LIVER DISEASE - NON HEPATITIS - LIVER FUNCTIONS

LIVER DISEASE - NON HEPATITIS - LIVER FUNCTIONS:

• Marijuana use is inversely associated with liver steatosis detected by transient elastography in the general United States population in NHANES 2017-2018: A cross sectional study.  https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0284859 
• IS CBD TOXIC TO THE LIVER?:  https://www.projectcbd.org/science/cbd-toxic-liver?utm_source=Project+CBD+Mailing+List&utm_campaign=fc2e6f0c39-EMAIL_CAMPAIGN_2020_02_26_07_50_COPY_01&utm_medium=email&utm_term=0_ea5031784e-fc2e6f0c39-11562609
• Potential Mechanisms Influencing the Inverse Relationship between Cannabis and Nonalcoholic Fatty Liver Disease: A Commentary. (NIH-2019)   https://www.ncbi.nlm.nih.gov/pubmed/31308686
• Cannabis Use is associated with Reduced prevalence of Non-alcoholic Fatty Liver Disease: A Cross Sectional Study. (NIH 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404771/

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• 2020
• Involvement of endocannabinoid system, inflammation and apoptosis in diabetes induced liver injury: Role of 5-HT3 receptor antagonist. (Iran, abstract, 2020) https://www.sciencedirect.com/science/article/pii/S1567576919322684 
• 2019
• Cannabinoid-2 receptor activation ameliorates hepatorenal syndrome. (USA, abstract, 2019) https://pubmed.ncbi.nlm.nih.gov/31770583/ 
• Cannabis consumption and non-alcoholic fatty liver disease. A three years longitudinal study in first episode non-affective psychosis patients. (Spain, abstract, 2019) https://www.sciencedirect.com/science/article/abs/pii/S0278584619301393 
• Marijuana Consumption in Liver Transplant Recipients. (USA, abstract, 2019) https://www.semanticscholar.org/paper/Marijuana-Consumption-in-Liver-Transplant-Rodriguez-Strassle/16fc02dd608ab5fe2347209b98f030e8cd3352ab 
• No influence of cannabis use on liver stiffness in HIV-HCV co-infected patients (ANRS CO13 HEPAVIH cohort study). (France, 1st page, 2019) https://journals.lww.com/eurojgh/Citation/2019/02000/No_influence_of_cannabis_use_on_liver_stiffness_in.21.aspx 
• Endocannabinoid Signalling in Atherosclerosis and Related Metabolic Complications. (Germany, 1st page, 2019) https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0039-1678738 
• Endocannabinoid System in Hepatic Glucose Metabolism, Fatty Liver Disease, and Cirrhosis. (Germany, full, 2019) https://www.mdpi.com/1422-0067/20/10/2516/htm 
• Countering the Modern Metabolic Disease Rampage With Ancestral Endocannabinoid System Alignment. (USA, full, 2019) https://www.frontiersin.org/articles/10.3389/fendo.2019.00311/full 
• Potential Mechanisms Influencing the Inverse Relationship Between Cannabis and Nonalcoholic Fatty Liver Disease: A Commentary. (USA, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612909/ 
• Canadian Association of Gastroenterology Position Statement: Use of Cannabis in Gastroenterological and Hepatic Disorders. (Canada/ Germany, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507278/ 
• FABP1 controls hepatic transport and biotransformation of Δ9-THC. (USA, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527858/ 
• Therapeutic Prospects of Cannabidiol for Alcohol Use Disorder and Alcohol-Related Damages on the Liver and the Brain. (France/ Belgium, full, 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554654/ 
• Cannabis: From a Plant That Modulates Feeding Behaviors toward Developing Selective Inhibitors of the Peripheral Endocannabinoid System for the Treatment of Obesity and Metabolic Syndrome. (Israel, full, 2019) https://www.mdpi.com/2072-6651/11/5/275/htm 
• Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration. (USA, full, 2019) https://www.mdpi.com/1420-3049/24/12/2256/htm 
• That Alarming CBD Liver Damage Study Is Bunk—And the Media Should Know Better  (news–2019) https://www.leafly.com/news/industry/alarming-cbd-liver-damage-study-is-bunk

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• 2018
• Cannabis in liver disorders: a friend or a foe? (USA, abstract, 2018) https://www.semanticscholar.org/paper/Cannabis-in-liver-disorders%3A-a-friend-or-a-foe-Goyal-Rahman/f8827bc7727c62c63e688a5852ac7a39a2e6775f 
• Human Liver Fatty Acid Binding Protein-1 T94A Variant, Non-alcohol Fatty Liver Disease, and Hepatic Endocannabinoid System. (USA, abstract, 2018) https://pubmed.ncbi.nlm.nih.gov/29488637/ 
• Long-Term Heavy Recreational Cannabis Use and Serum Delta-9-Tetrahydrocannabinol Levels are not Associated with an Impaired Liver Function in Cannabis Dependents. (Germany, PDF, 2018) https://www.researchgate.net/publication/326665079_Long-Term_Heavy_Recreational_Cannabis_Use_and_Serum_Delta-9-Tetrahydrocannabinol_Levels_are_not_Associated_with_an_Impaired_Liver_Function_in_Cannabis_Dependents 
• Cannabis use is associated with reduced prevalence of progressive stages of alcoholic liver disease. (USA/ Canada, PDF, 2018) https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0176416 
• Marijuana is not associated with progression of hepatic fibrosis in liver disease: a systematic review and meta-analysis. (USA, PDF, 2018) https://www.researchgate.net/publication/327798677_Marijuana_is_not_associated_with_progression_of_hepatic_fibrosis_in_liver_disease_a_systematic_review_and_meta-analysis 
• GPR55 deficiency is associated with increased adiposity and impaired insulin signaling in peripheral metabolic tissues. (UK, full, 2018) https://faseb.onlinelibrary.wiley.com/doi/10.1096/fj.201800171R 
• Cannabinoids and reduced risk of hepatic steatosis in HIV-HCV co-infection: paving the way for future clinical research. (France, full, 2018) https://www.tandfonline.com/doi/full/10.1080/14787210.2018.1473764 
• Reduced Incidence and Better Liver Disease Outcomes among Chronic HCV Infected Patients Who Consume Cannabis. (USA/ Canada, full, 2018) https://www.hindawi.com/journals/cjgh/2018/9430953/ 
• Maternal high-fat diet consumption induces sex-dependent alterations of the endocannabinoid system and redox homeostasis in liver of adult rat offspring. (Brazil, full, 2018) https://www.nature.com/articles/s41598-018-32906-0 
• The Role of Cannabinoids in the Setting of Cirrhosis. (USA, full, 2018) https://www.mdpi.com/2305-6320/5/2/52/htm 
• Irinotecan and Δ⁸-Tetrahydrocannabinol Interactions in Rat Liver: A Preliminary Evaluation Using Biochemical and Genotoxicity Markers. (Croatia, full, 2018) https://www.mdpi.com/1420-3049/23/6/1332/htm 
• Mechanistic Potential and Therapeutic Implications of Cannabinoids in Nonalcoholic Fatty Liver Disease. (USA, full, 2018) https://www.mdpi.com/2305-6320/5/2/47/htm  
• Study Shows Cannabis Protects the Liver From Alcohol Damage. (news – 2018)
  https://www.leafly.com/news/health/cannabis-and-alcoholic-liver-disease

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• 2017
• Non-clinical toxicity of β-caryophyllene, a dietary cannabinoid: Absence of adverse effects in female Swiss mice. (Brazil, abstract, 2017) https://www.sciencedirect.com/science/article/abs/pii/S0273230017304014?via%3Dihub 
• Re-visiting the Endocannabinoid System and Its Therapeutic Potential in Obesity and Associated Diseases. (USA, abstract, 2017) https://link.springer.com/article/10.1007%2Fs11892-017-0924-x 
• CB-1R and GLP-1R gene expressions and oxidative stress in the liver of diabetic rats treated with sitagliptin. (Turkey, abstract, 2017) https://link.springer.com/article/10.1016/j.pharep.2017.03.013 
• Effect of cannabinoid receptor-2 agonist AM1241 on platelet-derived growth factor expression in the liver tissue of mice with hepatic fibrosis. (China, abstract, 2017) https://www.researchgate.net/publication/322475636_Effect_of_cannabinoid_receptor-2_agonist_AM1241_on_platelet-derived_growth_factor_expression_in_the_liver_tissue_of_mice_with_hepatic_fibrosis 
• Loss of fatty acid binding protein-1 alters the hepatic endocannabinoid system response to a high fat diet. (USA, full, 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665667/ 
• Cannabis use is associated with reduced prevalence of non-alcoholic fatty liver disease: A cross-sectional study. (USA/ Canada, full, 2017) https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0176416 
• Daytime-Dependent Changes of Cannabinoid Receptor Type 1 and Type 2 Expression in Rat Liver. (Germany, full, 2017) https://www.mdpi.com/1422-0067/18/9/1844/htm 
• Marijuana And Fatty Liver Disease: How The Plant Can Help (news–2017) https://thefreshtoast.com/cannabis/a-fat-joint-for-a-fat-liver-may-be-what-the-doctor-ordered/
• Weed Power: Milk Thistle, Liver Disease and the Endocannabinoid System (news–2017) http://www.alternet.org/drugs/weed-power-milk-thistle-liver-disease-endocannaboid-system
• 2016
• FABP1: A Novel Hepatic Endocannabinoid and Cannabinoid Binding Protein. (USA, abstract, 2016) https://pubs.acs.org/doi/abs/10.1021/acs.biochem.6b00446 
• Crosstalk between liver antioxidant and the endocannabinoid systems after chronic administration of the FAAH inhibitor, URB597, to hypertensive rats. (Poland, abstract, 2016) https://www.sciencedirect.com/science/article/abs/pii/S0041008X1630076X 
• Cannabinoid Receptor 1 Mediates Homing of Bone Marrow-Derived Mesenchymal Stem Cells Triggered by Chronic Liver Injury. (China, abstract, 2016) https://www.semanticscholar.org/paper/Cannabinoid-Receptor-1-Mediates-Homing-of-Bone-Stem-Wang-Yang/e470d065d65391eca97432c2dbc71f4eba408b3e 
• Endocannabinoids signaling: Molecular mechanisms of liver regulation and diseases. (China, pdf, 2016) https://www.semanticscholar.org/paper/Endocannabinoids-signaling%3A-Molecular-mechanisms-of-Wang-Meng/049ef5dd3caf9dc4095b57b74ec9f1cb00aac865 
• Serum levels of endocannabinoids are independently associated with nonalcoholic fatty liver disease. (Israel, full, 2016) https://onlinelibrary.wiley.com/doi/full/10.1002/oby.21687 
• Cannabinoids, inflammation, and fibrosis. (USA, full, 2016) https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.201600646R 
• The Cannabinoid Receptor 2 Protects Against Alcoholic Liver Disease Via a Macrophage Autophagy-Dependent Pathway. (France, full, 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921859/ 
• 2015
• Two non-psychoactive cannabinoids reduce intra-cellular lipid levels and inhibit hepatosteatosis. (Italy/ UK, abstract, 2015) https://www.sciencedirect.com/science/article/abs/pii/S0168827815000033 
• Ultra Low Dose Delta 9-Tetrahydrocannabinol Protects Mouse Liver from Ischemia Reperfusion Injury. (Israel, full, 2015) https://www.karger.com/Article/FullText/430165 
• Cannabidiol Rescues Acute Hepatic Toxicity and Seizure Induced by Cocaine. (Brazil, full, 2015) https://www.hindawi.com/journals/mi/2015/523418/ 
• The prescription of medical cannabis by a transitional pain service to wean a patient with complex pain from opioid use following liver transplantation : a case report. (Canada, Full, 2015) https://link.springer.com/article/10.1007/s12630-015-0525-6  

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• 2014
• New Study: Cannabis May Protect Liver From Alcohol Related Damage (news–2014) https://thejointblog.com/new-study-cannabis-may-protect-liver-alcohol-related-damage/
• 2011
• Cannabis Compound Induces Death Of Cells Associated With Liver Fibrosis (news–2011) http://norml.org/news/2011/06/30/cannabis-compound-induces-death-of-cells-associated-with-liver-fibrosis

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