CANCER - COLON - COLORECTAL

CANCER - COLON - COLORECTAL:

• 2023
• The impact of cannabidiol on intestinal tumorigenesis: A pilot study 0n Caco-2 cell. https://scholarworks.umass.edu/masters_theses_2/1379/ 
• Single-cell analyses revealed cannabidiol rewires tumor microenvironment via inhibiting alternative activation of macrophage and synergizes with anti-PD-1 in colon cancer (in a cell model) https://www.sciencedirect.com/science/article/pii/S2095177923000746?via%3Dihub 
• 2022
• Selective Cytotoxicity of Medical Cannabis (Cannabis Sativa L.) extracts across the whole vegetation cycle under various hydroponic and nutritional treatments. https://pubmed.ncbi.nlm.nih.gov/36459627/ 
• Experience with Medical Marijuana for Cancer Patients in Palliative Setting.https://pubmed.ncbi.nlm.nih.gov/35915672/ 
• Study Explores How Different Marijuana Extracts Kill Types Of Cancer Cells:  https://www.marijuanamoment.net/study-explores-how-different-marijuana-extracts-kill-types-of-cancer-cells/
• The heterogeneity and complexity of Cannabis extracts as antitumor agents:  http://www.oncotarget.com/index.php?
• A randomized trial of medical cannabis (MC) in patients with advanced cancer (AC) to assess impact on opioid use and cancer-related symptoms:  https://ascopubs.org/doi/abs/10.1200/JCO.2019.37.31_suppl.109
• Best 4 Cannabinoids For Treating Cancer: https://www.youtube.com/watch?time_continue=1&v=SrN6vsN5ccc&feature=emb_logo
• 2020
• The Endocannabinoid System: A Target for Cancer Treatment. (Italy, full, 2020) https://www.mdpi.com/1422-0067/21/3/747/htm
• 2019
• Cannabidiol Enhances the Therapeutic Effects of TRAIL by Upregulating DR5 in Colorectal Cancer. (Republic of Korea, full, 2019) https://www.mdpi.com/2072-6694/11/5/642/htm 
• Cannabidiol Overcomes Oxaliplatin Resistance by Enhancing NOS3- and SOD2-Induced Autophagy in Human Colorectal Cancer Cells. (Republic of Korea, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627455/ 
• Down-Regulation of Cannabinoid Type 1 (CB1) Receptor and its Downstream Signaling Pathways in Metastatic Colorectal Cancer. (Italy, full, 2019) https://www.mdpi.com/2072-6694/11/5/708/htm 
• In-hospital outcomes of inflammatory bowel disease in cannabis users: a nationwide propensity-matched analysis in the United States. (USA, full, 2019) http://atm.amegroups.com/article/view/25637/24217 
• Members of the endocannabinoid system are distinctly regulated in inflammatory bowel disease and colorectal cancer. (Austria/ Germany, full, 2019) https://www.nature.com/articles/s41598-019-38865-4 
• Role of Dietary Lipids in Modulating Inflammation through the Gut Microbiota. (USA, full, 2019) https://www.mdpi.com/2072-6643/11/1/117/htm 
• Cannabidiol-from Plant to Human Body: A Promising Bioactive Molecule with MultiTarget Effects in Cancer. (Romania, full, 2019) https://pubmed.ncbi.nlm.nih.gov/31775230/ 
• The Important Role of the Endocannabinoid System and the Endocannabinoidome in Gut Health. (Greece, full, 2019) https://trugen3.com/the-important-role-of-the-endocannabinoid-system-and-the-endocannabinoidome-in-gut-health/ 
• Cannabidiol-induced apoptosis is mediated by activation of Noxa in human colorectal cancer cells. (Republic of Korea, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0304383519300230?via%3Dihub 
• Antiproliferative and antioxidant effect of polar hemp extracts (Cannabis sativa L., Fedora cv.) in human colorectal cell lines. (Italy, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31544542/ 
• Cannabis sativa L. extracts can reverse drug resistance in colorectal carcinoma cells in vitro. (South Africa, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S2213713019300021 
• Cannabinoids: A Guide for Use in the World of Gastrointestinal Disease. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31789770/ 
• 2018
• Rimonabant Kills Colon Cancer Stem Cells without Inducing Toxicity in Normal Colon Organoids. (Italy/ Netherlands, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758598/ 
• Identification of Synergistic Interaction Between Cannabis-Derived Compounds for Cytotoxic Activity in Colorectal Cancer Cell Lines and Colon Polyps That Induces Apoptosis-Related Cell Death and Distinct Gene Expression. (Israel, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038055/ 
• Synthetic Cannabinoid Activity Against Colorectal Cancer Cells. (USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340378/ 
• Interferon γ treatment increases endocannabinoid and related N-acylethanolamine levels in T84 human colon carcinoma cells. (Sweden, click “uclouvainbe” for download, 2018) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Interferon+%CE%B3+treatment+increases+endocannabinoid+and+related+N-acylethanolamine+levels+in+T84+human+colon+carcinoma+cells.&btnG 
• Cannabinoid Receptor-1 Up-regulation in Azoxymethane (AOM)-treated Mice After Dietary Treatment with Quercetin. (Italy, abstract, 2018) http://ar.iiarjournals.org/content/38/8/4485.abstract 
• Cannabinoid pharmacology and therapy in gut disorders. (Spain, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0006295218303186    
• 2017
• Grandmother with terminal cancer jailed for prescribed medical marijuana (news–2017) http://theweek.com/speedreads/696918/grandmother-terminal-cancer-jailed-prescribed-medical-marijuana
• A Mother With Stage 4 Colon Cancer: How Marijuana Helped (news–2017) https://thefreshtoast.com/cannabis/a-mother-with-stage-4-colon-cancer-how-marijuana-helped/#sthash.wTX7QKIa.dpuf
• Medicinal cannabis: Doctors to learn how to prescribe drug at Melbourne course (news–2017) http://www.abc.net.au/news/2017-06-18/doctors-learn-how-to-prescribe-medicinal-cannabis/8622362
• Value of CNRIP1 promoter methylation in colorectal cancer screening and prognosis assessment and its influence on the activity of cancer cells. (China, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701694/ 
• Dietary ω-3 Polyunsaturated Fatty Acids Inhibit Tumor Growth in Transgenic ApcMin/+ Mice, Correlating with CB1 Receptor Up-Regulation. (Italy, full, 2017) https://www.mdpi.com/1422-0067/18/3/485/htm 
• Targeting cannabinoid receptors in gastrointestinal cancers for therapeutic uses: current status and future perspectives. (Italy, full, 2017) https://www.tandfonline.com/doi/full/10.1080/17474124.2017.1367663 
• Value of CNRIP1 promoter methylation in colorectal cancer screening and prognosis asessment and its influence on the activity of cancer cells. (China, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701694/ 
• Inhibition of Wnt/β-Catenin pathway and Histone acetyltransferase activity by Rimonabant: a therapeutic target for colon cancer. (full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601949/ 
• Fatty acid amide hydrolase (FAAH) inhibitor PF-3845 reduces viability, migration and invasiveness of human colon adenocarcinoma Colo-205 cell line: an in vitro study. (Poland, full, 2017) https://ojs.ptbioch.edu.pl/index.php/abp/article/view/1520/1189 
• G protein-coupled receptor GPR55 promotes colorectal cancer and has opposing effects to cannabinoid receptor 1. (Austria/ Germany/ UK, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679368/ 
• Cannabidiol and Palmitoylethanolamide are anti-inflammatory in the acutely inflamed human colon. (UK, click “nottinghamacuk” for download, 2017) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Cannabidiol+and+palmitoylethanolamide+are+anti-inflammatory+in+the+acutely+inflamed+human+colon.%22&btnG 
• Pharmacological inhibition of MAGL lipase attenuates experimental colon carcinogenesis. (Italy, UK/ Spain, abstract, 2017) https://www.sciencedirect.com/science/article/abs/pii/S104366181630932X 
• Power of screening tests for colorectal cancer enhanced by high levels of M2-PK in addition to FOBT. (Italy/ UK, abstract, 2017) https://www.semanticscholar.org/paper/Power-of-screening-tests-for-colorectal-cancer-by-Zaccaro-Saracino/fbd58a806b957d3d9a98503fb7450f1d72aeffe6 
• Cannabinoid Receptors in Regulating the GI Tract: Experimental Evidence and Therapeutic Relevance. (Austria/ Germany, abstract, 2017) https://link.springer.com/chapter/10.1007%2F164_2016_105 
• 2016
• CB2 cannabinoid receptor activation promotes colon cancer progression via AKT/GSK3β signaling pathway. (Spain, full, 2016) https://www.oncotarget.com/article/11968/ 
• RGS proteins as targets in the treatment of intestinal inflammation and visceral pain: New insights and future perspectives. (Poland/ Germany/ USA, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916644/ 
• Endocannabinoids in the gastrointestinal tract. (Republic of Korea/ USA, full, 2016) https://journals.physiology.org/doi/full/10.1152/ajpgi.00294.2015 
• Preclinical and Clinical Assessment of Cannabinoids as Anti-Cancer Agents. (USA/ Egypt, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054289/ 
• The gastrointestinal tract - a central organ of cannabinoid signaling in health and disease. (Austria/ Germany, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130148/ 
• Docosahexaenoyl Serotonin, an endogenously formed n-3 fatty acid-serotonin conjugate has anti-inflammatory properties by attenuating IL-23–IL-17 signalling in macrophages. (Netherlands, abstract, 2016) https://www.semanticscholar.org/paper/Docosahexaenoyl-serotonin%2C-an-endogenously-formed-Poland-Klooster/a86aee234601d1f46a2b9e6ea8d1f3a6e21d90f8 
• Phytochemicals as adjunctive with conventional anticancer therapies. (Iran, abstract, 2016) https://pubmed.ncbi.nlm.nih.gov/27262332/ 
• 2015
• Cannabinoids receptor type 2, CB2, expression correlates with human colon cancer progression and predicts patient survival. (Spain, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381706/ 
• The Antitumor Activity of Plant-Derived Non-Psychoactive Cannabinoids. (USA, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470774/ 
• Endocannabinoid and ceramide levels are altered in patients with colorectal cancer. (China, full, 2015) https://www.spandidos-publications.com/or/34/1/447 
• Anti Proliferative and Pro Apoptotic Effects of Flavonoid Quercetin Are Mediated by CB1 Receptor in Human Colon Cancer Cell Lines. (Italy, click “PDF reader” for full, 2015) https://docksci.com/anti-proliferative-and-pro-apoptotic-effects-of-flavonoid-quercetin-are-mediated_5a51d9b5d64ab289ca8a8ed7.html 
• Endocannabinoids and the Digestive Tract and Bladder in Health and Disease. (UK, partial preview, 2015) https://books.google.com/books?hl=en&lr=&id=QwihCgAAQBAJ&oi=fnd&pg=PA392&ots=FMMqEBDUlA&sig=rRXLCR-WXtY956wHaCOJXuECrT0#v=onepage&q&f=false 
• 2012
• Can Marijuana Stop The Growth Of Colon Cancer Cells? (news–2012) http://www.theweedblog.com/can-marijuana-stop-grown-of-colon-cancer-cells/