2016) https://www.sciencedirect.com/science/article/abs/pii/S0028390816304579 
• Targeting the Endocannabinoid System in Psychiatric Illness. (Canada, abstract, 2016) https://pubmed.ncbi.nlm.nih.gov/27811555/ 
• Sex-dependent influence of chronic mild stress (CMS) on voluntary alcohol consumption; study of neurobiological consequences. (Spain, abstract, 2016) https://www.sciencedirect.com/science/article/pii/S0091305716302465 
• Attitudes to cannabis and patterns of use among Canadians with multiple sclerosis. (Canada, abstract, 2016) https://www.msard-journal.com/article/S2211-0348(16)30171-7/fulltext 
• A dual inhibitor of FAAH and TRPV1 channels shows dose-dependent effect on depression-like behaviour in rats. (Denmark/ Brazil, abstract, 2016) https://pubmed.ncbi.nlm.nih.gov/27938441/ 

• Cannabis use and the course and outcome of major depressive disorder: A population based longitudinal study. (Israel, Germany, Canada, abstract, 2016) https://www.sciencedirect.com/science/article/abs/pii/S0165178116311878 

• Signaling pathways to and from the hypophysial pars tuberalis, an important center for the control of seasonal rhythms. (Germany, abstract, 2016) https://www.sciencedirect.com/science/article/pii/S0016648017302320?via%3Dihub 
• 2015
• Cannabinoid Receptors May Control Aversive Memories (news & abstract-2015) http://neurosciencenews.com/habenula-cb1-receptors-memory-2742/
• New Study Finds Marijuana To Be Effective Against Depression (news–2015) http://www.huffingtonpost.com/2015/02/06/marijauna-depression_n_6622126.html
• Here’s What Marijuana Does to Your Stress (news–2015) http://www.attn.com/stories/855/marijuana-depression-research-mental-health
• 5 Prescription Drugs That Could Literally Replaced by Marijuana (news–2015) http://blogs.naturalnews.com/5-prescription-drugs-literally-replaced-marijuana/
• Teen marijuana use not linked to later depression, lung cancer, other health problems, study finds (news–2015)  http://www.sciencedaily.com/releases/2015/08/150804093718.htm
  Former U.S. Marine starts campaign to raise awareness of overmedication of veterans (news–2015) http://globalnews.ca/news/2065096/former-u-s-marine-starts-campaign-to-raise-awareness-of-overmedication-of-veterans/
• Blockade of 2-arachidonoylglycerol hydrolysis produces antidepressant-like effects and enhances adult hippocampal neurogenesis and synaptic plasticity. (USA/ China, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517601/ 
• High Times for Painful Blues: The Endocannabinoid System in Pain-Depression Comorbidity. (Ireland, full, 2015) https://academic.oup.com/ijnp/article/19/3/pyv095/2910048 
• Crosstalk between endocannabinoid and immune systems: a potential dysregulation in depression? (UK, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828487/ 
• Chronic Adolescent Marijuana Use as a Risk Factor for Physical and Mental Health Problems in Young Adult Men. (USA, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586320/ 
• Circulating endocannabinoids during hematopoietic stem cell transplantation: A pilot study. (USA, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476410/ 
• Mechanisms of stress in the brain. (USA, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933289/ 
• Cannabis use, depression and anxiety: A 3-year prospective population-based study. (Sweden, full, 2015) https://www.sciencedirect.com/science/article/pii/S0165032715310302 
• Endocannabinoid Modulation of Predator Stress-Induced Long-Term Anxiety in Rats. (USA/ Italy, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793117/ 
• Habenular CB1 Receptors Control the Expression of Aversive Memories. (France/ China, full, 2015) https://www.cell.com/neuron/fulltext/S0896-6273(15)00729-1 
• Sex-dependence of anxiety-like behavior in cannabinoid receptor 1 (Cnr1) knockout mice. (USA, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724469/ 
• Inhibitors of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase: New Targets for Future Antidepressants. (Japan, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759315/ 
• Maternal age and trajectories of cannabis use. (USA, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633363/ 
• Antidepressant-like activity and cardioprotective effects of fatty acid amide hydrolase inhibitor URB694 in socially stressed Wistar Kyoto rats. (Italy, link to download, 2015) https://www.academia.edu/22102103/Antidepressant_like_activity_and_cardioprotective_effects_of_fatty_acid_amide_hydrolase_inhibitor_URB694_in_socially_stressed_Wistar_Kyoto_rats
• Cannabidiol induces rapid-acting antidepressant-like effects and enhances cortical 5- HT/glutamate neurotransmission: role of 5-HT1A receptors. (Spain, link to download, 2015) https://www.alchimiaweb.com/blogfr/wp-content/uploads/2016/06/Cannabidiol-induces-rapid-acting-antidepressant-like-effects-and-enhances-cortical-5-HT-glutamate-neurotransmission-Role-of-5-HT1A-receptors-LINGE-NP-2016.pdf 
• For whom the endocannabinoid tolls: Modulation of innate immune function and implications for psychiatric disorders. (Ireland, click “academia” for download, 2015) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=For+whom+the+endocannabinoid+tolls%3A+Modulation+of+innate+immune+function+and+implications+for+psychiatric+disorders.&btnG 
• Involvement of norepinephrine and serotonin system in antidepressant-like effects of oleoylethanolamide in the mice models of behavior despair. (China, abstract, 2015) https://www.sciencedirect.com/science/article/abs/pii/S0304394015002049 
• Differential proteomic analysis of the anti-depressive effects of oleamide in a rat chronic mild stress model of depression. (China, abstract, 2015) https://www.sciencedirect.com/science/article/pii/S0091305715000283 
• The potential of inhibitors of endocannabinoid metabolism as anxiolytic and antidepressive drugs-A practical view. (Sweden, abstract, 2015) https://pubmed.ncbi.nlm.nih.gov/25791296/ 
• Antidepressant-like effects of the cannabinoid receptor ligands in the forced swimming test in mice: Mechanism of action and possible interactions with cholinergic system. (Poland, abstract, 2015) https://www.sciencedirect.com/science/article/pii/S0166432815000789?via%3Dihub 
• Antidepressant-like Effects of Oleoylethanolamide in a Mouse Model of Chronic Unpredictable Mild Stress. (Republic of Korea/ China, link to PDF, 2015) https://www.researchgate.net/publication/276440137_Antidepressant-like_effects_of_oleoylethanolamide_in_a_mouse_model_of_chronic_unpredictable_mild_stress 
• Smoke Your Troubles Away: Exploring the Effects of Death Cognitions on Cannabis Craving and Consumption. (Israel, abstract, 2015) https://www.safetylit.org/citations/index.php?fuseaction=citations.viewdetails&citationIds%5b%5d=citjournalarticle_483021_13 
• The endocannabinoid system role in the pathogenesis of obesity and depression. (Poland, abstract in English & Polish, 2015) http://medpress.com.pl/pubmed.php?article=22961 
• A cannabinoid receptor 1 polymorphism is protective against major depressive disorder in methadone-maintained outpatients. (France, abstract, 2015) https://www.semanticscholar.org/paper/A-cannabinoid-receptor-1-polymorphism-is-protective-Icick-Peoc%E2%80%99h/9b80448d11e7fa112c7f5ffab2ed1a474e76df79 
• Involvement of opioid system in antidepressant-like effect of the cannabinoid CB1 receptor inverse agonist AM-251 after physical stress in mice. (Iran, abstract, 2015) https://pubmed.ncbi.nlm.nih.gov/26609670/ 
• The fatty acid amide hydrolase inhibitor URB597 modulates serotonin-dependent emotional behaviour, and serotonin1A and serotonin2A/C activity in the hippocampus. (Canada/ Italy, abstract, 2015) https://www.sciencedirect.com/science/article/abs/pii/S0924977X15004101?via%3Dihub 
• Mediating processes between stress and problematic marijuana use. (USA, abstract, 2015) https://www.sciencedirect.com/science/article/abs/pii/S0306460315000167   
• 2014
• Activating cannabinoid brain receptors could replace marijuana for anxiety treatment (news–2014) http://www.medicalnewstoday.com/articles/286482.php
• Natural ‘high’ could avoid chronic marijuana use, Vanderbilt study finds (news–2014) http://news.vanderbilt.edu/2014/12/natural-high-could-avoid-chronic-marijuana-use-vanderbilt-study-finds/
• 2013
• Study: THC Increases Brain Activity In Response To Positive Stimuli (news–2013) http://blog.norml.org/2013/08/27/study-thc-increases-brain-activity-in-response-to-positive-stimuli/
• This bud’s for you: Marijuana identified as a buffer against loneliness, study suggests (news–2013) http://o.canada.com/life/marijuana-can-act-as-buffer-against-loneliness-study-suggests/
• Psychological Benefits Of Marijuana Usage (news–2013)  http://mentalhealthdaily.com/2013/03/05/psychological-benefits-of-marijuana-usage/
• 2012
• Smoking Cannabis Increases Risk of Depression in the Case of Genetic Vulnerability, Study Finds (news–2012) http://www.sciencedaily.com/releases/2011/10/111010074853.htm
• How Smoking Marijuana may Help Women to Fight Nasty Symptoms of Menopause? (news–2012) http://menopause-aid.blogspot.com/2012/11/how-smoking-marijuana-may-help-women-to.html    
• 2011
• Deficiency of Dietary Omega-3 May Explain Depressive Behaviors (news-2011) http://www.thefreelibrary.com/Deficiency+of+Dietary+Omega-3+May+Explain+Depressive+Behaviors.-a0248155576
• What An Expectant Mother Eats Affects Children’s Psychology in Later Life (news–2011) http://nanopatentsandinnovations.blogspot.com/2011/01/what-expectant-mother-eats-affects.html
• A Brain Wrought Without Omega-3 (news–2011) http://www.alzforum.org/news/research-news/brain-wrought-without-omega-3
• Natural Herbs That Increase Serotonin (news–2011) http://www.livestrong.com/article/53343-natural-herbs-increase-serotonin/