INTERACTIONS WITH OTHER DRUGS

The evidence presented here: 

• 2024
• Drug Interactions in People on Cannabidiol: Is There Cause for Concern?: https://www.liebertpub.com/doi/abs/10.1089/can.2024.0041?utm_source=substack&utm_medium=email
• For cannabinoid drug-drug interactions, a review of 31 reports where cannabinoids produced adverse events or altered drug pharmacokinetics (how they move through the body)
  Systematic review of drug-drug interactions of delta-9-tetrahydrocannabinol, cannabidiol, and Cannabis
  https://pubmed.ncbi.nlm.nih.gov/38868665/
  “Interactions between cannabis/cannabinoids and warfarin, valproate, tacrolimus, and sirolimus were the most widely reported and may pose the greatest risk to patients. Common ADRs included bleeding risk, altered mental status, difficulty inducing anesthesia, and gastrointestinal distress. Additionally, we identified 18 instances (58%) in which clinicians uncovered an unexpected serum level of the prescribed drug.”
• 2023
• Anticoagulant Drug-Drug interactions with cannabinoids: A systematic Review. https://pubmed.ncbi.nlm.nih.gov/37740600/ 
• Final analysis of potential drug-drug interactions between highly purified cannabidiol and anti-seizure medications in an open label, expanded access program. https://pubmed.ncbi.nlm.nih.gov/37593907/ 
• 2021
• Cannabinoid Metabolites as Inhibitors of Major Hepatic CYP450 Enzymes, with Implications for Cannabis-Drug Interactions. https://dmd.aspetjournals.org/content/49/12/1070 
• A Patient’s Guide to CBD and Drug Interactions: Written by Dr. Dustin Sulak: https://healer.com/a-patients-guide-to-cbd-and-drug-interactions/
• IS CBD TOXIC TO THE LIVER?:  https://www.projectcbd.org/science/cbd-toxic-liver?utm_source=Project+CBD+Mailing+List&utm_campaign=fc2e6f0c39-EMAIL_CAMPAIGN_2020_02_26_07_50_COPY_01&utm_medium=email&utm_term=0_ea5031784e-fc2e6f0c39-11562609
• Cannabis-drug interactions are a concern for all patients, but older adults who take multiple medications are at greatest risk:  https://www.crxmag.com/issues/2020/winter/cannabis-drug-interactions.shtml
• Interaction between warfarin and cannabis:  https://www.ncbi.nlm.nih.gov/pubmed/30326170
• Myocardial infarction following the combined recreational use of viagra and cannabis: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6654297/
• 2020
• Oncologists' perspectives on medical marijuana use by older adults. (USA, abstract, 2020) https://www.geriatriconcology.net/article/S1879-4068(19)30413-8/fulltext 
• Medical Cannabis for Intractable Epilepsy in Childhood: A Review. (Israel, full, 2020) https://www.rmmj.org.il/userimages/1024/1/PublishFiles/1029Article.pdf 
• Buprenorphine-cannabis interaction in patients undergoing opioid maintenance therapy. (Germany, full, 2020) https://link.springer.com/article/10.1007%2Fs00406-019-01091-0
• 2019
• Medical Cannabis: Effects on Opioid and Benzodiazepine Requirements for Pain Control. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31129977/ 
• Marijuana Use in the Anesthetized Patient: History, Pharmacology, and Anesthetic Considerations. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31920198/ 
• Cannabis and Turmeric as Complementary Treatments for IBD and Other Digestive Diseases. (USA, abstract, 2019) https://link.springer.com/article/10.1007/s11894-019-0670-0 
• CBD loaded microparticles as a potential formulation to improve paclitaxel and doxorubicin-based chemotherapy in breast cancer. (Spain, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0378517319309615?via%3Dihub 
• A Review of Cannabis and Interactions With Anticoagulant and Antiplatelet Agents. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31724188/ 
• Clinical trial simulations of the interaction between cannabidiol and clobazam and effect on drop-seizure frequency. (Netherlands, abstract, 2019) https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bcp.14158 
• Ligands of the CB2 cannabinoid receptors augment activity of the conventional antidepressant drugs in the behavioural tests in mice. (Poland, abstract, 2019) https://www.sciencedirect.com/science/article/pii/S0166432819311891?via%3Dihub 
• How does cannabidiol (CBD) influence the acute effects of delta-9-tetrahydrocannabinol (THC) in humans? A systematic review. (UK, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0149763419305615?via%3Dihub 
• An assessment of urine THC immunoassay in healthy volunteers receiving an oral proton-pump inhibitor. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31566030/
• Drug–drug interactions and pharmacodynamics of concomitant clobazam and cannabidiol or stiripentol in refractory seizures. (USA, abstract, 2019) https://www.epilepsybehavior.com/article/S1525-5050(19)30449-4/fulltext 
• The Potential for Pharmacokinetic Interactions Between Cannabis Products and Conventional Medications. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31433338/ 
• Distinct inflammatory profiles in HIV-infected individuals under ART using cannabis, cocaine or cannabis plus cocaine. (Brazil, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31490211/ 
• Efficacy of Cannabinoids in a Pre-Clinical Drug-Screening Platform for Alzheimer’s Disease. (USA, abstract, 2019) https://link.springer.com/article/10.1007%2Fs12035-019-1637-8 
• A marijuana-drug interaction primer: Precipitants, pharmacology, and pharmacokinetics. (USA, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0163725819300750 
• Evidence of a clinically significant drug-drug interaction between cannabidiol and tacrolimus. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31012522/ 
• An examination of consequences among college student drinkers on occasions involving alcohol-only, marijuana-only, or combined alcohol and marijuana use. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/30869919/ 
• Perspectives on cannabis as a substitute for opioid analgesics. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/30681029/ 
• Triple comorbid trajectories of alcohol, cigarette, and marijuana use from adolescence to adulthood predict insomnia in adulthood. (USA/ Republic of Korea, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0306460318306385?via%3Dihub 
• Prevalence and Effects of Cigarette Smoking, Cannabis Consumption, and Co-use in Adults From 15 Countries With Congenital Heart Disease. (Belgium/ South Africa/ Canada/ USA/ Switzerland/ Japan/ Netherlands/ Taiwan/ India/ Argentina/ Norway/ Sweden/ Malta/ France/ Australia/ Italy, abstract, 2019) https://www.onlinecjc.ca/article/S0828-282X(19)31150-X/fulltext 
• Δ9-tetrahydrocannabinol attenuates oxycodone self-administration under extended access conditions. (USA, Abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0028390819301212 
• Probable Interaction Between Warfarin and Inhaled and Oral Administration of Cannabis. (USA, PDF, 2019) https://www.researchgate.net/publication/334562028_Probable_Interaction_Between_Warfarin_and_Inhaled_and_Oral_Administration_of_Cannabis 
• Antinociceptive and Abuse Potential Effects of Cannabinoid/Opioid Combinations in a Chronic Pain Model in Rats. (Jordan/ Saudi Arabia, PDF, 2019) https://www.mdpi.com/2076-3425/9/11/328 
• Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use. (USA, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678684/ 
• Effects of Cannabis Use on Sedation Requirements for Endoscopic Procedures. (USA, full, 2019) https://jaoa.org/article.aspx?articleid=2731067 
• Influence of the CB1 and CB2 cannabinoid receptor ligands on the activity of atypical antidepressant drugs in the behavioural tests in mice. (Poland, full, 2019) https://www.sciencedirect.com/science/article/pii/S0091305719304873?via%3Dihub 
• Coadministered cannabidiol and clobazam: Preclinical evidence for both pharmacodynamic and pharmacokinetic interactions. (Australia, full, 2019) https://onlinelibrary.wiley.com/doi/full/10.1111/epi.16355 
• Enhancing Breast Cancer Treatment Using a Combination of Cannabidiol and Gold Nanoparticles for Photodynamic Therapy. (South Africa, full, 2019) https://www.mdpi.com/1422-0067/20/19/4771/htm 
• Joint and separate exposure to alcohol and ∆9-tetrahydrocannabinol produced distinct effects on glucose and insulin homeostasis in male rats. (USA, full, 2019) https://www.nature.com/articles/s41598-019-48466-w 
• A review of the anesthetic implications of marijuana use. (USA, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650211/ 
• Potential Adverse Drug Events and Drug-Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use. (USA, full, 2019) https://www.mdpi.com/2077-0383/8/7/989/htm 
• Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration. (USA, full, 2019) https://www.mdpi.com/1420-3049/24/12/2256/htm 
• Medical Marijuana: What Physicians Need to Know. (USA, full, 2019) https://www.psychiatrist.com/JCP/article/Pages/medical-marijuana-what-physicians-need-to-know.aspx 
• ∆9-Tetrahydrocannabinol, a major marijuana component, enhances the anesthetic effect of pentobarbital through the CB1 receptor. (Japan, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314990/ 
• Study: THC Enhances Analgesic Effects Of Opioids In Animal Model. (news – 2019)
  https://norml.org/news/2019/05/16/study-thc-enhances-analgesic-effects-of-opioids-in-animal-model
• If you smoke pot, your anesthesiologist needs to know. (news – 2019)
  https://www.nbcnews.com/health/health-news/if-you-smoke-pot-your-anesthesiologist-needs-know-n1038191
• CBDs Help Medication Cross the Blood Brain Barrier. (news – 2019)
  https://www.labroots.com/trending/cannabis-sciences/14554/cbds-help-medication-cross-blood-brain-barrier
• 2018
• Combined ∆9-tetrahydrocannabinol and moderate alcohol administration: effects on ingestive behaviors in adolescent male rats. (USA, abstract, 2018) https://link.springer.com/article/10.1007%2Fs00213-018-5093-3 
• The Relationship Between Tobacco and Cannabis Use: A Review. (Canada, abstract, 2018) https://pubmed.ncbi.nlm.nih.gov/30362881/ 
• THC and gabapentin interactions in a mouse neuropathic pain model. (Australia, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0028390818307779?via%3Dihub 
• Effects of Δ9-tetrahydrocannabinol on irinotecan-induced clinical effects in rats. (Croatia, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0009279718308792?via%3Dihub 
• Optimization Of A Preclinical Therapy Of Cannabinoids In Combination With Temozolomide Against Glioma. (Spain, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0006295218303496 
• Synthetic cannabinoids are substrates and inhibitors of multiple drug-metabolizing enzymes. (Republic of Korea, abstract, 2018) https://link.springer.com/article/10.1007/s12272-018-1055-x 
• EFFECTS OF CANNABIS EXTRACT PREMEDICATION ON ANESTHETIC DEPTH. (Israel, abstract, 2018) https://pubmed.ncbi.nlm.nih.gov/29582946/ 
• Pseudo-Wellens' syndrome secondary to concurrent cannabis and phencyclidine (PCP) intoxication. (USA/ Pakistan, abstract, 2018) https://casereports.bmj.com/content/2018/bcr-2018-225755 
• CB1 cannabinoid receptor ligands augment the antidepressant-like activity of biometals (magnesium and zinc) in the behavioural tests. (Poland, abstract, 2018) https://pubmed.ncbi.nlm.nih.gov/29380383/ 
• Cannabis Use and Bleomycin: An Overview and Case Study of Pulmonary Toxicity. (USA, abstract, 2018) https://www.semanticscholar.org/paper/Cannabis-Use-and-Bleomycin%3A-An-overview-and-case-of-Merkle-Tavernier/0204a281f8fe5a4dd5bd26fe094010da67cec691 
• Safety of cannabidiol prescribed for children with refractory epilepsy. (Italy, letter, 2018) https://www.mja.com.au/journal/2018/209/5/safety-cannabidiol-prescribed-children-refractory-epilepsy 
• Cannabis and Anti-Cancer Drugs: Societal Usage and Expected Pharmacological Interactions - A Review. (France, PDF, 2018) https://www.ch-thuir.fr/sites/default/files/Bouqui-_et_al-2018-Fundamental_&_Clinical_Pharmacology.pdf 
• Practical considerations in medical cannabis administration and dosing. (Canada/ Czech Republic, PDF, 2018) https://www.researchgate.net/publication/322257368_Practical_considerations_in_medical_cannabis_administration_and_dosing 
• Medicinal Cannabis—Potential Drug Interactions. (Australia/ Egypt, full, 2018) https://www.mdpi.com/2305-6320/6/1/3/htm 
• Targeting Glioma Initiating Cells With A Combined Therapy Of Cannabinoids And Temozolomide. (Spain, full, 2018) https://www.sciencedirect.com/science/article/pii/S0006295218303897 
• Differential associations of combined vs. isolated cannabis and nicotine on brain resting state networks. (USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286234/ 
• Effect of adding medical cannabis to analgesic treatment in patients with low back pain related to fibromyalgia: an observational cross-over single centre study. (Israel, full, 2018) https://anaesthesia-painmedicine.imedpub.com/effect-of-adding-medical-cannabis-treatment-mct-to-analgesic-treatment-in-patients-with-low-back-pain-related-to-fibromyalgia-an-o.php?aid=20234 
• Impact of co-administration of oxycodone and smoked cannabis on analgesia and abuse liability. (USA/ Australia, full, 2018) https://www.nature.com/articles/s41386-018-0011-2 
• Risperidone Provides Better Improvement of Sleep Disturbances Than Haloperidol Therapy in Schizophrenia Patients With Cannabis-Positive Urinalysis. (Jamaica, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058192/ 
• Efficacy of cannabinoids in paediatric epilepsy. (New Zealand/ Australia, full, 2018) https://onlinelibrary.wiley.com/doi/full/10.1111/dmcn.14087 
• Cannabidiol enhances morphine antinociception, diminishes NMDA-mediated seizures and reduces stroke damage via the sigma 1 receptor. (Spain, full, 2018) https://molecularbrain.biomedcentral.com/articles/10.1186/s13041-018-0395-2 
• Cannabidiol (CBD) Is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer. (UK, full, 2018) https://www.frontiersin.org/articles/10.3389/fphar.2018.00889/full 
• Irinotecan and Δ⁸-Tetrahydrocannabinol Interactions in Rat Liver: A Preliminary Evaluation Using Biochemical and Genotoxicity Markers. (Croatia, full, 2018) https://www.mdpi.com/1420-3049/23/6/1332/htm 
• Intrathecal morphine administration reduces postoperative pain and peripheral endocannabinoid levels in total knee arthroplasty patients: a randomized clinical trial. (USA, full, 2018) https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-018-0489-5 
• An interaction between warfarin and cannabidiol, a case report. (USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789126/ 
• Cannabis and the Opioid Crisis. (interview – 2018)
  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931647/
• Relationship Between Marijuana and Opioids. (news – 2018)
  https://norml.org/marijuana/fact-sheets/item/relationship-between-marijuana-and-opioids
• Coffee Cannabis Connection. (news – 2018)
  https://neurosciencenews.com/coffee-cannabis-system-8649/
• Could Chamomile and Cannabis Oil Kill Cancer Cells? (news – 2018)
  https://unitedpatientsgroup.com/blog/2018/05/08/chamomile-and-cannabis-oil-for-cancer/
• 2017
• Δ9-tetrahydrocannabinol (Δ9-THC) administration after neonatal exposure to phencyclidine (PCP) potentiates schizophrenia-related behavioral phenotypes in mice. (USA, abstract, 2017) https://www.sciencedirect.com/science/article/abs/pii/S0091305717301211 
• Interactive effects of morphine and nicotine on memory function depend on the central amygdala cannabinoid CB1 receptor function in rats. (Iran, abstract, 2017) https://www.sciencedirect.com/science/article/abs/pii/S0278584617304554?via%3Dihub 
• Concurrent use of cannabis and alcohol: neuropsychiatric effects and consequences. (Spain, abstract, 2017) https://pubmed.ncbi.nlm.nih.gov/28440194/ 
• Contribution of CB1Rs in anxiety-related behaviors but not locomotor deficits induced by methamphetamine. (Iran, PDF, 2017) https://www.researchgate.net/publication/321739457_Contribution_of_CB1Rs_in_anxiety-related_behaviors_but_not_locomotor_deficits_induced_by_methamphetamine 
• Are cannabinoids effective for the management of chemotherapy induced nausea and vomiting? (Chile, PDF, 2017) https://www.medwave.cl/link.cgi/English/Updates/Epistemonikos/7120 
• Drug-drug interactions as a result of co-administering Δ9-THC and CBD with other psychotropic agents. (Canada/ Netherlands/ Singapore, full, 2017) https://www.grecc.org/publications/essais-cliniques/drug-drug-interactions-as-a-result-of-coadministering-%CE%B49-thc-and-cbd-with-other-psychotropic-agents-carola-rong-et-al-2018/ 
• The Impact of Combinations of Alcohol, Nicotine, and Cannabis on Dynamic Brain Connectivity. (USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809800/ 
• Opioid-sparing Effect of Cannabinoids: A Systematic Review and Meta-analysis. (Australia/ Canada, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520783/ 
• The Differential Binding of Antipsychotic Drugs to the ABC Transporter P-Glycoprotein Predicts Cannabinoid-Antipsychotic Drug Interactions. (Australia, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603813/ 
• Pharmacological and Toxicological Effects of Synthetic Cannabinoids and Their Metabolites. (USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392241/ 
• Cross-Reactivity of Pantoprazole with Three Commercial Cannabinoids Immunoassays in Urine. (Spain, full, 2017) https://academic.oup.com/jat/article/41/9/760/3958769 
• Synergistic interaction of the cannabinoid and death receptor systems: A potential target for future cancer therapies? (USA, full, 2017) https://febs.onlinelibrary.wiley.com/doi/full/10.1002/1873-3468.12863 
• Acute memory and psychotomimetic effects of cannabis and tobacco both ‘joint’ and individually: a placebo-controlled trial. (UK/ USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647681/ 
• Medicinal Cannabis: History, Pharmacology, And Implications for the Acute Care Setting. (USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569602/ 
• Chili peppers, marijuana may reduce gut inflammation (news–2017) http://www.medicalnewstoday.com/articles/317128.php
• Should You Mix Turmeric And Weed For Pain Management? (news–2017) http://www.thealternativedaily.com/turmeric-and-weed-for-pain/
• Cannabinoids and chemotherapy in combination kill cancer cells (news–2017) http://www.medicalnewstoday.com/articles/317798.php
• Stirring the Pot: Potential Drug Interactions With Marijuana (news–2017) http://www.medscape.com/viewarticle/881059
• Not Telling Your Doctor About Marijuana Use Can Hurt You (news–2017) https://thefreshtoast.com/cannabis/what-you-dont-tell-your-doctor-about-using-marijuana-can-hurt-you/
• 2016
• Preliminary Results of Uab’s Cbd Oil Studies Show Promise (news–2016) http://www.newswise.com/articles/view/649217/?sc=rsmn
• Coffee Pot: What Happens When You Mix Marijuana & Caffeine? (news–2016) https://www.yahoo.com/news/coffee-pot-happens-mix-marijuana-caffeine-161611734.html?ref=gs
• Combination of marijuana and tobacco in pregnancy may compound risks (news–2016) http://www.reuters.com/article/us-health-pregnancy-marijuana-tobacco-idUSKCN0YV2BN
• Ebbu Announces Groundbreaking Scientific Research of “Entourage Effect” (news–2016) http://www.businesswire.com/news/home/20160623005867/en/
• Mixing pot and tobacco increases dependence risk (news–2016) http://www.upi.com/Health_News/2016/07/06/Mixing-pot-and-tobacco-increases-dependencerisk/8041467788885/
• Does medical marijuana reduce need for other meds? (news–2016) http://www.webmd.com/news/20160706/does-medical-marijuana-reduce-need-for-other-meds
• Spliffs Are Poison, Destroy Lungs (news–2016) https://www.greenrushdaily.com/2016/01/12/spliffs-poison-destroy-lungs/
• Marijuana Use by Older Adults (news–2016) http://learnaboutmarijuanawa.org/factsheets/olderadults.htm
• Mixing the Pot? 7 Ways Marijuana Interacts with Medicines (news–2016) https://www.livescience.com/56439-how-marijuana-interacts-with-medicines.html
• 2015
• Veterans Health Administration Policy on Cannabis as an Adjunct to Pain Treatment with Opiates (article–2015) http://journalofethics.ama-assn.org/2015/06/pfor2-1506.html
• Nicotine Changes Marijuana’s Effect on the Brain (news & abstract-2015) http://neurosciencenews.com/hippocampal-volume-nicotine-marijuana-2457/
• Substance abuse risk not greater in those using medical marijuana with prescribed opioids (news–2015) http://www.eurekalert.org/pub_releases/2015-05/joso-sar051115.php
• 2014
• Hormone shows promise at negating marijuana’s high effect (news–2014) http://www.cbsnews.com/news/hormone-shows-promise-at-negating-marijuanas-high-effect/
• Active ingredient in pot sets off a feedback that reduces intoxication (news–2014) http://arstechnica.com/science/2014/01/active-ingredient-in-pot-sets-off-a-feedback-that-reduces-intoxication/
• Muting Marijuana’s High: Pot Without the Impairment (news–2014) http://healthland.time.com/2014/01/03/muting-marijuanas-high-pot-without-the-impairment/
• Alcohol and drugs put teens at increased risk for unsafe driving (news–2014) http://www.news-medical.net/news/20140428/Alcohol-and-drugs-put-teens-at-increased-risk-for-unsafe-driving.aspx
• Medical marijuana laws may reduce painkiller overdoses (news–2014) http://www.cnn.com/2014/08/25/health/medical-marijuana-overdose-deaths/index.html
• How Black Pepper relieves Cannabis Anxiety (news–2014) http://cannabisdigest.ca/black-pepper-relieves-cannabis-anxiety/
• Why growing numbers of pot smokers eat mango before lighting up (news–2014) http://www.salon.com/2014/07/11/why_growing_numbers_of_pot_smokers_eat_mango_before_lighting_up_partner/
• Study: THC Reduces Methamphetamine-Induced Brain Damage (news–2014) https://www.theweedblog.com/study-thc-reduces-methamphetamine-induced-brain-damage/
• 2011
• Marijuana, Narcotics Help Patients Reduce Chronic Pain, Study Finds (news–2011) http://www.huffingtonpost.com/2011/12/08/marijuana-narcotics-help-patients-reduce-pain_n_1137416.html