CANNABIDIOL (CBD)

Cannabidiol (CBD)

• Know properties with synergistic terpenes
  • Anti-inflammatory (Hampson et al., 1998)
    • Limonene et al
  • Anti-convulsant (Jones et al., 2010)
    • Linalool
  • Anti-oxidant (Hampson et al., 1998)
    • Limonene et al.
  • Anti-psychotic
  • Anti-anxiety via 5-HT1A (Russo et al., 2005)
    • Linalool
    • Limonene
  •  Cytotoxic versus breast cancer (Ligresti et al., 2006)
    • Limonene
  • Effective versus MRSA (Appendino et al., 2008)
    • Pinene
  • ↑ adenosine A2A signalling (Carrier et al., 2006)
    • Linalool
  •  Treatment of addiction
    • Caryophyllene
  • Decreases sebum/sebocytes (Biro et al., 2009)
    • Pinene
    • limonene
    • linalool
• 2023
• Cannabidiol as an adjunctive treatment for acute bipolar depression: A pilot study. https://pubmed.ncbi.nlm.nih.gov/37920963/ 
• Antihypertensive effects of CBD are mediated by altered inflammatory response: a sub-study of the Hyper-H21-4 trial. https://www.sciencedirect.com/science/article/pii/S1756464623004735? 
• Oral cannabidiol for prevention of chemotherapy-induced peripheral neuropathy. https://www.annalsofoncology.org/article/S0923-7534(23)01692-7/fulltext 
• Highly purified cannabidiol efficacy and safety in a cohort of adult patient with various types of drug-resistant epilepsies. https://pubmed.ncbi.nlm.nih.gov/37806886/ 
• Consumer perception, knowledge, and uses of Cannabidiol (CBD). https://meridian.allenpress.com/mhc/article/13/5/217/496172? 
• CBD as a cure-all? The impacts of state-level legalization of prescription cannabidiol on opioid prescriptions. https://onlinelibrary.wiley.com/doi/10.1002/soej.12667 
• Real life experience with purified cannabidiol treatment for refractory epilepsy: A multi-center retrospective study. https://www.pedneur.com/article/S0887-8994(23)00362-4/fulltext 
• Eight weeks of daily cannabidiol supplementation improves sleep quality and immune cell cytotoxicity. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574483/ 
• Effects of cannabidiol on metabolic modulation and improving sports performance: A systematic review. https://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/330
• Perceptions and opinions of Cannabidiol in the orthopedic and sports medicine community. https://journals.sagepub.com/doi/full/10.1177/23259671231191766 
• Effects of CBD on the physiology of Nile tilapia, (oreochromisn niloticus) as a chronic stress mitigating agent in vivo. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0290835 
• CBD safety profile: Real-world evidence study shows compelling results for full spectrum  CBD. https://www.endocannabinoidmedicine.com/news/cbd-safety-profile-real-world-evidence-study-shows-compelling-results-for-full-spectrum-cbd/ 
• The effects of cannabidiol on worry and anxiety among high trait worriers: a double-blind, randomized, placebo controlled trial. https://pubmed.ncbi.nlm.nih.gov/37552290/ 
• The effects of long-term self-dosing of cannabidiol on drowsiness, testosterone levels and liver function. https://pubmed.ncbi.nlm.nih.gov/36968131/
• Cannabidiol acts as a molecular switch in innate immune cells to promote the biosynthesis of inflammation-resolving lipid mediators. https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(23)00249-0 
• Cannabidiol's impact on drug metabolization.  https://pubmed.ncbi.nlm.nih.gov/37541924/ 
• Daily Cannabidiol Administration for 10 weeks modulates hippocampal and amygdalar resting-state functional connectivity in Cannabis users: A Functional Magnetic Resonance Imaging Open Label Clinical trial. https://www.liebertpub.com/doi/10.1089/can.2022.0336 
• A Systemic review of Cannabidiol trials in Neurodevelopmental disorders. https://pubmed.ncbi.nlm.nih.gov/37543051/ 
• Update on Cannabidiol Clinical toxicity and Adverse Effects: A systematic Review. https://www.eurekaselect.com/article/130324 
• Cannabidiol and Cannabigerol exert antimicrobial activity without compromising skin microbiota. https://www.mdpi.com/1422-0067/24/3/2389 
• (2022)
• The Safety and Effectiveness of Commercially available Cannabidiol Products for Health and Well-being: A randomized, Multi-arm Open-label waitlist-controlled trial. (Saleska, et al, 2022) https://www.liebertpub.com/doi/full/10.1089/imr.2022.0081 
• Dr. Sulak and Healer.com's guide to CBD/CBDa: https://healercbd.com/wp-content/uploads/2021/05/Healer-CBD-CBDA-eBook.pdf?utm_source=Klaviyo&utm_medium=flow&_kx=fVI32Zji5D8YALVRl8Kk8eO_XaFEb7CrKqw0kSWrhcU%3D.Tb8HXH 
• The complete guide to CBD (cannabidiol): https://www.leafly.com/news/cbd/what-is-cbd?utm_source=SailThru&utm_medium=email_news&utm_campaign=Newsletters_11272019_Wed
• FDA Says CBD Products Run ‘Real Risks’. Rather than regulate, FDA issues misinformation:  https://cannabisnow.com/fda-says-cbd-products-run-real-risks/?utm_campaign=Daily%20Morning%20News&utm_source=hs_email&utm_medium=email&utm_content=80147502&_hsenc=p2ANqtz-81tCS3wQBF3QB_siRiNgXZYkyIfhHxPPjXFwKzZMdeME7vIQXoUcCte1cF6915mAKR-9AIYlew3bTa1rB7EMHKxWQixw&_hsmi=80147709 
• The FDA is worried about CBD. Should you be concerned?   https://www.leafly.com/news/cbd/the-fda-is-worried-about-cbd-should-you-be-concerned?utm_source=SailThru&utm_medium=email_news&utm_campaign=Newsletters_12042019_Wed&utm_term=%5BTWS%5D%20%26%20%5BMaster%20%2B%20Not%20Dormant%5D