EPILEPSY - SEIZURES – Leaf411

EPILEPSY - SEIZURES:

2024
Cannabidiol-enriched oil for patients with drug-resistant epilepsy: Prospective clinical and electrophysiology study. https://pubmed.ncbi.nlm.nih.gov/38808601/
An observational time-series study on the behavioral effects of adjunctive artisanal cannabidiol use by adults with treatment resistant epilepsies. https://link.springer.com/article/10.1186/s12883-024-03646-8
A cost-utility analysis of add-on Cannabidiol versus usual care alone for the treatment of seizures associated with tuberous sclerosis complex in England and Wales. https://pubmed.ncbi.nlm.nih.gov/38441854/
Cannabidiol: metabolism and clinical efficacy in epileptic patients. https://www.tandfonline.com/doi/full/10.1080/17425255.2024.2329733
The longitudinal effects of cannabidiol on brain temperature in patients with treatment-resistant epilepsy. https://pubmed.ncbi.nlm.nih.gov/38199054/
Purified Cannabidiol as add-on therapy in children with treatment-resistant infantile epileptic spasm syndrome. https://pubmed.ncbi.nlm.nih.gov/38237316/
2023
Quality of Life in Angelman Syndrome: A Caregivers' Survey. https://pubmed.ncbi.nlm.nih.gov/37757661/
Real life experience with purified cannabidiol treatment for refractory epilepsy: A multi-center retrospective study. https://www.pedneur.com/article/S0887-8994(23)00362-4/fulltext
Real world evidence on the use of cannabidiol for the treatment of drug resistant epilepsy not related to Lennox-Gastaut syndrome, Dravet syndrome or Tuberous Sclerosis complex. https://pubmed.ncbi.nlm.nih.gov/37769547/
Final analysis of potential drug-drug interactions between highly purified cannabidiol and anti-seizure medications in an open label, expanded access program. https://pubmed.ncbi.nlm.nih.gov/37593907/
Highly purified cannabidiol efficacy and safety in a cohort of adult patient with various types of drug-resistant epilepsies. https://pubmed.ncbi.nlm.nih.gov/37806886/
Highly Purified cannabidiol in the treatment of drug-resistant epilepsies: A real-life impact on seizure frequency, quality of life, behavior and sleep patterns from a single Italian center. https://www.sciencedirect.com/science/article/abs/pii/S1525505023003281
Interview with Dr. Bonni Goldstein-American journal of endocannabinoid medicine. https://www.endocannabinoidmedicine.com/podcasts/963/
An Observational study of Adjunctive Artisanal Cannabidiol Use by Adults with Treatment Resistant Epilepsies: Behavioral and Urinalysis Data. https://www.researchsquare.com/article/rs-3214013/v1
Real-world experience with cannabis as add-on treatment in drug-resistant epilepsy. https://www.seizure-journal.com/article/S1059-1311(23)00193-0/fulltext
The use of cannabinoids in children with epilepsy: a systematic review. https://www.sciencedirect.com/science/article/abs/pii/S1525505023002494
Cannabidiol as adjuvant treatment in adults with drug-resistant focal epilepsy. https://www.sciencedirect.com/science/article/abs/pii/S1525505023001294
Cannabidiol in Children with treatment-resistant epilepsy with myoclonic-atonic seizures. https://www.sciencedirect.com/science/article/abs/pii/S1525505023001646
What are the frequency and risk of adverse events developing in patients with epilepsy who are using CBD?: https://www.news-medical.net/news/20230424/What-are-the-frequency-and-risk-of-adverse-events-developing-in-patients-with-epilepsy-who-are-using-CBD.aspx
Highly purified cannabidiol improves stability and postural tone in adult patients with Lennox-Gastaut Syndrome: A Case Series. https://onlinelibrary.wiley.com/doi/10.1002/epd2.20049
Use of Non-Medical Cannabis in Epilepsy: A scoping Review. https://www.frontiersin.org/articles/10.3389/fneur.2023.1132106/full
A study of mice found that "both CBD alone and CBD+THC in combination might be useful in the treatment of generalized-onset seizures." https://www.sciencedirect.com/science/article/abs/pii/S0920121123000128
2022
Long term efficacy and safety of cannabidiol in patients with treatment-resistant epilepsies: 4 year results from the expanded access program. (Szaflarski, et al, 2022). https://onlinelibrary.wiley.com/doi/abs/10.1111/epi.17496
10 ways medical marijuana can be used to treat disease (news-2015) http://www.cnn.com/2015/04/15/health/marijuana-medical-advances/index.html
Overview of cannabidiol (CBD) and its analogues: Structures, biological activities, and neuroprotective mechanisms in epilepsy and Alzheimer’s disease: https://www.sciencedirect.com/science/article/abs/pii/S0223523420301306?via%3Dihub
Cannabis-based products for pediatric epilepsy: An updated systematic review: https://www.sciencedirect.com/science/article/abs/pii/S1059131119307332
CANNABIS INSTEAD OF POLYPHARMACY? Could cannabis be the safer alternative prescribers and patients are looking for? https://www.projectcbd.org/medicine/cannabis-instead-polypharmacy?utm_source=Project%20CBD%20Mailing%20List&utm_campaign=16009440cf-EMAIL_CAMPAIGN_2019_11_18_03_47&utm_medium=email&utm_term=0_ea5031784e-16009440cf-11562609

2021
Seizures Among Children Treated with Whole-Plant Cannabis Fall 86%: https://www.ganjapreneur.com/seizures-among-children-treated-with-whole-plant-cannabis-fall-86/?utm_source=newsletter&utm_medium=email&utm_campaign=malta_becomes_eus_first_to_legalize_cannabis_seizures_fall_86_for_kids_treated_with_whole_plant_cannabis_and_more&utm_term=2021-12-15
2020
Phytocannabinoids in Neurological Diseases: Could They Restore a Physiological GABAergic Transmission? (Italy/ Netherlands, full, 2020) https://www.mdpi.com/1422-0067/21/3/723/htm
Medical Cannabis for Intractable Epilepsy in Childhood: A Review. (Israel, link to download, 2020) https://www.rmmj.org.il/userimages/1024/1/PublishFiles/1029Article.pdf
Medical Cannabis in Children. (Israel, link to download, 2020) https://www.rmmj.org.il/userimages/1010/1/PublishFiles/1026Article.pdf
Cannabis-based products for pediatric epilepsy: An updated systematic review. (Canada, abstract, 2020) https://pubmed.ncbi.nlm.nih.gov/31865133/
The Use of Cannabis as a Treatment for Epilepsy in Adult Patients: Are Side Effects a Limitation of Use? (Canada/ Colombia, abstract, 2020) https://pubmed.ncbi.nlm.nih.gov/31895185/
The Endocannabinoid System and Synthetic Cannabinoids in Preclinical Models of Seizure and Epilepsy. (Canada, abstract, 2020) https://pubmed.ncbi.nlm.nih.gov/31895186/
A North American History of Cannabis Use in the Treatment of Epilepsy. (Canada, abstract, 2020) https://pubmed.ncbi.nlm.nih.gov/31895188/
Cannabis for Pediatric Epilepsy. (Canada/ USA, abstract, 2020) https://pubmed.ncbi.nlm.nih.gov/31895184/
The cannabidiol conundrum: potential benefits and risks of cannabidiol products for children. (USA, abstract, 2020) https://pubmed.ncbi.nlm.nih.gov/31833952/
The role of cannabinoids in epilepsy treatment: a critical review of efficacy results from clinical trials. (France/ USA, abstract, 2020) https://pubmed.ncbi.nlm.nih.gov/31916540/
The anticonvulsant effects of cannabidiol in experimental models of epileptic seizures: From behavior and mechanisms to clinical insights. (Brazil, abstract, 2020) https://www.sciencedirect.com/science/article/abs/pii/S014976341931067X
The other side of the leaf: Seizures associated with synthetic cannabinoid use. (Australia, abstract, 2020) https://www.epilepsybehavior.com/article/S1525-5050(19)31190-4/fulltext
2019
Why I campaign for children like my son Alfie Dingley to be able to get medical
cannabis (full–2019) https://www.bmj.com/content/365/bmj.l1921.long
Cannabis dosage studied to reduce seizures in children with severe epilepsy (news/abst–2019) https://neurosciencenews.com/epilepsy-cannabis-dose-14431/
Cannabis-based products for pediatric epilepsy: A systematic review. (Canada, full, 2019) https://onlinelibrary.wiley.com/doi/full/10.1111/epi.14608
Are there mortality risks for patients with epilepsy who use cannabis treatments as monotherapy? (USA, full, 2019) https://www.sciencedirect.com/science/article/pii/S2213323218301567
Epidiolex as adjunct therapy for treatment of refractory epilepsy: a comprehensive review with a focus on adverse effects. (USA, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396837/
Cost-effectiveness of cannabinoids for pediatric drug-resistant epilepsy: protocol for a systematic review of economic evaluations. (Canada, full, 2019) https://systematicreviewsjournal.biomedcentral.com/articles/10.1186/s13643-019-0990-z#Abs1
Medicinal use of cannabis based products and cannabinoids. (UK, full clinical update, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447998/
Single and Synergistic Effects of Cannabidiol and Δ-9-Tetrahydrocannabinol on Zebrafish Models of Neuro-Hyperactivity. (Canada, full, 2019) https://www.frontiersin.org/articles/10.3389/fphar.2019.00226/full
Use of Cannabidiol in the Treatment of Epilepsy: Efficacy and Security in Clinical Trials. (Italy, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514832/
Pharmacokinetics and Tolerability of Multiple Doses of Pharmaceutical-Grade Synthetic Cannabidiol in Pediatric Patients with Treatment-Resistant Epilepsy. (USA/ Belgium, full, 2019) https://link.springer.com/article/10.1007%2Fs40263-019-00624-4
Dravet Syndrome: An Overview. (USA, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713249/
Cannabidiol reduces seizures following CNS infection with Theiler's murine encephalomyelitis virus. (USA, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698680/
Ontogeny and programming of the fetal temporal cortical endocannabinoid system by moderate maternal nutrient reduction in baboons (Papio spp.). (USA, full, 2019) https://physoc.onlinelibrary.wiley.com/doi/full/10.14814/phy2.14024
Coadministered cannabidiol and clobazam: Preclinical evidence for both pharmacodynamic and pharmacokinetic interactions. (Australia, full, 2019) https://onlinelibrary.wiley.com/doi/full/10.1111/epi.16355
American Epilepsy Society (AES): Written Comments to Norman E. “Ned” Sharpless, MD, Acting Commissioner of Food and Drugs, U.S. Food and Drug Administration (FDA), Department of Health and Human Services (HHS): on Docket ID# FDA-2019-N1482, Scientific Data and Information about Products Containing Cannabis or CannabisDerived Compounds; Public Hearing; Request for Comments: Submitted on: July 16, 2019. (USA, full, 2019) https://journals.sagepub.com/doi/full/10.1177/1535759719878716?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed&
Cannabidiol. (USA, full, 2019) https://www.ncbi.nlm.nih.gov/books/NBK548890/
A preliminary study of the effects of cannabidiol (CBD) on brain structure in patients with epilepsy. (USA, full, 2019) https://www.sciencedirect.com/science/article/pii/S258998641930111X
The Interplay between the Endocannabinoid System, Epilepsy and Cannabinoids. (Australia, full, 2019) https://www.mdpi.com/1422-0067/20/23/6079/htm
Effects of CBD-Enriched Cannabis sativa Extract on Autism Spectrum Disorder Symptoms: An Observational Study of 18 Participants Undergoing Compassionate Use. (Brazil, full, 2019) https://www.frontiersin.org/articles/10.3389/fneur.2019.01145/full
Cannabidiol attenuates seizures and EEG abnormalities in Angelman syndrome model mice. (USA, full, 2019) https://www.jci.org/articles/view/130419
Cannabis Influences the Putative Cytokines-Related Pathway of Epilepsy among Egyptian Epileptic Patients. (Egypt/ Germany, link to PDF, 2019) https://www.mdpi.com/2076-3425/9/12/332
Investigating the Therapeutic Mechanism of Cannabidiol in a Human Induced Pluripotent Stem Cell (iPSC)-Based Cellular Model of Dravet Syndrome. (USA, download, 2019) http://symposium.cshlp.org/content/early/2019/06/11/sqb.2018.83.038174.long
Crossing the Line: Care of a Pediatric Patient with Intractable Seizures and Severe Neuropathic Pain in Absence of Access to Medical Marijuana. (USA, link to download, 2019) https://www.cedfoundation.com/wp-content/uploads/2019/06/Crossing-the-Line-Care-of-a-Pediatric-Patient-with-Intractable-Seizures-and-Severe-Neuropathic-Pain-in-Absence-of-Access-to-Medical-Marijuana.pdf
Why medical cannabis is still out of patients' reach-an essay by David Nutt. (UK, click “drugscience” for download, 2019) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Why+medical+cannabis+is+still+out+of+patients%27+reach-an+essay+by+David+Nutt.&btnG
Cannabis-based treatments as an alternative remedy for epilepsy. (USA, article, 2019) https://www.sciencedirect.com/science/article/pii/S221342201930157X
Cannabidiol: A New Hope for Patients With Dravet or Lennox-Gastaut Syndromes. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/30616356/
Cannabinoid therapy in epilepsy. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/30676535/
A Review of Human Studies Assessing Cannabidiol's (CBD) Therapeutic Actions and Potential. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/30730563/
Cannabis for refractory epilepsy in children: A review focusing on CDKL5 Deficiency Disorder. (Australia/ USA, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0920121118306107
Improving post-hypoxic myoclonus using cannabidiol. (USA, abstract, 2019) https://www.seizure-journal.com/article/S1059-1311(18)30573-9/fulltext
Safety, efficacy, and mechanisms of action of cannabinoids in neurological disorders. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/30910443/
Cannabidiol as adjunctive treatment of seizures associated with Lennox-Gastaut syndrome and Dravet syndrome. (Italy/ Austria, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/30938373/
Disposition of oral delta-9 tetrahydrocannabinol (THC) in children receiving cannabis extracts for epilepsy. (USA, abstract, 2019) https://www.tandfonline.com/doi/abs/10.1080/15563650.2019.1616093?journalCode=ictx20&
Medical Marijuana in the Pediatric Population With Epilepsy-What You Should Know. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31160106/
Food effect on pharmacokinetics of cannabidiol oral capsules in adult patients with refractory epilepsy. (USA, abstract, 2019) https://onlinelibrary.wiley.com/doi/abs/10.1111/epi.16093
Marijuana use among patients with epilepsy at a tertiary care center. (USA, abstract, 2019) https://www.epilepsybehavior.com/article/S1525-5050(19)30222-7/fulltext
Pharmacological and Therapeutic Properties of Cannabidiol for Epilepsy. (Italy, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31372958/
Knowledge, expectations and fears of cannabis use of epilepsy patients at a tertiary epilepsy center. (Germany, abstract, 2019) https://www.epilepsybehavior.com/article/S1525-5050(19)30538-4/fulltext
Drug–drug interactions and pharmacodynamics of concomitant clobazam and cannabidiol or stiripentol in refractory seizures. (USA, abstract, 2019) https://www.epilepsybehavior.com/article/S1525-5050(19)30449-4/fulltext
Early endocannabinoid system activation attenuates behavioral impairments induced by initial impact but does not prevent epileptogenesis in lithium–pilocarpine status epilepticus model. (Russia, abstract, 2019) https://www.epilepsybehavior.com/article/S1525-5050(18)30727-3/fulltext
Piperidine and piperazine inhibitors of fatty acid amide hydrolase targeting excitotoxic pathology. (USA, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0968089619310235?via%3Dihub
Clinical trial simulations of the interaction between cannabidiol and clobazam and effect on drop-seizure frequency. (Netherlands, abstract, 2019) https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bcp.14158
Cannabinoids, hippocampal excitability and efficacy for the treatment of epilepsy. (Israel, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0163725819301093
Pharmacokinetics of Phytocannabinoid Acids and Anticonvulsant Effect of Cannabidiolic Acid in a Mouse Model of Dravet Syndrome. (Australia, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31686510/
Cannabidiol: Recent advances and new insights for neuropsychiatric disorders treatment. (Italy/ Sweden, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0024320519302176
Medicinal cannabis in Latin America: History, current state of regulation, and the role of the pharmacist in a new clinical experience with cannabidiol oil. (Argentina, abstract, 2019) https://www.sciencedirect.com/science/article/pii/S1544319119304285
Cannabidiol: A Review of Clinical Efficacy and Safety in Epilepsy. (USA, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0887899418311688
Efficacy and adverse event profile of cannabidiol and medicinal cannabis for treatment-resistant epilepsy: Systematic review and meta-analysis. (Brazil, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31731110/
Epileptic Spikes in EEG and Migraine Attacks in the Course of Cannabis Withdrawal: A Case Report. (Germany, abstract, 2019) https://journals.sagepub.com/doi/abs/10.1177/1550059419886704?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&journalCode=eegb&
Reduced cannabinoid 2 receptor activity increases susceptibility to induced seizures in mice. (USA, abstract, 2019) https://onlinelibrary.wiley.com/doi/abs/10.1111/epi.16388
Cannabinoids for drug-resistant seizures in a critically ill patient-Case report and literature review. (Australia, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31770462/
The use of medical grade cannabis in Italy for drug-resistant epilepsy: a case series. (Italy, abstract, 2019) https://link.springer.com/article/10.1007/s10072-019-04162-1
A perspective on cannabinoids for treating epilepsy: do they really change the landscape? (UK, abstract, 2019) https://www.sciencedirect.com/science/article/pii/S0028390819304277?via%3Dihub
Synthetic pharmaceutical grade cannabidiol for treatment of refractory infantile spasms: A multicenter phase-2 study. (USA/ Belgium, abstract, 2019) https://www.epilepsybehavior.com/article/S1525-5050(19)30916-3/fulltext
Cannabinoids and the expanded endocannabinoid system in neurological disorders. (Italy/ Canada, abstract, 2019) https://www.nature.com/articles/s41582-019-0284-z
Exploiting cannabinoid and vanilloid mechanisms for epilepsy treatment. (Brazil, abstract, 2019) https://www.epilepsybehavior.com/article/S1525-5050(19)30373-7/fulltext
Potential role of cannabidiol for seizure control in a patient with recurrent glioma. (Australia, abstract, 2019) https://www.jocn-journal.com/article/S0967-5868(19)31306-2/fulltext
Synthetic cannabinoid receptor agonists-induced recurrent seizure in elderly patient. (USA, abstract, 2019) https://www.ajemjournal.com/article/S0735-6757(19)30752-1/fulltext
2018
The Path to the First FDA-Approved Cannabis-Derived Treatment and What Comes
Next (click “cha(dot)com” for download-2018) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22The+Path+to+the+First+FDA-Approved+CannabisDerived+Treatment+and+What+Comes+Next%22&btnG
Why marijuana is headed for the mainstream. (article – 2018)
https://www.managedcaremag.com/linkout/2018/12/31
Cannabis, cannabis everywhere: UK to review medical cannabis policy as Canada plans
imminent legalisation for all uses. (1st page – 2018)
https://www.bmj.com/content/361/bmj.k2695.long
Is Marijuana the World’s Most Effective Treatment for Autism? (news – 2018)
https://www.newsweek.com/2018/02/23/really-good-weed-why-cannabis-may-be-worlds-most-effective-remedy-core-806758.html
First FDA-Approved Drug Made From Cannabis Can’t Be Sold In Colorado.
(news – 2018) https://denver.cbslocal.com/2018/04/13/cannabis-fda-state-capitol/
The FDA Approved its First Cannabis Drug. What Next? (news – 2018)
https://www.wired.com/story/the-fda-approved-its-first-cannabis-drug-what-next/
Colombia’s Billion-Dollar ‘Marijuana Legacy’ Bonanza. (news – 2018)
https://www.telesurenglish.net/news/Colombias-Billion-Dollar-Marijuana-Legacy-Bonanza-20180504-0017.html
Efficacy of artisanal preparations of cannabidiol for the treatment of epilepsy: Practical experiences in a tertiary medical center. (USA, full, 2018) https://www.epilepsybehavior.com/article/S1525-5050(18)30009-X/fulltext
Cannabidiol Regulates Long Term Potentiation Following Status Epilepticus: Mediation by Calcium Stores and Serotonin. (Israel, full, 2018) https://www.frontiersin.org/articles/10.3389/fnmol.2018.00032/full
Positron emission tomography imaging of cerebral glucose metabolism and type 1 cannabinoid receptor availability during temporal lobe epileptogenesis in the amygdala kindling model in rhesus monkeys. (Belgium, full, 2018) https://onlinelibrary.wiley.com/doi/full/10.1111/epi.14059
Therapeutic potential of medicinal marijuana: an educational primer for health care professionals. (Canada, full, 2018) https://www.dovepress.com/therapeutic-potential-of-medicinal-marijuana-an-educational-primer-for-peer-reviewed-fulltext-article-DHPS
Cannabis in epilepsy: From clinical practice to basic research focusing on the possible role of cannabidivarin. (Italy/ Netherlands, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719834/
Antiepileptogenic Effect of Subchronic Palmitoylethanolamide Treatment in a Mouse Model of Acute Epilepsy. (Germany, full, 2018) https://www.frontiersin.org/articles/10.3389/fnmol.2018.00067/full
Review of the neurological benefits of phytocannabinoids. (USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938896/
Composition and Use of Cannabis Extracts for Childhood Epilepsy in the Australian Community. (Australia, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033872/
Cannabis for pediatric epilepsy: protocol for a living systematic review. (Canada, full, 2018) https://systematicreviewsjournal.biomedcentral.com/articles/10.1186/s13643-018-0761-2
Evidence for THC versus CBD in cannabinoids. (Canada, full, 2018) https://www.cfp.ca/content/64/7/519.long
Therapeutic Use of medicinal cannabis in difficult to manage epilepsy. (Australia, full, 2018) https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bcp.13711
Cannabidiol enhances morphine antinociception, diminishes NMDA-mediated seizures and reduces stroke damage via the sigma 1 receptor. (Spain, full, 2018) https://molecularbrain.biomedcentral.com/articles/10.1186/s13041-018-0395-2
Potential Clinical Benefits of CBD-Rich Cannabis Extracts Over Purified CBD in Treatment-Resistant Epilepsy: Observational Data Meta-analysis. (Brazil, full, 2018) https://www.frontiersin.org/articles/10.3389/fneur.2018.00759/full
Cannabidiol for Treatment of Childhood Epilepsy-A Cross-Sectional Survey. (Germany/ Spain, full, 2018) https://www.frontiersin.org/articles/10.3389/fneur.2018.00731/full
Translational Investigation of the Therapeutic Potential of Cannabidiol (CBD): Toward a New Age. (Brazil, full, 2018) https://www.frontiersin.org/articles/10.3389/fimmu.2018.02009/full
The spatiotemporal expression changes of CB2R in the hippocampus of rats following pilocarpine-induced status epilepticus. (China, full, 2018) https://www.sciencedirect.com/science/article/pii/S0920121118302201?via%3Dihub
Efficacy of cannabinoids in paediatric epilepsy. (New Zealand/ Australia, full, 2018) https://onlinelibrary.wiley.com/doi/full/10.1111/dmcn.14087
A prospective open-label trial of a CBD/THC cannabis oil in dravet syndrome. (Canada, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144444/
Cannabis Therapeutics and the Future of Neurology. (USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200872/
Epilepsy and Cannabis: A Literature Review. (Pakistan/ USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235654/
Evidence for cannabis and cannabinoids for epilepsy: a systematic review of controlled and observational evidence. (Australia/ UK, full, 2018) https://jnnp.bmj.com/content/89/7/741.long
Effect of Cannabidiol on Drop Seizures in the Lennox-Gastaut Syndrome. (USA/ UK/ Spain, full, 2018) https://www.nejm.org/doi/full/10.1056/NEJMoa1714631
Cannabidiol for Epilepsy: New Hope on the Horizon? (USA, full, 2018) https://www.clinicaltherapeutics.com/article/S0149-2918(18)30325-4/fulltext
Cannabis Oil in an Irish Children’s Critical Care Unit. (Ireland, full, 2018) http://imj.ie/cannabis-oil-in-an-irish-childrens-critical-care-unit/
Treatment of infantile spasms. (USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293071/
Plants come to mind: phytocannabinoids, endocannabinoids and the control of seizures. (USA, full, 2018) https://onlinelibrary.wiley.com/doi/full/10.1111/add.14540
Efficacy of CBD-enriched medical cannabis for treatment of refractory epilepsy in children and adolescents - An observational, longitudinal study. (Israel, full, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0387760418301128
Simultaneous lipidomic and transcriptomic profiling in mouse brain punches of acute epileptic seizure model compared to controls. (Germany/ Netherlands, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794423/
Neuroprotective Action of the CB1/2 Receptor Agonist, WIN 55,212-2, against DMSO but Not Phenobarbital-Induced Neurotoxicity in Immature Rats. (USA, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318010/
Anticonvulsant and Neuroprotective Effects of Cannabidiol During the Juvenile Period. (USA, full, 2018) https://academic.oup.com/jnen/article/77/10/904/5085875
Cannabis for the treatment of paediatric epilepsy? An update for Canadian paediatricians. (Canada/ Israel, full, 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234422/
Pharmacological characterization of the cannabinoid receptor 2 agonist, β-caryophyllene on seizure models in mice. (Brazil/ Bulgaria, full, 2018) https://www.sciencedirect.com/science/article/pii/S1059131117306118
Cannabis and epilepsy. (UK/ Ireland, full, 2018) https://pn.bmj.com/content/18/6/465.long
Prospects of Cannabidiol for Easing Status Epilepticus-Induced Epileptogenesis and Related Comorbidities. (USA/ India/ Brazil, link to PDF, 2018) https://www.researchgate.net/publication/322709612_Prospects_of_Cannabidiol_for_Easing_Status_Epilepticus-Induced_Epileptogenesis_and_Related_Comorbidities
Cannabis for the Treatment of Epilepsy: an Update. (Canada, link to PDF, 2018) https://www.researchgate.net/publication/324263327_Cannabis_for_the_treatment_of_paediatric_epilepsy_An_update_for_Canadian_paediatricians
Practical considerations in medical cannabis administration and dosing. (Canada/ Czech Republic, link to PDF, 2018) https://www.researchgate.net/publication/322257368_Practical_considerations_in_medical_cannabis_administration_and_dosing
Species-specific susceptibility to cannabis-induced convulsions. (UK/ Ireland/ USA, download, 2018) http://centaur.reading.ac.uk/75676/9/Whalley_et_al-2017-British_Journal_of_Pharmacology.pdf
The Path to the First FDA-Approved Cannabis-Derived Treatment and What Comes Next. (USA, link to article, 2018) https://cha.com/wp-content/uploads/2018/10/3.5.5-jama_Rubin_2018_mn_180050-1.pdf
Cannabinoids: just like any other medication? (UK, article, 2018) https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)31611-8/fulltext
Safety of cannabidiol prescribed for children with refractory epilepsy. (Italy, letter, 2018) https://www.mja.com.au/journal/2018/209/5/safety-cannabidiol-prescribed-children-refractory-epilepsy
Arvanil, olvanil, AM 1172 and LY 2183240 (various cannabinoid CB1 receptor agonists) increase the threshold for maximal electroshock-induced seizures in mice. (Poland, abstract, 2018) https://www.semanticscholar.org/paper/Arvanil%2C-olvanil%2C-AM-1172-and-LY-2183240-(various-Tutka-Wla%C5%BA/7a78fa93122b8296e83888c29e0ab5325d2fb6fd
Medical cannabis: “restrictive” guidance lets patients down, say campaigners. (UK, abstract, 2018) https://www.bmj.com/content/363/bmj.k4654.full
Intoxication From Accidental Marijuana Ingestion in Pediatric Patients: What May Lie Ahead. (USA, Case report, abstract, 2018) https://pubmed.ncbi.nlm.nih.gov/29406477/
Control of excessive neural circuit excitability and prevention of epileptic seizures by endocannabinoid signaling. (Japan, abstract, 2018) https://link.springer.com/article/10.1007/s00018-018-2834-8
Endocannabinoid CB1 receptors are involved in antiepileptogenic effect of low frequency electrical stimulation during perforant path kindling in rats. (Iran, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0920121117304291?via%3Dihub
Investigational cannabinoids in seizure disorders, what have we learned thus far? (Serbia, abstract, 2018) https://pubmed.ncbi.nlm.nih.gov/29842819/
TRPV1 mediates the anticonvulsant effects of acetaminophen in mice. (Japan, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0920121118300573
Efficacy and Safety of Adjunctive Cannabidiol in Patients with Lennox-Gastaut Syndrome: A Systematic Review and Meta-Analysis. (Italy, abstract, 2018) https://link.springer.com/article/10.1007%2Fs40263-018-0558-9
Cannabinoid signalling in the immature brain: Encephalopathies and neurodevelopmental disorders. (Spain/ Italy, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S0006295218303344
Inhibitions of anandamide transport and FAAH synthesis decrease apoptosis and oxidative stress through inhibition of TRPV1 channel in an in vitro seizure model. (Turkey, abstract, 2018) https://link.springer.com/article/10.1007/s11010-018-3439-0
Acute foot-shock stress decreased seizure susceptibility against pentylenetetrazole induced seizures in mice: Interaction between endogenous opioids and cannabinoids. (Iran/ Canada/ USA, abstract, 2018) https://www.epilepsybehavior.com/article/S1525-5050(17)30777-1/fulltext
Efficacy and Safety of Cannabidiol in Epilepsy: A Systematic Review and MetaAnalysis. (Italy/ Austria/ Switzerland, abstract, 2018) https://link.springer.com/article/10.1007%2Fs40265-018-0992-5
Medical cannabis: A needs analysis for people with epilepsy. (Australia, abstract, 2018) https://www.sciencedirect.com/science/article/abs/pii/S1744388118302354
The US Food and Drug Administration’s Authorization of the First Cannabis-Derived Pharmaceutical - Are We Out of the Haze? (USA, abstract, 2018) https://jamanetwork.com/journals/jamaneurology/article-abstract/2714720
The level of evidence of medical marijuana use for treating disabilities: a scoping review. (USA, abstract, 2018) https://www.tandfonline.com/doi/abs/10.1080/09638288.2018.1523952
Simultaneous quantification of thirteen cannabinoids and metabolites in human plasma by liquid chromatography tandem mass spectrometry in adult epilepsy patients. (USA, abstract, 2018) https://www.semanticscholar.org/paper/Simultaneous-Quantification-of-13-Cannabinoids-and-Roslawski-Remmel/bbfd94b9acff825e7108939c8fb28fa9e2905f43
2017
In Peru, mothers rouse support for legalizing medical marijuana (news–2017) https://www.yahoo.com/news/peru-mothers-rouse-support-legalizing-medical-marijuana-171133311.html
Cannabis-based medicine may cut seizures in half for those with tough-to-treat epilepsy (news–2017) https://www.sciencedaily.com/releases/2017/04/170418161907.htm
Medical marijuana prescribed to 11-year-old boy on the NHS in first case of its kind (news–2017) http://www.telegraph.co.uk/news/2017/04/23/medicalmarijuana-prescribed-11-year-old-nhs-first-time/amp/
Cannabis Gives 4-Year-Old a Shot at Life After Family’s Cross-Country Move (news–2017) https://www.yahoo.com/news/4-year-old-done-drugs-anyone-know-095149048.html
Why I’m Growing Weed: The absurdity of Georgia’s medical marijuana law (news–2017) http://www.citypaper.com/blogs/feedbag/bcpnews-why-i-m-growing-weed-the-absurdity-of-georgia-s-medical-marijuana-law-20170421-story.html
The Compelling Case for Treating Autism with Marijuana (news–2017) https://tonic.vice.com/en_us/article/the-compelling-case-for-treating-autism-with-marijuana
Dosing THCA: Less is more (news–2017) http://www.alternet.org/drugs/dosing-thca-less-more
Medical Marijuana for Seizures (news–2017) https://www.projectcbd.org/article/medical-marijuana-seizures-sulak-saneto-goldstein
Chelsea Leyland’s Big Crusade for Cannabis (news–2017) http://www.harpersbazaar.com/culture/features/a9640704/chelsea-leyland-medical-marijuana-cbd-oil/
NEUROSCIENCE: THE STUDY AND APPLICATION OF CANNABIS MEDICINES (news–2017) http://www.greenbridgemed.com/neuroscience-cannabis-medicine/
Family hopes marijuana compound will stop child’s seizures. (news – 2017)
https://www.usatoday.com/story/news/nation-now/2017/08/05/cannabidiol-drug-trial/536889001/
To save her daughter, this mom became a medical marijuana pioneer. (news – 2017)
https://www.salon.com/2017/09/03/to-save-her-daughter-this-mom-became-a-medical-marijuana-pioneer_partner/
Protective Effects of Cannabidiol against Seizures and Neuronal Death in a Rat Model of Mesial Temporal Lobe Epilepsy. (Brazil, full, 2017) https://www.frontiersin.org/articles/10.3389/fphar.2017.00131/full
A Long-Term Treatment with Arachidonyl-2'-Chloroethylamide Combined with Valproate Increases Neurogenesis in a Mouse Pilocarpine Model of Epilepsy. (USA, full, 2017) https://www.mdpi.com/1422-0067/18/5/900/htm
Cannabinoids in Pediatrics. (USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473390/
Could Cannabidiol be a Treatment Option for Intractable Childhood and Adolescent Epilepsy? (Republic of Korea, full, 2017) https://www.j-epilepsy.org/journal/view.php?year=2017&vol=7&page=16
Modulation of Astrocyte Activity by Cannabidiol, a Nonpsychoactive Cannabinoid. (Israel, full, 2017) https://www.mdpi.com/1422-0067/18/8/1669/htm
An Australian nationwide survey on medicinal cannabis use for epilepsy: History of antiepileptic drug treatment predicts medicinal cannabis use. (Australia, full, 2017) https://www.epilepsybehavior.com/article/S1525-5050(17)30073-2/fulltext
Effects of arachidonyl-2'-chloroethylamide (ACEA) on the protective action of various antiepileptic drugs in the 6-Hz corneal stimulation model in mice. (Poland, full, 2017) https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0183873
Addressing sufficiency of the CB1 receptor for endocannabinoid-mediated functions through conditional genetic rescue in forebrain GABAergic neurons. (Germany, full, 2017) https://link.springer.com/article/10.1007%2Fs00429-017-1411-5
The FAAH inhibitor URB597 suppresses hippocampal maximal dentate afterdischarges and restores seizure-induced impairment of short and long-term synaptic plasticity. (Italy/ Malta/ UK, full, 2017) https://www.nature.com/articles/s41598-017-11606-1
Report from a Survey of Parents Regarding the Use of Cannabidiol (Medicinal cannabis) in Mexican Children with Refractory Epilepsy. (Mexico, full report, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368357/
The Role of BK Channels in Antiseizure Action of the CB1 Receptor Agonist ACEA in Maximal Electroshock and Pentylenetetrazole Models of Seizure in Mice. (Iran, full, 2017)
Cannabinoid antagonist SLV326 induces convulsive seizures and changes in the interictal EEG in rats. (Netherlands/ Russia/ Germany, full, 2017) https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0165363
A spicy status: Synthetic cannabinoid (spice) use and new-onset refractory status epilepticus—A case report and review of the literature. (USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721953/
Rare genetic variants in the endocannabinoid system genes CNR1 and DAGLA are associated with neurological phenotypes in humans. (USA, full, 2017) https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0187926
Do Cannabinoids Confer Neuroprotection Against Epilepsy? An Overview. (Italy, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738750/
Cannabinoids in the Treatment of Epilepsy: Hard Evidence at Last? (Italy, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767492/
Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome. (USA, full, 2017) https://www.nejm.org/doi/10.1056/NEJMoa1611618?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dwww.ncbi.nlm.nih.gov
Inhibition of monoacylglycerol lipase terminates diazepam-resistant status epilepticus in mice and its effects are potentiated by a ketogenic diet. (Italy/ USA, full, 2017) https://onlinelibrary.wiley.com/doi/full/10.1111/epi.13950
Anticonvulsant effect of cannabinoid receptor agonists in models of seizures in developing rats. (USA, full, 2017) https://onlinelibrary.wiley.com/doi/full/10.1111/epi.13842
Cannabinoids for epilepsy: What do we know and where do we go? (UK/ Sweden, abstract, 2017) https://onlinelibrary.wiley.com/doi/full/10.1111/epi.13973
Medical Cannabinoids in Children and Adolescents: A Systematic Review. (USA, full, 2017) https://pediatrics.aappublications.org/content/140/5/e20171818.long
Fatty acid amide hydrolase inhibitor URB597 may protect against kainic acid-induced damage to hippocampal neurons: Dependence on the degree of injury. (Russia, full, 2017) https://www.nature.com/articles/s41598-017-11606-1
Therapeutic effects of cannabinoids in animal models of seizures, epilepsy, epileptogenesis, and epilepsy-related neuroprotection. (UK/ USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651410/
Cannabinoid receptor 1/2 double-knockout mice develop epilepsy. (USA/ Brazil, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716894/
Antiepileptic drugs in clinical development: differentiate or die? (Germany/ Italy, link to PDF, 2017) https://www.researchgate.net/publication/319086508_Antiepileptic_Drugs_in_Clinical_Development_Differentiate_or_Die
Cannabinoids in treatment-resistant epilepsy: A review. (Spain, link to PDF, 2017) https://www.researchgate.net/publication/313492542_Cannabinoids_in_treatment-resistant_epilepsy_A_review
The Direct Actions of Cannabidiol and 2-Arachidonoyl Glycerol at GABAA Receptors. (Australia, link to PDF, 2017) https://www.researchgate.net/publication/314109989_The_Direct_Actions_of_Cannabidiol_and_2-Arachidonoyl_Glycerol_at_GABAA_Receptors
Endocannabinoid-dependent protection against kainic acid-induced long-term alteration of brain oscillations in guinea pigs. (Russia, link to PDF, 2017) https://www.researchgate.net/publication/313573682_Endocannabinoid-dependent_protection_against_kainic_acid-induced_long-term_alteration_of_brain_oscillations_in_guinea_pigs
Anticonvulsant effect of cannabidiol in the pentylenetetrazole model: Pharmacological mechanisms, electroencephalographic profile, and brain cytokine levels. (Brazil, abstract, 2017) https://www.sciencedirect.com/science/article/abs/pii/S1525505017303220
Neurological aspects of medical use of cannabidiol. (Italy, abstract, 2017) https://www.ingentaconnect.com/contentone/ben/cnsnddt/2017/00000016/00000005/art00006
Neuronal nitric oxide synthase is involved in CB/TRPV1 signalling: Focus on control of hippocampal hyperexcitability. (Italy, abstract, 2017) https://www.sciencedirect.com/science/article/abs/pii/S0920121117303650
Interaction between urethane and cannabinoid CB1 receptor agonist and antagonist in penicillin-induced epileptiform activity. (Turkey, click “Free Full PDF” for download, 2017) https://pubmed.ncbi.nlm.nih.gov/28691717/
Cannabis use in Epilepsy. Current situation in Argentina and abroad. (Argentina, abstract, 2017) https://pubmed.ncbi.nlm.nih.gov/28898306/
Historical perspective on the medical use of cannabis for epilepsy: Ancient times to the 1980s. (USA, abstract, 2017) https://www.epilepsybehavior.com/article/S1525-5050(16)30666-7/fulltext
Neuroimaging studies towards understanding the central effects of pharmacological cannabis products on patients with epilepsy. (USA, abstract, 2017) https://www.sciencedirect.com/science/article/abs/pii/S1525505016306229
Social factors in marijuana use for medical and recreational purposes. (USA, abstract, 2017) https://www.epilepsybehavior.com/article/S1525-5050(16)30618-7/fulltext
Pharmacology of cannabinoids in the treatment of epilepsy. (USA, abstract, 2017) https://www.epilepsybehavior.com/article/S1525-5050(16)30579-0/fulltext
Social correlates of health status, quality of life, and mood states in patients treated with cannabidiol for epilepsy. (USA, abstract, 2017) https://www.sciencedirect.com/science/article/abs/pii/S1525505016307314
Cannabinoids therapeutic use: what is our current understanding following the introduction of THC, THC:CBD oromucosal spray and others? (Italy/ Spain/ Germany, abstract, 2017) https://pubmed.ncbi.nlm.nih.gov/28276775/
Cannabinoids as hippocampal network administrators. (USA, abstract, 2017) https://www.sciencedirect.com/science/article/abs/pii/S0028390817301405
Cannabidiol Treatment for Refractory Seizures in Sturge-Weber Syndrome. (USA, abstract, 2017) https://www.sciencedirect.com/science/article/abs/pii/S088789941730053X
Evaluation of Cannabidiol in Animal Seizure Models by the Epilepsy Therapy Screening Program (ETSP). (USA, abstract, 2017) https://link.springer.com/article/10.1007/s11064-017-2287-8
Altered responses of dopamine D3 receptor null mice to excitotoxic or anxiogenic stimuli: Possible involvement of the endocannabinoid and endovanilloid systems. (Italy, abstract, 2017) https://www.semanticscholar.org/paper/Altered-responses-of-dopamine-D3-receptor-null-mice-Micale-Cristino/e33564365e31533850f991a2fcd0dc95e54bb8b6
The potential role of cannabinoids in epilepsy treatment. (Italy, abstract, 2017) https://pubmed.ncbi.nlm.nih.gov/28845714/
Simple and fast gas-chromatography mass spectrometry assay to assess delta 9- tetrahydrocannabinol and cannabidiol in dogs treated with medical cannabis for canine epilepsy. (Italy, abstract, 2017) https://www.eurekaselect.com/157592/article
Efficacy and safety of cannabis for treating children with refractory epilepsy. (UK, abstract, 2017) https://pubmed.ncbi.nlm.nih.gov/29115760/
2016
FDA and Marijuana: Questions and Answers (article–2016) http://www.fda.gov/NewsEvents/PublicHealthFocus/ucm421168.htm
Using Medical Marijuana to Stop Childhood Seizures (news & abstract–2016) http://neurosciencenews.com/thc-cbd-childhood-seizures-3618/
Can Cannabis Treat Epileptic Seizures? (news–2016) http://www.scientificamerican.com/article/can-cannabis-treat-epileptic-seizures/
Buffington: I’m Growing Marijuana (news–2016) http://www.barrowjournal.com/archives/10490-BUFFINGTON-Im-growing-marijuana.html
Buffington: Medical Marijuana, Part 2 (news–2016) http://www.barrowjournal.com/archives/10515-BUFFINGTON-Medical-marijuana,-part-2.html
Preliminary Results of Uab’s Cbd Oil Studies Show Promise (news–2016) http://www.newswise.com/articles/view/649217/?sc=rsmn
Research Team Finds How CBD, a Component in Marijuana, Works Within Cells (news–2016) http://www.newswise.com/articles/view/629638/
Father advocates for exemption to pot ordinance to treat son’s severe epilepsy (news–2016) http://www.theunion.com/news/localnews/20665929-113/father-advocates-for-exemption-to-pot-ordinance-to
‘No-Buzz’ Medical Pot Laws Prove Problematic for Patients, Lawmakers (news–2016) http://www.nbcnews.com/storyline/legal-pot/no-buzz-medical-pot-laws-prove-problematic-patientslawmakers-n556196
Marijuana butter eased her child’s symptoms. Then her kids were taken away from her (news–2016) http://www.star-telegram.com/news/nation-world/national/article110342262.html
Minnesota doctor pushing the notion of cannabis for canines (news–2016) http://www.gosanangelo.com/story/life/wellness/2016/11/12/minnesota-doctor-pushing-notion-cannabiscanines/93748668/
Veterans Meet in Austin to Demand Passage of an All-Inclusive Medical Marijuana Policy in Texas (news–2016) http://www.dallasobserver.com/news/veterans-meet-in-austin-to-demand-passage-of-an-all-inclusivemedical-marijuana-policy-in-texas-8902310
Health care refugees: Medical marijuana and new hope (news–2016) http://www.cnn.com/2016/11/28/health/health-care-refugees-part-2/
Marijuana derivative CBD may help with hard-to-treat epilepsy (news–2016) http://www.upi.com/Health_News/2016/12/06/Marijuana-derivative-CBD-may-help-with-hard-to-treat-epilepsy/2141481059229/?spt=slh&or=10
CBD, Now A Schedule 1 Drug (news–2016) https://steemit.com/life/@gavicrane/cbd-schedual-1-drug
Doctored marijuana gives relief to boy whose parents found no other way to help him (news–2016) http://www.courant.com/health/hc-wapo-medial-marijuana-20170103-story.html
The Pharmacological Basis of Cannabis Therapy for Epilepsy. (USA, full, 2016) https://jpet.aspetjournals.org/content/357/1/45.long
Cannabinoids for pediatric epilepsy? Up in smoke or real science? (USA, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729003/
Transient increase of interleukin-1β after prolonged febrile seizures promotes adult epileptogenesis through long-lasting upregulating endocannabinoid signaling. (China/ Canada, full, 2016) https://www.nature.com/articles/srep21931
Analysis of endocannabinoid signaling elements and related proteins in lymphocytes of patients with Dravet syndrome. (Spain/ Italy, full, 2016) https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1002/prp2.220
ABC transporters P-gp and Bcrp do not limit the brain uptake of the novel antipsychotic and anticonvulsant drug cannabidiol in mice. (Australia, full, 2016) https://peerj.com/articles/2081/
CBD-enriched medical cannabis for intractable pediatric epilepsy: The current Israeli experience. (Israel, full, 2016) https://www.seizure-journal.com/article/S1059-1311(16)00005-4/fulltext
Case Series of Synthetic Cannabinoid Intoxication from One Toxicology Center. (USA, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899060/
Investigational new drugs for focal epilepsy. (UK, full, 2016) https://www.tandfonline.com/doi/full/10.1517/13543784.2016.1110144
Is the medical use of cannabis a therapeutic option for children? (Canada, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758425/
Endocannabinoid control of glutamate NMDA receptors: the therapeutic potential and consequences of dysfunction. (Spain, full, 2016) https://www.oncotarget.com/article/10095/
Dentate cannabinoid-sensitive interneurons undergo unique and selective strengthening of mutual synaptic inhibition in experimental epilepsy. (USA/ China, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785070/
Crucial Roles of the Endocannabinoid 2-Arachidonoylglycerol in the Suppression of Epileptic Seizures. (Japan, full, 2016) https://www.cell.com/cell-reports/fulltext/S2211-1247(16)30852-X
Turning Up the Heat on Endocannabinoid Signaling. (USA, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106110/
Δ9-THC Intoxication by Cannabidiol-Enriched Cannabis Extract in Two Children with Refractory Epilepsy: Full Remission after Switching to Purified Cannabidiol. (Brazil/ Italy, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043219/
Medical Marijuana for Epilepsy? (USA, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911937/
Aberrant epilepsy-associated mutant Nav1.6 sodium channel activity can be targeted with cannabidiol. (USA, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958898/
Anticonvulsant activity of β-caryophyllene against pentylenetetrazol-induced seizures. (Brazil, full, 2016) https://www.epilepsybehavior.com/article/S1525-5050(15)00695-2/fulltext
From cannabis to cannabidiol to treat epilepsy, where are we? (Italy/ UK, link to PDF, 2016) https://www.researchgate.net/publication/307592827_From_Cannabis_to_Cannabidiol_to_Treat_Epilepsy_Where_Are_We
Current Status and Prospects for Cannabidiol Preparations as New Therapeutic Agents. (USA, download, 2016) https://www.semanticscholar.org/paper/Current-Status-and-Prospects-for-Cannabidiol-as-New-Fasinu-Phillips/f079326032ec0e932601466d7beb81bc191baa67?p2df
Pharmacokinetic-pharmacodynamic influence of N-palmitoylethanolamine, arachidonyl2′-chloroethylamide and WIN 55,212-2 on the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice. (Italy, click “coreacuk” for download, 2016) https://www.sciencedirect.com/science/article/abs/pii/S0014299916306161
Effects of Marijuana on ictal and interictal EEG activity in idiopathic generalized epilepsy. (USA, click “semanticscholar” for download, 2016) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Effects+of+Marijuana+on+ictal+and+interictal+EEG+activity+in+idiopathic+generalized+epilepsy.+++%22&btnG
Cannabidiol Post-Treatment Alleviates Rat Epileptic-Related Behaviors and Activates Hippocampal Cell Autophagy Pathway Along with Antioxidant Defense in Chronic Phase of Pilocarpine-Induced Seizure. (Iran, Abstract, 2016) https://link.springer.com/article/10.1007/s12031-015-0703-6
Cannabis and epilepsy: An ancient treatment returns to the fore. (USA, Abstract, 2016) https://pubmed.ncbi.nlm.nih.gov/27989385/
Synthetic cannabinoids revealing adrenoleukodystrophy. (Israel, Case report, 2016) https://www.sciencedirect.com/science/article/abs/pii/S0967586815004567
Adverse effects after the use of JWH-210 - a case series from the EU Spice II plus project. (Germany, case reports, 2016) https://www.semanticscholar.org/paper/Adverse-effects-after-the-use-of-JWH-210-a-case-the-Hermanns-Clausen-Kithinji/7f72a2b975a3b9ff5c94c83c951d24cd69574361
Plant-Derived and Endogenous Cannabinoids in Epilepsy. (Italy, abstract, 2016) https://link.springer.com/article/10.1007/s40261-016-0379-x
Involvement of TRPV1 channels in the activity of the cannabinoid WIN 55,212-2 in an acute rat model of temporal lobe epilepsy. (Italy, abstract, 2016) https://www.sciencedirect.com/science/article/abs/pii/S092012111630016X
Cannabidiol and epilepsy: rationale and therapeutic potential. (Italy, abstract, 2016) https://www.sciencedirect.com/science/article/abs/pii/S1043661816301797
The cannabinoid receptor agonist WIN55.212 reduces consequences of status epilepticus in rats. (Russia/ Netherlands, abstract, 2016) https://www.sciencedirect.com/science/article/abs/pii/S0306452216303670
Marijuana use in adults admitted to a Canadian epilepsy monitoring unit. (Canada, abstract, 2016) https://www.epilepsybehavior.com/article/S1525-5050(16)30334-1/fulltext
Endogenous cannabinoid system alterations and their role in epileptogenesis after brain injury in rat. (China, abstract, 2016) https://www.sciencedirect.com/science/article/abs/pii/S0920121116302406?via%3Dihub
Targeting brain and peripheral plasticity of the lipidome in acute kainic acid-induced epileptic seizures in mice via quantitative mass spectrometry. (Germany, abstract, 2016) https://www.sciencedirect.com/science/article/abs/pii/S1388198116303092
2015
Cannabis, Medical Science, and Fundamental Human Rights, With Dr. Ethan Russo (article–2015) http://www.huffingtonpost.com/sunil-kumar-aggarwal/cannabis-science-and-fund_b_8334384.html
Medical Marijuana Liquid Could Help Treat Severe Epilepsy in Children (news – 2015) http://neurosciencenews.com/cannabidiol-epilepsy-neuropharmacology-1949/
How Medical Marijuana’s Chemicals May Protect Cells (news–2015) http://www.scientificamerican.com/article/how-medical-marijuana-s-chemicals-may-protect-cells/
Many States Mulling Medical Marijuana Bills (news–2015) http://www.webmd.com/mental-health/news/20150212/states-medical-marijuana-legislation
Oshawa woman says marijuana helped curb her constant seizures (news–2015) http://toronto.ctvnews.ca/oshawa-woman-says-marijuana-helped-curb-her-constant-seizures-1.2246708
What ailments does medical marijuana help? (news–2015) http://www.mnn.com/health/fitness-well-being/stories/what-ailments-does-medical-marijuana-help
The Science Behind Sanjay Gupta’s WEED 3 (news–2015) http://blog.sfgate.com/smellthetruth/2015/04/21/the-science-behind-sanjay-guptas-weed-3/
Big Pharma-Produced Cannabis Is Likely Coming to the US (news–2015) http://www.huffingtonpost.com/alice-oleary-randall/medical-cannabis-issue-th_b_7925956.html
Study confirms safety of cannabis drug CBD (news–2015) https://www.epilepsy.org.uk/news/news/study-confirms-safety-cannabis-drug-cbd-64709
Could Marijuana Chemical Help Ease Epilepsy? (news–2015) http://www.webmd.com/epilepsy/news/20150909/could-marijuana-chemical-help-ease-epilepsy
Why THC Isn’t The Only Thing In Weed That Matters (news–2015) http://www.refinery29.com/2015/08/92201/cbd-medical-marijuana-facts#.d3jbvn:v7pE
Could medical marijuana help your dog? (news–2015) http://www.katu.com/news/local/Could-medical-marijuana-help-your-dog-347304162.html
‘Grandma’s magic remedy:’ Mexico’s medical marijuana secret (news–2015) https://www.yahoo.com/news/grandmas-magic-remedy-mexicos-medical-marijuana-secret-071008150.html?ref=gs
New Minnesota marijuana strain more potent, could cut costs (news–2015) http://www.twincities.com/2015/12/15/new-minnesota-marijuana-strain-more-potent-could-cut-costs/
Pharmaceutical CBD (cannabidiol) Shows Promise for Children with Severe Epilepsy (news–2015) https://www.aesnet.org/about_aes/press_releases/pharmaceuticalcbd2015#sthash.wL57kCVn.dpuf
Special Report: Georgia’s medical marijuana treatment trials underway (news–2015) http://www.41nbc.com/2015/02/05/special-report-georgias-medical-marijuana-treatment-trials-underway/
Marijuana Derivative Reduces Seizures in People With Treatment Resistant Epilepsy (news–2015) https://www.sciencedaily.com/releases/2015/12/151223221532.htm
The Outsourcing of American Marijuana Research (news–2015) http://www.newsweek.com/2015/12/25/outsourcing-american-marijuana-research-406184.html
Medical marijuana improves quality of life for S.J. family (news–2015) http://www.phillyvoice.com/medical-marijuana-improves-quality-of-life-for-one-sj-family/
Hemp Oil Giving Iowa Woman Her Life Back (news–2015) http://whotv.com/2015/02/09/hemp-oil-giving-iowa-woman-her-life-back/
Perth mum uses hemp oil medicinal cannabis to treat daughter with rare disease (news–2015) http://www.news.com.au/lifestyle/health/health-problems/perth-mum-uses-hemp-oil-medicinal-cannabis-to-treat-daughter-with-rare-disease/news-story/e8080f71e7316bc2dcc64cbc4fcd5fd3
Augmented Inhibition from Cannabinoid-Sensitive Interneurons Diminishes CA1 Output after Traumatic Brain Injury. (USA, full, 2015) https://www.frontiersin.org/articles/10.3389/fncel.2014.00435/full
Muscarinic M1 receptor and cannabinoid CB1 receptor do not modulate paraoxoninduced seizures. (USA, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317231/
Medicinal cannabis. (Australia, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674028/
Cannabidiol Rescues Acute Hepatic Toxicity and Seizure Induced by Cocaine. (Brazil, full, 2015) https://www.hindawi.com/journals/mi/2015/523418/
Defects in fatty acid amide hydrolase 2 in a male with neurologic and psychiatric symptoms. (Canada/ USA, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423390/
Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents. (USA, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284516/
Interaction between Cannabinoid Compounds and Capsazepine in Protection against Acute Pentylenetetrazole-induced Seizure in Mice. (Iran, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499434/
Phytocannabinoids and epilepsy. (Brazil, full, 2015) https://onlinelibrary.wiley.com/doi/full/10.1111/jcpt.12235
Cannabinoids and Epilepsy. (Brazil, full, 2015) https://link.springer.com/article/10.1007/s13311-015-0375-5
Impaired 2-AG signaling in hippocampal glutamatergic neurons: aggravation of anxiety-like behavior and unaltered seizure susceptibility. (Germany/ Australia, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772822/
Cannabinoids: is there a potential treatment role in epilepsy? (USA, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845642/
Loss of Either Rac1 or Rac3 GTPase Differentially Affects the Behavior of Mutant Mice and the Development of Functional GABAergic Networks. (Italy, full, 2015) https://academic.oup.com/cercor/article/26/2/873/2367254
TRPV1 Channel: A Potential Drug Target for Treating Epilepsy. (Turkey, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598436/
Narrative review of the safety and efficacy of marijuana for the treatment of commonly state-approved medical and psychiatric disorders. (USA, full, 2015) https://ascpjournal.biomedcentral.com/articles/10.1186/s13722-015-0032-7
Homer Protein-Metabotropic Glutamate Receptor Binding Regulates Endocannabinoid Signaling and Affects Hyperexcitability in a Mouse Model of Fragile X Syndrome. (USA, full, 2015) https://www.jneurosci.org/content/35/9/3938.long
Enhancement of endocannabinoid signalling protects against cocaine-induced neurotoxicity. (Brazil, full, 2015) https://www.sciencedirect.com/science/article/pii/S0041008X15001556
Drug-drug interaction between clobazam and cannabidiol in children with refractory epilepsy. (USA, full, 2015) https://onlinelibrary.wiley.com/doi/full/10.1111/epi.13060
Marijuana: A Time-Honored but Untested Treatment for Epilepsy. (Canada, full, 2015) https://www.cambridge.org/core/journals/canadian-journal-of-neurological-sciences/article/div-classtitlemarijuana-a-time-honored-but-untested-treatment-for-epilepsydiv/DDEDDD9EAA09918D3D69CC7CA047AE5C
Molecular Targets of Cannabidiol in Neurological Disorders. (UK, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604182/
The basolateral amygdala γ-aminobutyric acidergic system in health and disease. (USA, full, 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837071/
Cannabinoid and nitric oxide signaling interplay in the modulation of hippocampal hyperexcitability: Study on electrophysiological and behavioral models of temporal lobe epilepsy in the rat. (Italy, full, 2015) https://www.academia.edu/17120812/Cannabinoid_and_nitric_oxide_signaling_interplay_in_the_modulation_of_hippocampal_hyperexcitability_Study_on_electrophysiological_and_behavioral_models_of_temporal_lobe_epilepsy_in_the_rat
ACEA (a highly selective cannabinoid CB1 receptor agonist) stimulates hippocampal neurogenesis in mice treated with antiepileptic drugs. (Poland, full, 2015) https://www.academia.edu/23685614/ACEA_a_highly_selective_cannabinoid_CB1_receptor_agonist_stimulates_hippocampal_neurogenesis_in_mice_treated_with_antiepileptic_drugs
The effects of adolescent cannabinoid exposure on seizure susceptibility and lethality in adult male rats. (USA, full, 2015) https://www.academia.edu/20941362/The_effects_of_adolescent_cannabinoid_exposure_on_seizure_susceptibility_and_lethality_in_adult_male_rats
Options for pharmacoresistant epilepsy in children: when medications don't work. (USA, link to PDF, 2015) https://www.researchgate.net/publication/272077097_Options_for_Pharmacoresistant_Epilepsy_in_Children_When_Medications_Don%27t_Work
Marijuana Use in Epilepsy: The Myth and the Reality. (USA, link to PDF, 2015) https://www.researchgate.net/publication/281486167_Marijuana_Use_in_Epilepsy_The_Myth_and_the_Reality
Cannabidiol as potential treatment in refractory pediatric epilepsy. (Italy, link to PDF, 2015) https://www.researchgate.net/publication/283903203_Cannabidiol_as_potential_treatment_in_refractory_pediatric_epilepsy
The role of cannabinoids and leptin in neurological diseases. (Turkey, link to PDF, 2015) https://www.researchgate.net/publication/287360490_The_role_of_cannabinoids_and_endocannabinoid_system_in_the_treatment_of_epilepsy
Pure cannabidiol in the treatment of malignant migrating partial seizures in infancy: a case report. (USA, download, 2015) http://www.orvosikannabisz.com/wp-content/uploads/2016/12/Pure-Cannabidiol-in-the-Treatment-of-Malignant-Migrating-Partial-Seizures-in-Infancy-A-Case-Report-Saade2015-2.pdf
Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial. (USA, link to abstract, 2015) https://www.sciencedirect.com/science/article/abs/pii/S1474442215003798
Perceived efficacy of cannabidiol-enriched cannabis extracts for treatment of pediatric epilepsy: A potential role for infantile spasms and Lennox-Gastaut syndrome. (USA, link to abstract, 2015) https://www.sciencedirect.com/science/article/abs/pii/S1525505015001572
Palmitoylethanolamide attenuates PTZ-induced seizures through CB1 and CB2 receptors. (Iran, Link to Abstract, 2015) https://www.sciencedirect.com/science/article/abs/pii/S0920121115300401
Changes over time of cannabinoid receptor 1 in hippocampus of status epilepticus rats. (China, abstract, 2015) https://pubmed.ncbi.nlm.nih.gov/26168676/
Attenuation of kainic acid-induced status epilepticus by inhibition of endocannabinoid transport and degradation in guinea pigs. (Russia, abstract, 2015) https://www.sciencedirect.com/science/article/abs/pii/S0920121115000133
Neuroprotective effects of trans-caryophyllene against kainic Acid induced seizure activity and oxidative stress in mice. (China, abstract, 2015) https://www.semanticscholar.org/paper/Neuroprotective-Effects-of-Trans-Caryophyllene-Acid-Liu-Song/f8ce9bcb572371a7e107776e958023208adb187e
Effects of WIN 55,212-2 (a synthetic cannabinoid CB1 and CB2 receptor agonist) on the anticonvulsant activity of various novel antiepileptic drugs against 6 Hz-induced psychomotor seizures in mice. (Poland, abstract, 2015) https://www.sciencedirect.com/science/article/abs/pii/S0091305715000052
Inhibition of monoacylglycerol lipase mediates a cannabinoid 1-receptor dependent delay of kindling progression in mice. (Germany, abstract, 2015) https://www.sciencedirect.com/science/article/abs/pii/S0969996115000881
Withdrawal Seizures Seen In the Setting of Synthetic Cannabinoid Abuse. (USA, abstract, 2015) https://www.ajemjournal.com/article/S0735-6757%2815%2900169-2/fulltext
Parental reporting of response to oral cannabis extracts for treatment of refractory epilepsy. (USA, abstract, 2015) https://www.epilepsybehavior.com/article/S1525-5050(15)00104-3/fulltext
Influence of arachidonyl-2'-chloroethylamide, a selective cannabinoid CB1 receptor agonist, on the anticonvulsant and acute side-effect potentials of clobazam, lacosamide and pregabalin in the maximal electroshock-induced seizure model and chimney test in mice. (Poland, abstract, 2015) https://www.semanticscholar.org/paper/Influence-of-arachidonyl%E2%80%902%E2%80%B2%E2%80%90chloroethylamide%2C-a-CB1-Florek-Luszczki-Zagaja/9afc69aba34a5995f8fc835b1b6a2808127c18f1
Long-term disease-modifying effect of the endocannabinoid agonist WIN55,212-2 in a rat model of audiogenic epilepsy. (Russia/ Netherlands, abstract, 2015) https://www.sciencedirect.com/science/article/abs/pii/S1734114014003739?via%3Dihub
JWH-018 impairs sensorimotor functions in mice. (Italy, abstract, 2015) https://www.sciencedirect.com/science/article/abs/pii/S0306452215004534
Cannabidiol, a Cannabis sativa constituent, inhibits cocaine-induced seizures in mice: Possible role of the mTOR pathway and reduction in glutamate release. (Brazil, abstract, 2015) https://www.sciencedirect.com/science/article/abs/pii/S0161813X15001229
Cannabis and Endocannabinoid Signaling in Epilepsy. (Hungary, abstract, 2015) https://link.springer.com/chapter/10.1007%2F978-3-319-20825-1_10
Convulsant effects of high efficacy synthetic cannabinoid JWH-018 in mice. (USA, abstract, 2015) https://faseb.onlinelibrary.wiley.com/doi/10.1096/fasebj.29.1_supplement.614.7
The cannabinoid CB2 receptor-specific agonist AM1241 increases pentylenetetrazoleinduced seizure severity in Wistar rats. (Brazil/ USA, abstract, 2015) https://www.sciencedirect.com/science/article/abs/pii/S0920121116301310
2014
Physicians, Medical Marijuana, and the Law (article–2014) http://journalofethics.ama-assn.org/2014/09/hlaw1-1409.html
The Comprehensive Report on the Cannabis Extract Movement and the Use of Cannabis
Extracts to Treat Diseases (link to upload-2014) http://www.slideshare.net/TheHempSolution/comprehensive-report-on-the-cannabis-extract-movement
Medical Marijuana in the UK: As a doctor, should I be able to prescribe cannabis to my patients? (article–2014) http://www.independent.co.uk/voices/medical-marijuana-in-the-uk-as-a-doctor-should-i-be-able-to-prescribe-cannabis-to-my-patients-9791583.html
An Ingredient of Pot May Help People with Epilepsy (news-2014) http://www.scientificamerican.com/article/an-ingredient-of-pot-may-help-people-with-epilepsy/
Federal red tape ties up marijuana research (news-2014) http://www.nature.com/news/federal-red-tape-ties-up-marijuana-research-1.14926
This Family Had To Fire Their Doctor To Get Medical Marijuana For Their Son (news–2014) http://www.huffingtonpost.com/2014/03/25/epilepsy-medical-marijuana_n_5022008.html
Marijuana tested as treatment for children with epilepsy (news–2014) http://www.sfgate.com/health/article/Marijuana-tested-as-treatment-for-children-with-5246372.php?cmpid=twitter-mobile
Federal marijuana bill would legalize some cannabis strains (news–2014) http://www.cnn.com/2014/07/28/health/federal-marijuana-bill/index.html
Why CBD Is Not Enough: The Entourage Effect (news–2014) https://www.massroots.com/learn/what-is-cannabis-entourage-effect
Desperate Journey (news–2014) http://extras.denverpost.com/stateofhope/
Marijuana research hampered by access from government and politics, scientists say (news–2014) http://www.washingtonpost.com/national/health-science/marijuana-research-hampered-by-access-fromgovernment-and-politics-scientists-say/2014/03/21/6065eb88-a47d-11e3-84d4-e59b1709222c_story.html
The new faces of marijuana (news–2014) http://www.msnbc.com/hardball/the-new-faces-marijuana
A cannabis-based drug is showing ‘promise’ in children with severe epilepsy (news–2014) http://www.telegraph.co.uk/finance/newsbysector/pharmaceuticalsandchemicals/11161610/A-cannabis-based-drug-is-showing-promise-in-children-with-severe-epilepsy.html
2013
Medical Marijuana Coverage Still Lost in the Legal Weeds (article–2013) https://www.managedcaremag.com/archives/2013/1/medical-marijuana-coverage-still-lost-legal-weeds
New cannabis discovery could lead to better treatments for epilepsy (news–2013) http://www.reading.ac.uk/news-and-events/releases/PR464765.aspx
Medical Marijuana for Kids? Some Praise Results While Others Worry About Risks (news–2013) http://www.cnbc.com/id/100876423
New therapy for fragile X chromosome syndrome discovered (news–2013) https://www.sciencedaily.com/releases/2013/04/130410082413.htm
Toronto family hopes for access to controversial treatment to cure baby’s rare epilepsy (news–2013) http://globalnews.ca/news/714104/toronto-family-hopes-for-access-to-controversial-treatment-to-curebabys-rare-epilepsy/
THC Can Prevent Brain Damage – Study (news–2013) http://www.science20.com/news_articles/thc_can_prevent_brain_damage_study-113512
Families of children with epilepsy moving to Colorado, drawn by success of marijuana oil (news–2013) http://gazette.com/families-of-children-with-epilepsy-moving-to-colorado-drawn-by-success-of-marijuanaoil/article/1507895#AZpGzkjtp6Hzx785.99
Families migrate to Colorado for marijuana miracle (news–2013) http://archive.sltrib.com/story.php?ref=/sltrib/news/57052556-78/piper-annie-seizures-cbd.html.csp
Comes Now Epidiolex (FDA approves IND studies of CBD) (news–2013) http://www.beyondthc.com/comes-now-epidiolex-fda-approves-ind-studies-of-cbd/
Cannabis-Based Epilepsy Drug Approved For Clinical Trials (news–2013) http://www.medicaljane.com/2013/10/23/cannabis-based-epilepsy-drug-approved-for-clinical-trials/
New Research Finds Marijuana May Combat Brain Damage (news–2013) http://thejointblog.com/new-research-finds-marijuana-may-combat-brain-damage/
2012
Science/UK: Antiepileptic efficacy of cannabidivarin will be tested in clinical studies (news–2012) http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=382
‘Hammer Head’ ‘incense’ blamed for seizure of youth in Le Roy (news–2012) http://thebatavian.com/howard-owens/hammer-head-incense-blamed-seizure-youth-le-roy/29983
2011
Pot Compound Exerts Anticonvulsant Effects In Animal Models Of Epilepsy (news-2011) http://norml.org/news/2011/01/20/pot-compound-exerts-anticonvulsant-effects-in-animal-models-of-epilepsy
New research provides hope for those with epilepsy (news-2011) http://medicalxpress.com/news/2011-04-epilepsy.html
2010
Marijuana, autism, and failure: a true story (news–2010) http://www.alexneedshelp.com/marijuana-autism-and-failure-a-true-story#.VOBDOC74Y5w