MULTIPLE SCLEROSIS (MS) – Leaf411

MULTIPLE SCLEROSIS (MS):

2022:
The cannabinoids and terpenes with anti-inflammatory potential: https://cannabishealthnews.co.uk/2022/11/22/cannabinoids-and-terpenes-anti-inflammatory-potential/
2021:
Can Medical Marijuana Help Your MS? (news – 2015)
https://www.webmd.com/multiple-sclerosis/multiple-sclerosis-medical-marijuana?src=RSS_PUBLIC#1
(THC) and cannabidiol (CBD) oromucosal spray in resistant multiple sclerosis spasticity-consistency of response across subgroups from the SAVANT randomized clinical trial: https://www.tandfonline.com/doi/abs/10.1080/00207454.2020.1730832
2020
Dose-dependent effect of cannabinoid WIN-55,212-2 on myelin repair following a demyelinating insult. (Germany/ Spain/ Ghana, full, 2020) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969154/
2019
An Update of Current Cannabis-Based Pharmaceuticals in Pain Medicine. (USA, full, 2019) https://link.springer.com/article/10.1007%2Fs40122-019-0114-4
Marijuana Use by Patients with Multiple Sclerosis. (USA, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489434/
Combination of Cannabinoids, Δ9- Tetrahydrocannabinol and Cannabidiol, Ameliorates Experimental Multiple Sclerosis by Suppressing Neuroinflammation Through Regulation of miRNA-Mediated Signaling Pathways. (USA, full, 2019) https://www.frontiersin.org/articles/10.3389/fimmu.2019.01921/full
The endocannabinoid 2-AG enhances spontaneous remyelination by targeting microglia. (Spain/ Canada, full, 2019) https://www.sciencedirect.com/science/article/pii/S0889159118302411?via%3Dihub
Activity-Based Protein Profiling Delivers Selective Drug Candidate ABX-1431, a Monoacylglycerol Lipase Inhibitor, To Control Lipid Metabolism in Neurological Disorders. (Netherlands, full, 2019) https://pubs.acs.org/doi/10.1021/acs.jmedchem.8b01405
Cannabis-based product use in a multiple sclerosis cohort. (Canada, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764052/
Cannabinoids for the treatment of spasticity. (Australia, abstract in English, links to Portuguese & Spanish, 2019) https://pubmed.ncbi.nlm.nih.gov/30680713/
Illegal cannabis use is common among Danes with multiple sclerosis. (Denmark, abstract, 2019) https://www.msard-journal.com/article/S2211-0348(19)30212-3/fulltext
Caring for people with multiple sclerosis who use cannabis for symptom control. (UK, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31166770/
Combination of cannabinoids, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), mitigates experimental autoimmune encephalomyelitis (EAE) by altering the gut microbiome. (USA, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0889159119306476?via%3Dihub
Cannabinoid CB2 Receptor Functional Variation (Q63R) Is Associated with Multiple Sclerosis in Iranian Subjects. (Iran, abstract, 2019) https://www.semanticscholar.org/paper/Cannabinoid-CB2-Receptor-Functional-Variation-Is-in-Tahamtan-Rezaiy/0bd38a0c052e06c8ef7f40cfd5a89a009f8cd7b3
Exploring cannabis use by patients with multiple sclerosis in a state where cannabis is legal. (USA, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S2211034818305157
Combination of Imipramine, a sphingomyelinase inhibitor, and β-caryophyllene improve their therapeutic effects on experimental autoimmune encephalomyelitis (EAE). (Iran, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31711937/
Safety, efficacy, and mechanisms of action of cannabinoids in neurological disorders. (USA/ Italy, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S1474442219300328
Dronabinol use in France between 2004 and 2017. (France, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0035378717308019
Pain Management in Multiple Sclerosis: a Review of Available Treatment Options. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31773455/
Cannabinoids and the expanded endocannabinoid system in neurological disorders. (Italy/ Canada, abstract, 2019) https://www.nature.com/articles/s41582-019-0284-z
The Effects of Chronic Δ-9-Tetrahydrocannabinol (THC) and Cannabidiol (CBD) use on Cerebral Glucose Metabolism in Multiple Sclerosis: A Pilot Study. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31841355/
Cannabis Use for Symptom Relief in Multiple Sclerosis: A Cross-Sectional Survey of Webinar Attendees in the US and Canada. (USA, abstract, 2019) https://www.msard-journal.com/article/S2211-0348(19)30837-5/fulltext
2018
Researchers Say Cannabis Can Benefit People with Multiple Sclerosis. (news – 2018)
https://www.healthline.com/health-news/researchers-say-cannabis-can-benefit-people-with-multiple-sclerosis#1
Cannabidiol to Improve Mobility in People with Multiple Sclerosis. (USA, full, 2018) https://www.frontiersin.org/articles/10.3389/fneur.2018.00183/full#B19
The influence of THC:CBD oromucosal spray on driving ability in patients with multiple sclerosis‐related spasticity. (Norway/ Spain, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943754/
Pain Modulation after Oromucosal Cannabinoid Spray (SATIVEX®) in Patients with Multiple Sclerosis: A Study with Quantitative Sensory Testing and Laser-Evoked Potentials. (Italy, full, 2018) https://www.mdpi.com/2305-6320/5/3/59/htm
Therapeutic potential of medicinal marijuana: an educational primer for health care professionals. (Canada, full, 2018) https://www.dovepress.com/therapeutic-potential-of-medicinal-marijuana-an-educational-primer-for-peer-reviewed-fulltext-article-DHPS
Ajulemic acid: potential treatment for chronic inflammation. (USA, full, 2018) https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1002/prp2.394
The Management of Lower Urinary Tract Dysfunction in Multiple Sclerosis. (UK, full, 2018) https://link.springer.com/article/10.1007%2Fs11910-018-0857-z
Hypoxia mimetic activity of VCE-004.8, a cannabidiol quinone derivative: implications for multiple sclerosis therapy. (Spain/ USA/ Italy/ Germany, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831753/
Delta-9-tetrahydrocannabinol and cannabidiol: Separating the chemicals from the "weed," a pharmacodynamic discussion. (USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007535/
An Inflammation-Centric View of Neurological Disease: Beyond the Neuron. (Italy, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871676/
Cannabidiol Attenuates Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis Through Induction of Myeloid-Derived Suppressor Cells. (USA, full, 2018) https://www.frontiersin.org/articles/10.3389/fimmu.2018.01782/full
Traditional Uses of Cannabinoids and New Perspectives in the Treatment of Multiple Sclerosis. (Italy, full, 2018) https://www.mdpi.com/2305-6320/5/3/91/htm
Multiple Sclerosis, Cannabis Use, and Clinical Disability: A Preliminary [18F]- Fluorodeoxyglucose Positron Emission Tomography Study. (USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186162/
Cannabis Therapeutics and the Future of Neurology. (USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200872/
Medical cannabis in the treatment of cancer pain and spastic conditions and options of drug delivery in clinical practice. (Czech Republic, link to PDF, 2018) http://biomed.papers.upol.cz/artkey/bio-201801-0003_medical_cannabis_in_the_treatment_of_cancer_pain_and_spastic_conditions_and_options_of_drug_delivery_in_clinica.php
Tetrahydrocannabinol/Cannabidiol Oromucosal Spray in Patients With Multiple Sclerosis: A Pilot Study on the Plasma Concentration-Effect Relationship. (Italy, link to PDF, 2018) https://www.researchgate.net/publication/326496634_TetrahydrocannabinolCannabidiol_Oromucosal_Spray_in_Patients_With_Multiple_Sclerosis_A_Pilot_Study_on_the_Plasma_Concentration-Effect_Relationship
Practical considerations in medical cannabis administration and dosing. (Canada/ Czech Republic, link to PDF, 2018) https://www.researchgate.net/publication/322257368_Practical_considerations_in_medical_cannabis_administration_and_dosing
The Use of Cannabis and Cannabinoids in Treating Symptoms of Multiple Sclerosis: a Systematic Review of Reviews. (Australia, abstract, 2018) https://link.springer.com/article/10.1007/s11910-018-0814-x
Innovative Therapeutic Potential of Cannabinoid Receptors as Targets in Alzheimer's disease and Less Well-Known Diseases. (Spain, Abstract, 2018) https://www.ingentaconnect.com/content/ben/cmc/2019/00000026/00000018/art00009
The therapeutic effects of Cannabis and cannabinoids: An update from the National Academies of Sciences, Engineering and Medicine report. (USA, Abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0953620518300037
Cannabinoid therapy in practice. (Germany, abstract in German & English, 2018) https://link.springer.com/article/10.1007%2Fs00120-018-0636-0
The inhibition of CB1 receptor accelerates the onset and development of EAE possibly by regulating microglia/macrophages polarization. (China, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0165572817304678
Evaluation of Marijuana Compounds on Neuroimmune Endpoints in Experimental Autoimmune Encephalomyelitis. (USA, abstract, 2018) https://pubmed.ncbi.nlm.nih.gov/29512125/
Clinical response to Nabiximols correlates with the down-regulation of immune pathways in Multiple Sclerosis. (Italy, abstract, 2018) https://www.semanticscholar.org/paper/Clinical-response-to-Nabiximols-correlates-with-the-Sorosina-Clarelli/47d74742e4fbfc8afe7be648f8d72f9e79853987
Cannabinoids for Treatment of MS Symptoms: State of the Evidence. (USA, abstract, 2018) https://link.springer.com/article/10.1007%2Fs11910-018-0859-x
Deregulation of the endocannabinoid system and therapeutic potential of ABHD6 blockade in the cuprizone model of demyelination. (Spain/ USA, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0006295218303113
Gut microbiota, cannabinoid system and neuroimmune interactions: New perspectives in multiple sclerosis. (Spain, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0006295218303630
Avidekel Cannabis extracts and cannabidiol are as efficient as Copaxone in suppressing EAE in SJL/J mice. (Israel, abstract, 2018) https://link.springer.com/article/10.1007/s10787-018-0536-3
β-Amyrin, the cannabinoid receptors agonist, abrogates mice brain microglial cells inflammation induced by lipopolysaccharide/interferon-γ and regulates Mφ1/Mφ2 balances. (Iran, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0753332217358201?via%3Dihub
2017
Massive scientific report on marijuana confirms medical benefits (news–2017) http://arstechnica.com/science/2017/01/massive-scientific-report-on-marijuana-confirms-medical-benefits/
5 Positive Takeaways From The Groundbreaking Health Report On Cannabis (news–2017) https://www.civilized.life/articles/the-latest-cannabis-health-report/
Retired rabbi turned medical marijuana dispensary owner says Ohio laws will change: Q&A (news–2017) http://www.cleveland.com/metro/index.ssf/2017/03/thoughts_on_ohios_medical_mari.html
Marijuana ‘saved my life’ (news–2017) http://www.wollondillyadvertiser.com.au/story/4678497/marijuana-saved-my-life/
Cannabinoids May Treat Oxidative Stress-Related Neurodegenerative Disorders, Says New Study (news–2017) https://thejointblog.com/cannabinoids-may-treat-oxidative-stress-related-neurodegenerative-disorders-says-new-study/
Does the Gut Microbiota Influence Immunity and Inflammation in Multiple Sclerosis Pathophysiology? (Poland, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337874/
Cannabis and cognitive functioning in multiple sclerosis: The role of gender. (Canada, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468765/
Cannabis and Multiple Sclerosis—The Way Forward. (USA, full, 2017) https://www.frontiersin.org/articles/10.3389/fneur.2017.00299/full
Understanding Patients' Process to Use Medical Marijuana: A Southern New Jersey Community Engagement Project. (USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513646/
Modulation of Astrocyte Activity by Cannabidiol, a Nonpsychoactive Cannabinoid. (Israel, full, 2017) https://www.mdpi.com/1422-0067/18/8/1669/htm
Cannabis-induced alterations in brain activation during a test of information processing speed in patients with MS. (Canada, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433500/
(-)-β-Caryophyllene, a CB2 Receptor-Selective Phytocannabinoid, Suppresses Motor Paralysis and Neuroinflammation in a Murine Model of Multiple Sclerosis. (Brazil, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412277/
The endocannabinoid system and its therapeutic exploitation in multiple sclerosis: Clues for other neuroinflammatory diseases. (Italy, full, 2017) https://www.sciencedirect.com/science/article/pii/S0301008217300709?via%3Dihub
Oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunomodulation. (UK/ Iraq, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674070/
Immunoregulatory Role of Cannabinoids during Infectious Disease. (Mexico, full, 2017) https://www.karger.com/Article/FullText/481824
Chapter 4 Neuropathic Pain in Multiple Sclerosis—Current Therapeutic Intervention and Future Treatment Perspectives. (USA, full, 2017) https://www.ncbi.nlm.nih.gov/books/NBK470151/
The role of Sativex in robotic rehabilitation in individuals with multiple sclerosis: Rationale, study design, and methodology. (Italy, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704890/
2-arachidonoylglycerol reduces proteoglycans and enhances remyelination in a progressive model of demyelination. (Spain/ Canada, full, 2017) https://www.jneurosci.org/content/37/35/8385.long
Cannabinoids for treating neurogenic lower urinary tract dysfunction in patients with multiple sclerosis: a systematic review and meta-analysis. (Switzerland/ France/ UK, full, 2017) https://bjui-journals.onlinelibrary.wiley.com/doi/full/10.1111/bju.13759
Effects on Spasticity and Neuropathic Pain of an Oral Formulation of Δ9- Tetrahydrocannabinol in Patients With Progressive Multiple Sclerosis. (Netherlands, full, 2017) https://www.clinicaltherapeutics.com/article/S0149-2918(17)30054-1/fulltext?rss=yes
Perspectives on marijuana use and effectiveness: A survey of NARCOMS participants. (USA/ Canada, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648201/
Neuroprotection in oxidative stress-related neurodegenerative diseases: role of endocannabinoid system modulation. (USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984569/
Cannabis use in people with Parkinson's disease and Multiple Sclerosis: A web-based investigation. (USA, link to PDF, 2017) https://www.researchgate.net/publication/318332922_Cannabis_use_in_people_with_Parkinson%27s_disease_and_Multiple_Sclerosis_A_web-based_investigation
Efficacy, tolerability and safety of cannabis-based medicines for chronic pain management - An overview of systematic reviews. (Germany/ Canada, abstract, 2017) https://onlinelibrary.wiley.com/doi/abs/10.1002/ejp.1118
Systematic review of safeness and therapeutic efficacy of cannabis in patients with multiple sclerosis, neuropathic pain, and in oncological patients treated with chemotherapy. (Italy, abstract, 2017) http://www.epiprev.it/articolo_scientifico/revisione-sistematica-sull%E2%80%99efficacia-terapeutica-e-la-sicurezza-della-cannabis-
At the intersection of neurology and psychiatry : the impact of the differential diagnosis. (France, abstract, 2017) https://pubmed.ncbi.nlm.nih.gov/28653514/
Cannabinoids therapeutic use: what is our current understanding following the introduction of THC, THC:CBD oromucosal spray and others? (Italy/ Spain/ Germany, abstract, 2017) https://pubmed.ncbi.nlm.nih.gov/28276775/
TRPV1 polymorphisms and risk of interferon β-induced flu-like syndrome in patients with relapsing-remitting multiple sclerosis. (Italy, abstract, 2017) https://www.jni-journal.com/article/S0165-5728(16)30424-6/fulltext
The impact of cannabis and cannabinoids for medical conditions on health-related quality of life: A systematic review and meta-analysis. (USA, abstract, 2017) https://www.sciencedirect.com/science/article/abs/pii/S0376871617300881
The effect of symptom-controlling medication on gait outcomes in people with multiple sclerosis: a systematic review. (Australia, abstract, 2017) https://www.semanticscholar.org/paper/The-effect-of-symptom-controlling-medication-on-in-Behm-Morgan/8b60e72bcf4aa94c3ea9e2540739b6f9fa54b134
Perspectives of Cannabinoid type 2 receptor (CB2R) ligands in neurodegenerative disorders: Structure Affinity Relationship (SAfiR) and Structure Activity Relationship (SAR) Studies. (Italy/ Albania, abstract, 2017) https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.7b00155
Sativex® effects on promoter methylation and on CNR1/CNR2 expression in peripheral blood mononuclear cells of progressive multiple sclerosis patients. (Italy, abstract, 2017) https://www.sciencedirect.com/science/article/abs/pii/S0022510X17303921
Interferon-γ causes mood abnormalities by altering cannabinoid CB1 receptor function in the mouse striatum. (Italy, abstract, 2017) https://www.sciencedirect.com/science/article/abs/pii/S0969996117301717?via%3Dihub
Managing neuropathic pain in multiple sclerosis: Pharmacological interventions. (Australia, abstract, 2017) https://www.eurekaselect.com/155364/article
Cannabinoids for spasticity due to multiple sclerosis or paraplegia: A systematic review and meta-analysis of randomized clinical trials. (Brazil/ Canada, abstract, 2017) https://www.sciencedirect.com/science/article/abs/pii/S0965229917304466
THC/CBD oromucosal spray in patients with multiple sclerosis overactive bladder: a pilot prospective study. (Italy, abstract, 2017) https://link.springer.com/article/10.1007/s10072-017-3148-6
Preserving the independence of people living with multiple sclerosis towards the end of life. (UK, abstract, 2017) https://pubmed.ncbi.nlm.nih.gov/29087751/
Attitudes, perceptions, and use of marijuana in youth with multiple sclerosis. (USA, abstract, 2017) https://www.semanticscholar.org/paper/Attitudes%2C-perceptions%2C-and-use-of-marijuana-in-Brenton-Schreiner/44f4e1a9aadbff2353a056da7996a51edc376320
2016
Evidence for the efficacy and effectiveness of THC-CBD oromucosal spray in symptom management of patients with spasticity due to multiple sclerosis. (Germany, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710104/
Systematic Review of Pharmacological Properties of the Oligodendrocyte Lineage. (Italy, full, 2016) https://www.frontiersin.org/articles/10.3389/fncel.2016.00027/full
THC:CBD Observational Study Data: Evolution of Resistant MS Spasticity and Associated Symptoms. (Italy, full, 2016) https://www.karger.com/Article/FullText/444235
THC:CBD in Daily Practice: Available Data from UK, Germany and Spain. (Spain, full, 2016) https://www.karger.com/Article/FullText/444234
Pathways and gene networks mediating the regulatory effects of cannabidiol, a nonpsychoactive cannabinoid, in autoimmune T cells. (Israel/ USA, full, 2016) https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-016-0603-x
Efficacy and safety of cannabinoid oromucosal spray for multiple sclerosis spasticity. (Italy, full, 2016) https://jnnp.bmj.com/content/87/9/944.long
Interaction between interleukin-1β and type-1 cannabinoid receptor is involved in anxiety-like behavior in experimental autoimmune encephalomyelitis. (Italy/ Germany, full, 2016) https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-016-0682-8
Potential Future Pharmacological Treatment of Bladder Dysfunction. (USA/ Denmark, full, 2016) https://onlinelibrary.wiley.com/doi/full/10.1111/bcpt.12577
Evaluating Sativex® in Neuropathic Pain Management: A Clinical and Neurophysiological Assessment in Multiple Sclerosis. (Italy, full, 2016) https://academic.oup.com/painmedicine/article/17/6/1145/1752844
Chromenopyrazole, a Versatile Cannabinoid Scaffold with in Vivo Activity in a Model of Multiple Sclerosis. (Spain/ USA, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321205/
Development and Pharmacological Characterization of Selective Blockers of 2- Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain. (Italy/ France/ USA, full, 2016) https://escholarship.org/uc/item/0nc4z28r
Cannabinoids and Neuro-Inflammation: Regulation of Brain Immune Response. (Italy, link to PDF, 2016) https://www.researchgate.net/publication/304361367_Cannabinoids_and_Neuro-Inflammation_Regulation_of_Brain_Immune_Response
The effect of cannabinoids on the stretch reflex in multiple sclerosis spasticity. (Italy, link to download, 2016) https://www.semanticscholar.org/paper/The-effect-of-cannabinoids-on-the-stretch-reflex-in-Marinelli-Mori/5ac2d9162b74ff0c71df60ff4fffdc45b006f522?p2df
Cannabinoids and autoimmune diseases: A systematic review. (Israel, click “cedfoundation” for download, 2016) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Cannabinoids+and+autoimmune+diseases%3A+A+systematic+review.%22&btnG
Target regulation of PI3K/Akt/mTOR pathway by cannabidiol in treatment of experimental multiple sclerosis. (Italy, Abstract, 2016) https://www.sciencedirect.com/science/article/abs/pii/S0367326X16304476
Role of nurses in the managements of symptoms associated with spasticity in patients with multiple sclerosis. (Spain, abstract in English & Spanish, 2016) https://www.elsevier.es/es-revista-enfermeria-clinica-35-articulo-manejo-los-sintomas-asociados-espasticidad-S1130862116300882
Medical use of cannabis products : Lessons to be learned from Israel and Canada. (Germany, abstract in English & German, 2016) https://link.springer.com/article/10.1007/s00482-015-0083-4
A cost-effectiveness model for the use of a cannabis-derived oromucosal spray for the treatment of spasticity in multiple sclerosis. (UK, abstract, 2016) https://pubmed.ncbi.nlm.nih.gov/26750641/
The emerging role of the cannabinoid receptor family in peripheral and neuro-immune interactions. (Ireland, abstract, 2016) https://www.eurekaselect.com/138448/article
Cannabinoids: Medical implications. (USA, abstract, 2016) https://www.semanticscholar.org/paper/Cannabinoids%3A-Medical-implications-Schrot-Hubbard/2aab2c83e7a45a160550cdad7a2c877e02b2c9cc
Toll-like receptor signalling as a cannabinoid target in Multiple Sclerosis. (Ireland, abstract, 2016) https://www.sciencedirect.com/science/article/abs/pii/S0028390816301459
MEDICAL CANNABIS. (Israel, abstract, 2016) https://pubmed.ncbi.nlm.nih.gov/27215115/
Influence of Previous Failed Antispasticity Therapy on the Efficacy and Tolerability of THC:CBD Oromucosal Spray for Multiple Sclerosis Spasticity. (Germany, abstract, 2016) https://pubmed.ncbi.nlm.nih.gov/27160412/
Refractory trigeminal neuralgia responsive to nabiximols in a patient with multiple sclerosis. (Italy, abstract, 2016) https://www.msard-journal.com/article/S2211-0348(16)30056-6/abstract
Modulation of monocytes by bioactive lipid anandamide in multiple sclerosis involves distinct Toll-like receptors. (Italy/ UK, abstract, 2016) https://www.sciencedirect.com/science/article/abs/pii/S1043661816309021
Cortical and spinal excitability in patients with multiple sclerosis and spasticity after oromucosal cannabinoid spray. (Italy, abstract, 2016) https://www.jns-journal.com/article/S0022-510X(16)30620-7/fulltext
Medical Cannabis - another piece in the mosaic of autoimmunity? (Israel, abstract, 2016) https://pubmed.ncbi.nlm.nih.gov/27859024/
Muscle elastography: a new imaging technique for multiple sclerosis spasticity measurement. (Italy, abstract, 2016) https://www.semanticscholar.org/paper/Muscle-elastography%3A-a-new-imaging-technique-for-Illomei-Spinicci/3caaf974bc120139c13f0c96b53db7f548285777
Attitudes to cannabis and patterns of use among Canadians with multiple sclerosis. (Canada, abstract, 2016) https://www.semanticscholar.org/paper/Attitudes-to-cannabis-and-patterns-of-use-among-Banwell-Pavisian/d6b1312f0d1dca1ed8eef6859683fb35e9145d41
Potent immunomodulatory activity of a highly selective cannabinoid CB2 agonist on immune cells from healthy subjects and patients with multiple sclerosis. (Italy, abstract, 2016) https://www.jni-journal.com/article/S0165-5728(16)30274-0/fulltext#relatedArticles
2015
The entourage effect: Synergistic actions of plant cannabinoids (letter–2015) http://www.researchgate.net/publication/273330402_The_entourage_effect_Synergistic_actions_of_plant_cannabinoids
What ailments does medical marijuana help? (news–2015) http://www.mnn.com/health/fitness-well-being/stories/what-ailments-does-medical-marijuana-help
Huge New Review Shows What Medical Marijuana May (and May Not) Help (news–2015) https://www.yahoo.com/health/huge-new-review-shows-what-medical-marijuana-may-122209836947.html
MS patients may someday find relief in marijuana chewing gum (news–2015) http://www.marketwatch.com/story/ms-patients-may-someday-find-relief-in-marijuana-chewing-gum-2015-08-17?siteid=rss&rss=1
Sativex in the Management of Multiple Sclerosis-Related Spasticity: Role of the Corticospinal Modulation. (Italy, full, 2015) https://www.hindawi.com/journals/np/2015/656582/
Medicinal cannabis. (Australia, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674028/
Blockade of monoacylglycerol lipase inhibits oligodendrocyte excitotoxicity and prevents demyelination in vivo. (USA, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407719/
Nabilone as an Adjunctive to Gabapentin for Multiple Sclerosis-Induced Neuropathic Pain: A Randomized Controlled Trial. (Canada, full, 2015) https://onlinelibrary.wiley.com/doi/full/10.1111/pme.12569
Effects of pro-inflammatory cytokines on cannabinoid CB1 and CB2 receptors in immune cells. (UK/ USA/ Romania, full, 2015) https://onlinelibrary.wiley.com/doi/full/10.1111/apha.12474
Cannabidiol, a non-psychoactive cannabinoid, leads to EGR2-dependent anergy in activated encephalitogenic T cells. (Israel/ USA, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363052/
A new formulation of cannabidiol in cream shows therapeutic effects in a mouse model of experimental autoimmune encephalomyelitis. (Italy, full, 2015) https://link.springer.com/article/10.1186/s40199-015-0131-8
Narrative review of the safety and efficacy of marijuana for the treatment of commonly state-approved medical and psychiatric disorders. (USA, full, 2015) https://ascpjournal.biomedcentral.com/articles/10.1186/s13722-015-0032-7
Activation of Cannabinoid CB2 receptors Reduces Hyperalgesia in an Experimental Autoimmune Encephalomyelitis Mouse Model of Multiple Sclerosis. (USA, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464808/
The therapeutic potential of cannabinoids for movement disorders. (USA, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357541/
Cannabinoids and Tremor Induced by Motor-related Disorders: Friend or Foe? (Iran/ UK, full, 2015) https://link.springer.com/article/10.1007/s13311-015-0367-5
A sativex-like combination of phytocannabinoids as a disease-modifying therapy in a viral model of multiple sclerosis. (Spain, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507161/
Clinical perspectives on medical marijuana (cannabis) for neurologic disorders. (USA, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549715/
Clinical Use of Cannabinoids for Symptom Control in Multiple Sclerosis. (UK, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604175/
Sativex(®) and clinical-neurophysiological measures of spasticity in progressive multiple sclerosis. (Italy/ Spain, full, 2015) https://www.academia.edu/21225322/Sativex_and_clinical_neurophysiological_measures_of_spasticity_in_progressive_multiple_sclerosis
Purified Cannabidiol, the main non-psychotropic component of Cannabis sativa, alone, counteracts neuronal apoptosis in experimental multiple sclerosis. (Italy, link to PDF, 2015) https://www.europeanreview.org/article/10049
Drug-resistant MS spasticity treatment with Sativex® add-on and driving ability. (Germany, link to PDF, 2015) https://www.researchgate.net/publication/265556600_Drug-resistant_MS_spasticity_treatment_with_SativexR_add-on_and_driving_ability
Neuroprotection in Experimental Autoimmune Encephalomyelitis and Progressive Multiple Sclerosis by Cannabis-Based Cannabinoids. (UK, link to PDF, 2015) https://www.researchgate.net/publication/270004494_Neuroprotection_in_Experimental_Autoimmune_Encephalomyelitis_and_Progressive_Multiple_Sclerosis_by_Cannabis-Based_Cannabinoids
Walking improvements with nabiximols in patients with multiple sclerosis. (Italy, link to PDF, 2015) https://www.researchgate.net/publication/280644357_Walking_improvements_with_nabiximols_in_patients_with_multiple_sclerosis
HU-446 and HU-465, derivatives of the non-psychoactive cannabinoid cannabidiol, decrease the activation of encephalitogenic T cells. (Israel/ India, link to download, 2015) https://www.academia.edu/21241976/HU_446_and_HU_465_derivatives_of_the_non_psychoactive_cannabinoid_cannabidiol_decrease_the_activation_of_encephalitogenic_T_cells
Alteration of delta-6-desaturase (FADS2), secretory phospholipase-A2 (sPLA2) enzymes by Hot-nature diet with co-supplemented hemp seed, evening primrose oils intervention in multiple sclerosis patients. (Iran, link to download, 2015) https://www.semanticscholar.org/paper/Alteration-of-delta-6-desaturase-%28FADS2%29%2C-secretory-Rezapour-Firouzi-Arefhosseini/010f0b614ca6a40237614269a36d2c4ac1626862?p2df
Interaction between the protective effects of cannabidiol and palmitoylethanolamide in experimental model of multiple sclerosis in C57BL/6 mice. (Iran, Abstract, 2015) https://realmofcaring.org/research/interaction-between-the-protective-effects-of-cannabidiol-and-palmitoylethanolamide-in-experimental-model-of-multiple-sclerosis-in-c57bl6-mice/
New quinolone- and 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity. (Italy/ Finland, abstract, 2015) https://www.sciencedirect.com/science/article/abs/pii/S0223523415002937
Effect of Sativex on spasticity-associated symptoms in patients with multiple sclerosis. (Germany, abstract, 2015) https://www.tandfonline.com/doi/abs/10.1586/14737175.2015.1067607
Endocannabinoids in Multiple Sclerosis and Amyotrophic Lateral Sclerosis. (UK, abstract, 2015) https://link.springer.com/chapter/10.1007%2F978-3-319-20825-1_7
Use of Cannabinoids for Spasticity and Pain Management in MS. (USA, abstract, 2015) https://link.springer.com/article/10.1007%2Fs11940-015-0385-y
Effectiveness and Tolerability of THC/CBD Oromucosal Spray for Multiple Sclerosis Spasticity in Italy: First Data from a Large Observational Study. (Italy, abstract, 2015) https://pubmed.ncbi.nlm.nih.gov/26571097/
Efficacy and safety of nabiximols (Sativex®) on multiple sclerosis spasticity in a real-life Italian monocentric study. (Italy, abstract, 2015) https://www.semanticscholar.org/paper/Efficacy-and-safety-of-nabiximols-(Sativex%C2%AE)-on-in-Ferre-Nuara/3de44eca12cb1f92457e31f6cb0f794056b13763
2014
Report On Medical Cannabis Research, What the Science Says (article–2014) http://www.safeaccessnow.org/medical_cannabis_research_what_does_the_evidence_say
Study uncovers marijuana’s potential to treat autoimmune diseases (news–2014) http://www.news-medical.net/news/20140603/Study-uncovers-marijuanas-potential-to-treat-autoimmune-diseases.aspx
2013
Adequate and Well-Controlled Studies Proving Medical Efficacy of Cannabis Exist but Are Ignored by Marijuana Schedulers (news–2013) http://www.huffingtonpost.com/sunil-kumar-aggarwal/marijuana-schedule-1_b_3071725.html
Still Believe Nature Got It Wrong? Top 10 Health Benefits of Marijuana (news–2013) http://www.wakingtimes.com/2013/05/01/still-believe-nature-got-it-wrong-top-10-health-benefits-of-marijuana/
Research shows marijuana can be effectively used to treat multiple sclerosis (news–2013) http://www.naturalnews.com/042498_marijuana_multiple_sclerosis_natural_treatment.html
Medical Marijuana: Consortium of Multiple Sclerosis Centers (news–2013) http://www.msviews.org/msviewsandnews4/index.php/2012%C2%A0-05-28-00-15-54/2012-07-04-00-19-28/610-medical-marajuana-consortium-of-multiple-sclerosis-centers
Aylsham multiple sclerosis sufferer says cannabis-based drug ‘changed my life’ (news-2013) http://www.eveningnews24.co.uk/news/aylsham_multiple_sclerosis_sufferer_says_cannabis_based_drug_changed_my_life_1_2276182
Multiple Sclerosis and Cannabis – A Conversation With Clark French (news–2013) http://www.huffingtonpost.co.uk/jason-reed/multiple-sclerosis-and-cannabis_b_1902151.html
Sending multiple sclerosis up in smoke (news–2013) http://www.eurekalert.org/pub_releases/2013-10/afot-sms100713.php
Chemicals in marijuana ‘protect nervous system’ against MS (news–2013) http://www.medicalnewstoday.com/articles/267161.php
2012
Marijuana Pill Relieves MS and RSD/CRPS Symptoms Plus Pain (news–2012) http://www.rsdinfocenter.com/blog/2012/10/marijuana-pill-relieves-ms-and-rsdcrps-symptoms-plus-pain/
Cannabis-based medications prove effective in relieving pain (news–2012) http://www.news-medical.net/news/20120807/Cannabis-based-medications-prove-effective-in-relieving-pain.aspx
Cannabis Effective for Easing MS Symptoms, but Not for Slowing Progression (news–2012) http://www.prweb.com/releases/-medical-marijuana/-information-san-francisc/prweb9568927.htm
Study: Smoking pot may ease pain, muscle spasms in people with multiple sclerosis (news–2012) http://www.cbsnews.com/news/study-smoking-pot-may-ease-pain-muscle-spasms-in-people-with-multiple-sclerosis/
2010
Nature’s (Legal) Cannabinoids (news-2010) http://www.mapinc.org/drugnews/v10/n126/a04.html?1194
Marijuana and MS–an unfinished story (news-2010) http://www.thefreelibrary.com/Marijuana+and+MS–an+unfinished+story.-a0237205183

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