MALE AND FEMALE FERTILITY and SEXUAL FUNCTION: – Leaf411

MALE AND FEMALE FERTILITY and SEXUAL FUNCTION (minimal articles on sexual behavior)

This library section may have repeat articles from other areas.

SEE: Female Sexual Health library section for specific medical issues relating to cannabis use and the female urinary/reproductive system including the vagina, uterus, fallopian tubes, ovaries, implantation and the egg.

SEE: Male Sexual Health library section for specific medical issues relating to cannabis use and the male urinary/reproductive system including the penis, scrotum, testes, epididymis, urethra, vas deferens, prostate, seminal vesicles and sperm.

2023
The Acute Exposure of Human Adult Testis Tissue to Cannabinoids THC and CBD Does not Impact Testosterone Production nor Germ Cell Lineage. https://wjmh.org/DOIx.php?id=10.5534/wjmh.220210
Marijuana improves sex and could help close 'orgasm inequality gap' between men and women, a new study indicates. https://www.marijuanamoment.net/marijuana-improves-sex-and-could-help-close-orgasm-inequality-gap-between-men-and-women-new-study-indicates/
2020
Sex, marijuana and baby booms. (USA/ Peru, abstract, 2020) https://www.sciencedirect.com/science/article/abs/pii/S0167629619301882?via%3Dihub
2019
The Relationship between Marijuana Use Prior to Sex and Sexual Function in Women. (USA, full, 2019) https://www.smoa.jsexmed.org/article/S2050-1161(19)30009-1/fulltext
Women With Endometriosis May Find Relief With Cannabis. (news – 2019) Women With Endometriosis May Find Relief With Cannabis
Love Drug: How Cannabis can enhance your Sex Life (news–2019) https://www.leafscience.com/2019/03/26/love-drug-how-cannabis-can-enhance-your-sex-life/
How Cannabis Alters Sexual Experience: A Survey of Men and Women. (Canada, full, 2019) https://www.jsm.jsexmed.org/article/S1743-6095(19)31329-3/fulltext
Effects of Cannabinoids on Female Sexual Function. (USA/ Mexico, full, 2019) https://www.sciencedirect.com/science/article/pii/S2050052119300770?via%3Dihub
Endocannabinoids Interact With the Dopaminergic System to Increase Sexual Motivation: Lessons From the Sexual Satiety Phenomenon. (Mexico, full, 2019) https://www.frontiersin.org/articles/10.3389/fnbeh.2019.00184/full
Tetrahydrocannabinol Modulates in Vitro Maturation of Oocytes and Improves the Blastocyst Rates after in Vitro Fertilization. (Spain/ Colombia, full, 2019) https://www.cellphysiolbiochem.com/Articles/000149/
Effects of Dietary Bisphenol A on the Reproductive Function of Gilthead Sea Bream (Sparus aurata) Testes. (Italy/ Greece/ Canada/ Spain, full, 2019) https://www.mdpi.com/1422-0067/20/20/5003/htm
Developmental and reproductive toxicity studies of BIA 10-2474. (USA/ Switzerland, full, 2019) https://www.sciencedirect.com/science/article/pii/S0273230019303071?via%3Dihub
Characterisation and localisation of the endocannabinoid system components in the adult human testis. (Denmark/ France, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753062/
Marijuana smoking and markers of testicular function among men from a fertility centre. (USA, abstract, 2019) https://academic.oup.com/humrep/article-abstract/34/4/715/5307080?redirectedFrom=fulltext
Synthetic cannabinoids and endometrial stromal cell fate: Dissimilar effects of JWH-122, UR-144 and WIN55,212-2. (Portugal, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0300483X18303834?via%3Dihub
Multigenerational consequences of early-life cannabinoid exposure in zebrafish. (USA, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0041008X18305805
Marijuana Use Episodes and Partner Intimacy Experiences: A Daily Report Study. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/30923794/
Mice Missing Cnr1 and Cnr2 Show Implantation Defects. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/30776303/
Marijuana smoking and outcomes of infertility treatment with assisted reproductive technologies. (USA, abstract, 2019) https://academic.oup.com/humrep/article-abstract/34/9/1818/5549505?redirectedFrom=fulltext
Anandamide targets aromatase: A breakthrough on human decidualization. (Portugal, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S1388198119301520
Effects of diisononyl phthalate (DiNP) on the endocannabinoid and reproductive systems of male gilthead sea bream (Sparus aurata) during the spawning season. (Italy/ Greece/ Canada/ Spain, abstract, 2019) https://link.springer.com/article/10.1007%2Fs00204-018-2378-6
Sexual interaction is essential for the transformation of non-copulating rats into sexually active animals by the endocannabinoid anandamide. (Mexico, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0166432818311884?via%3Dihub
Effects of synthetic (JWH-018) cannabinoids treatment on spermatogenesis and sperm function. (Turkey, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31645148/
Cannabis and Sexual Experience. (USA, abstract, 2019) https://www.jsm.jsexmed.org/article/S1743-6095(19)31822-3/fulltext
2018
The Cannabis “Shrinkage” Problem. (news – 2018)
https://prohbtd.com/the-cannabis-shrinkage-problem
Does marijuana increase sexual desire? (news – 2018)
https://www.cnn.com/2018/06/19/health/marijuana-sex-kerner/index.html
Analysis of Endocannabinoid System in Rat Testis During the First Spermatogenetic Wave. (Italy/ USA, full, 2018) https://www.frontiersin.org/articles/10.3389/fendo.2018.00269/full
Adverse Effects of Cannabis on Male Reproduction. (USA, full, 2018) https://www.eu-focus.europeanurology.com/article/S2405-4569(18)30225-6/fulltext
The effect of cannabis exposure on pubertal outcomes: a systematic review. (Canada, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181473/
Melatonin attenuates Δ9-tetrahydrocannabinol-induced reduction in rat sperm motility and kinematics in-vitro. (Rwanda/ Nigeria, PDF, 2018) https://www.researchgate.net/publication/323198133_Melatonin_attenuates_D_9_-tetrahydrocannabinol-induced_reduction_in_rat_sperm_motility_and_kinematics_in-vitro
The effects of cannabinoids on the endocrine system. (Poland, PDF, 2018) https://journals.viamedica.pl/endokrynologia_polska/article/view/58487
GPR3, GPR6, and GPR12 as novel molecular targets: their biological functions and interaction with cannabidiol. (USA, full, 2018) https://ir.library.louisville.edu/cgi/viewcontent.cgi?article=4093&context=etd
Transcriptional abundance of type-1 endocannabinoid receptor (CB1) and fatty acid amide hydrolase (FAAH) in bull spermatozoa: Relationship with field fertility. (India, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0093691X18301420
Disruption of the gonadal endocannabinoid system in zebrafish exposed to diisononyl phthalate. (Italy/ Canada, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0269749118304007
Chronic cannabidiol exposure promotes functional impairment in sexual behavior and fertility of male mice. (Brazil, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0890623818301357?via%3Dihub
Effect of chronic THC administration in the reproductive organs of male mice, spermatozoa and in vitro fertilization. (Spain/ Columbia, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0006295218303150
Effects of feeding a source of omega-3 fatty acid during the early postpartum period on the endocannabinoid system in the bovine endometrium. (Iran, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0093691X18305880?via%3Dihub
2017
This Wonderful New Weed Strain Helps Women Have Orgasms (news–2017) https://www.maxim.com/maxim-man/weed-strain-helps-women-orgasm-2017-5
6 Sexy Weed Strains That Will Make You Better In Bed (news–2017) https://www.maxim.com/maxim-man/best-strains-of-marijuana-for-sex-2017-1
Jewish backstory of sexy cannabis products for women (news–2017) http://www.jweekly.com/2017/04/13/jewish-backstory-of-sexy-cannabis-products-for-women/
Philly420: The birds, the bees and the buds (news–2017) http://www.philly.com/philly/columnists/philly420/Philly420_The_birds_the_bees_and_the_buds.html
How different types of marijuana affect your orgasms (news–2017) http://www.salon.com/2017/07/07/how-different-types-of-marijuana-affect-your-orgasms_partner/
New Cannabis Strain Designed to Help Women Orgasm (news–2017) https://www.marijuanatimes.org/new-cannabis-strain-designed-to-help-women-orgasm/
Regular marijuana users have more sex, study says (news–2017) http://www.cnn.com/2017/10/27/health/marijuana-increased-sex/index.html
Is Pot Good For Your Sex Life? The Truth About Being High and Horny (news–2017) https://www.menshealth.com/sex-women/marijuana-good-for-sex-life
Could marijuana be an aphrodisiac? (news–2017) https://www.news-medical.net/news/20171029/Could-marijuana-be-an-aphrodisiac.aspx
Endocannabinoid system in sexual motivational processes: is it a novel therapeutic horizon? (Czech Republic/ Italy, full, 2017) https://www.sciencedirect.com/science/article/abs/pii/S1043661816312385
The Roles of Anandamide, Fatty Acid Amide Hydrolase, and Leukemia Inhibitory Factor on the Endometrium during the Implantation Window. (China, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650704/
Participation of hypothalamic CB1 receptors in reproductive axis disruption during immune challenge. (Argentina, link to PDF, 2017) https://www.researchgate.net/publication/318081117_Participation_of_hypothalamic_CB1_receptors_in_reproductive_axis_disruption_during_immune_challenge
Human sperm motility, capacitation and acrosome reaction are impaired by 2- arachidonoylglycerol endocannabinoid. (Spain, link to PDF, 2017) https://www.researchgate.net/publication/317387241_Human_sperm_motility_capacitation_and_acrosome_reaction_are_impaired_by_2-arachidonoylglycerol_endocannabinoid
Anandamide oxidative metabolism-induced endoplasmic reticulum stress and apoptosis. (Portugal, abstract, 2017) https://link.springer.com/article/10.1007%2Fs10495-017-1356-4
Individual prolactin reactivity modulates response of nucleus accumbens to erotic stimuli during acute cannabis intoxication: an fMRI pilot study. (Czech Republic/ Slovak Republic, abstract, 2017) https://link.springer.com/article/10.1007/s00213-017-4601-1
Expression and distribution of key proteins of the endocannabinoid system in the human seminal vesicles. (Germany/ Italy/ USA/ Sweden, abstract, 2017) https://www.jsm.jsexmed.org/article/S1743-6095(17)31811-8/abstract
Masturbation to Orgasm Stimulates the Release of the Endocannabinoid 2- Arachidonoylglycerol in Humans. (Germany, abstract, 2017) https://www.jsm.jsexmed.org/article/S1743-6095(17)31443-1/fulltext
Incubation of spermatozoa with Anandamide prior to cryopreservation reduces cryocapacitation and improves post-thaw sperm quality in the water buffalo (Bubalus bubalis). (India, abstract, 2017) https://www.semanticscholar.org/paper/Incubation-of-spermatozoa-with-Anandamide-prior-to-Kumar-Mohanty/43878c6007d6a564153a75774e22c2c49441a8e5
Association Between Marijuana Use and Sexual Frequency in the United States: A Population-Based Study. (USA, abstract, 2017) https://www.semanticscholar.org/paper/Association-Between-Marijuana-Use-and-Sexual-in-the-Sun-Eisenberg/c7f670b6710f493d6e18bcfd019483de3ef324a3
2016
Match.com’s Recent Survey Explores The Relationship Between Singles And Weed (news–2016) http://aplus.com/a/match-survey-how-weed-affects-dating-relationships
Comparing sexual experiences related to alcohol and marijuana use among adults (news–2016) http://www.eurekalert.org/pub_releases/2016-08/nyu-cse080416.php
Tantra THC: Using Cannabis to Make Sex Sacred (news–2016) http://sfevergreen.com/tantra-thc-using-cannabis-make-sex-sacred/
Pot users twice as likely to report multiple orgasms, Match.com finds (news–2016) http://blog.sfgate.com/smellthetruth/2016/04/19/pot-users-twice-as-likely-to-report-multiple-orgasms-match-com-finds /
Cannabinoid Receptor Activates Spermatozoa (news–2016) http://neurosciencenews.com/spermatozoa-cannabinoid-receptors-4935/
Progesterone and Endocannabinoid Interaction Alters Sperm Activation. (UK, full, 2016) https://academic.oup.com/biolreprod/article/95/1/9,%201-1/2883476
Characterization of non-olfactory GPCRs in human sperm with a focus on GPR18. (Germany/ Poland, full, 2016) https://www.nature.com/articles/srep32255
Unconventional endocannabinoid signaling governs sperm activation via sex hormone progesterone. (USA, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373689/
The endocannabinoid anandamide impairs in vitro decidualization of human cells. (Portugal, full, 2016) https://rep.bioscientifica.com/view/journals/rep/152/4/351.xml
2-arachidonoylglycerol levels are increased in leukocytospermia and correlate with seminal macrophages. (Italy, full, 2016) https://onlinelibrary.wiley.com/doi/full/10.1111/andr.12283
The endocannabinoid system in the human granulosa cell line KGN. (Germany, abstract, 2016) https://www.sciencedirect.com/science/article/abs/pii/S0303720716300065
Anandamide interferes with human endometrial stromal-derived cell differentiation: An effect dependent on inhibition of cyclooxygenase-2 expression and prostaglandin E2 release. (Portugal, abstract, 2016) https://www.semanticscholar.org/paper/Anandamide-interferes-with-human-endometrial-cell-Almada-Cunha/897b490f00a1b8be00b4e25759f54e0057401163
Dynamic of expression and localization of cannabinoid-degrading enzymes FAAH and MGLL in relation to CB1 during meiotic maturation of human oocytes. (Spain, abstract, 2016) https://link.springer.com/article/10.1007%2Fs00441-016-2381-2
Intra-VTA anandamide infusion produces dose-based biphasic effects on male rat sexual behavior expression. (Mexico, abstract, 2016) https://www.sciencedirect.com/science/article/abs/pii/S0091305716302258
2015
The Cannabinoid Receptor 2 Q63R Variant Modulates the Relationship between Childhood Obesity and Age at Menarche. (Italy/ Republic of Korea, full, 2015) https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140142
Endocannabinoid signaling in female reproductive events: a potential therapeutic target? (Italy, full, 2015) https://www.tandfonline.com/doi/full/10.1517/14728222.2015.1062878
Gestation Related Gene Expression of the Endocannabinoid Pathway in Rat Placenta. (Australia, full, 2015) https://www.hindawi.com/journals/mi/2015/850471/
A role for GPR55 in human placental venous endothelial cells. (Austria, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487816/
Dynamics of expression and localization of the cannabinoid system in granulosa cells during oocyte nuclear maturation. (Spain, full, 2015) https://www.fertstert.org/article/S0015-0282(15)00440-9/fulltext
Lipopolysaccharide-induced murine embryonic resorption involves changes in endocannabinoid profiling and alters progesterone secretion and inflammatory response by a CB1-mediated fashion. (Argentina/ USA, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458170/
Endocannabinoid signaling at the periphery: 50 years after THC. (Italy/ Israel/ Hungary/ USA/ Qatar/ Canada/ Germany, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420685/
Type 2 cannabinoid receptor contributes to the physiological regulation of spermatogenesis. (Italy, full, 2015) https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.15-279034
Endocannabinoid Regulation of Neuroendocrine Systems. (USA, abstract, 2015) https://www.sciencedirect.com/science/article/pii/S0074774215001282
Anandamide Reduces the Ejaculatory Threshold of Sexually Sluggish Male Rats: Possible Relevance for Human Lifelong Delayed Ejaculation Disorder. (Mexico, abstract, 2015) https://www.semanticscholar.org/paper/Anandamide-reduces-the-ejaculatory-threshold-of-for-Rodr%C3%ADguez-Manzo-Canseco-Alba/3cea7551c8e3a2dc2b6d437527c2e25173a1a730
Anandamide restricts uterine stromal differentiation and is critical for complete decidualization. (Portugal, abstract, 2015) https://www.semanticscholar.org/paper/Anandamide-restricts-uterine-stromal-and-is-for-Fonseca-Correia-da-Silva/aafecbb3581e3671932d45b66f561b4fe544a977
Sperm Release from the Oviductal Epithelium Depends on Ca2+ Influx Upon Activation of CB1 and TRPV1 by Anandamide. (Argentina/ Chile, abstract, 2015) https://www.semanticscholar.org/paper/Sperm-Release-From-the-Oviductal-Epithelium-Depends-Gervasi-Osycka-Salut/844595d299d7569e91195bcf8f8fff0c4ea6afad
Biphasic effects of anandamide on behavioural responses: emphasis on copulatory behaviour. (Mexico, abstract, 2015) https://pubmed.ncbi.nlm.nih.gov/26226145/
Anandamide and Decidual Remodeling: COX-2 oxidative metabolism as a key regulator. (Portugal, abstract, 2015) https://www.sciencedirect.com/science/article/abs/pii/S1388198115001651
2014
PMS, Menses, Menopause and Cannabis (news–2014) http://www.hempista.com/2014/pms-menses-menopause-and-cannabis/
Women find sexual help…with cannabis? (news–2014) http://www.cnbc.com/id/101892786?__source=yahoonews&par=yahoonews#
Estrogen increases cannabis sensitivity (news–2014) http://medicalxpress.com/news/2014-09-estrogen-cannabis-sensitivity.html
Females Build Up Tolerance To Marijuana Faster Than Males, Study Finds (news–2014) http://www.huffingtonpost.com/2014/09/10/females-tolerance-marijua_n_5784022.html